目的 观察应用来氟米特(Leflunomide,LEF)联合激素治疗IgA肾病的疗效和安全性。方法 选择IgA肾病患者63例,分为LEF合并激素治疗组(LEF组)及大剂量激素治疗组(激素组),观察治疗前和治疗6个月、12个月后的24 h尿蛋白定量、血清白蛋白、肾小球率过滤(eGFR)、收缩压、舒张压等实验室指标的变化,并进行疗效评价。结果 LEF组和激素组治疗6个月和12个月后的24 h尿蛋白定量、收缩压、舒张压均较治疗前显著下降(P0.05)。结论 LEF联合激素可以作为治疗IgA肾病的选择之一 ...
彭鲲 +8 more
doaj
[Serum inter-alpha-trypsin inhibitor heavy chain H3 is identified as a potential biomarker for myopenia in patients with rheumatoid arthritis using proteomic profiling]. [PDF]
Wu T +10 more
europepmc +1 more source
[Multiple myeloma with massive proliferation of signet ring cell like plasma cells: a case report]. [PDF]
Bai ZY +6 more
europepmc +1 more source
[Resveratrol protects barrier function of mouse brain microvascular endothelial cell monolayers with oxygen/glucose deprivation and PM<sub>2.5</sub> exposure by maintaining mitochondrial dynamics balance]. [PDF]
Qin M +9 more
europepmc +1 more source
[Pathological characteristics of pigmented pretibial patches and vascular-immune abnormalities in diabetic patients]. [PDF]
Liu X, Chang B.
europepmc +1 more source
[Shihu Mixture alleviates diabetic cardiomyopathy in rats by Sirt3-mediated upregulation of myocardial mitochondrial mitophagy pathway]. [PDF]
Lin X, He Y, Shi H, Liu J, Hu H.
europepmc +1 more source
[Rheumatoid arthritis combined with IgG4-related disease successfully treated with rituximab: A case report]. [PDF]
Ding Y, Wang L, Li C, Lu Z, Shi L.
europepmc +1 more source
[POEMS syndrome misdiagnosed as systemic sclerosis: A case report]. [PDF]
Liang J, Zhang X, Yao H.
europepmc +1 more source
[Systemic lupus erythematosus complicated by autoimmune nodopathy: A case report]. [PDF]
Wei C, Yang Y, Zhao X, Liu X, Jia Y.
europepmc +1 more source
[Aerobic exercise regulates macrophage polarization and improves insulin resistance in mice: the mediating role of miR-221-3p]. [PDF]
Li N, Zhang L, Guo Q, Zhou Y, Liu C.
europepmc +1 more source

