Results 11 to 20 of about 58,058 (133)
Highlights Lipid profiles of small extracellular vesicles (sEVs) in patients with diabetes or diabetic cardiovascular disease are rarely reported. n‐3 docosahexaenoic acid (DHA)‐enriched triacylglycerol (TG) was found to decrease in sEVs from serum of patients with diabetic cardiovascular disease (DM‐CAD).
Wei Ding +3 more
wiley +1 more source
Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang +6 more
wiley +1 more source
Highlights Childhood obesity was significantly associated with the increased risk of insulin resistance (IR). There were 12 metabolites co‐associated with childhood obesity and IR, including seven amino acid and five fatty acid metabolites. The combination of body mass index standard deviation score and key metabolites could effectively predict the ...
Wu Yan +5 more
wiley +1 more source
Highlights In the first trimester, the plasma mitochondrial DNA (mtDNA) was higher in women who developed gestational diabetes mellitus (GDM) than in women who did not develop GDM during their pregnancy. The increased levels of plasma mtDNA were independent of age and fasting plasma glucose levels in the first trimester.
Dushyant Kumar Sahu, Jessy Abraham
wiley +1 more source
Background – Hymenoptera envenomation with honey bee (Apis mellifera) and paper wasp (Polistes spp.) may cause life‐threatening anaphylaxis in dogs. In human patients, clinical history, intradermal testing (IDT) and measurement of allergen‐specific serological immunoglobulin (Ig)E (sIgE) are used to support a diagnosis of Hymenoptera venom ...
Hilary H. Chan +3 more
wiley +1 more source
ABSTRACT Skin wound injuries are often accompanied by bacterial infections and severe inflammation. Especially, M1‐type macrophages at the wound site can trigger a cascade of inflammatory responses, mediating a vicious cycle of inflammation. Meanwhile, hypoxia further exacerbates vascular damage and constriction in the wound microenvironment, thereby ...
Xianfeng Wang +6 more
wiley +1 more source
ABSTRACT Periodontitis is a chronic infectious oral disease triggered by periodontopathogenic bacteria, resulting in the progressive inflammation and destruction of the tissues surrounding teeth. To achieve reprogramming of the infectious microenvironment for periodontitis therapy, a nanoformulation was proposed by loading polydopamine (PDA) with ...
Hao Liang +14 more
wiley +1 more source
Serum levels of soluble CD93 in patients with chronic renal failure [PDF]
慢性腎不全(CRF)患者における可溶性CD93(sCD93)の血清レベルを自主開発した抗ヒトCD93抗体(mNI-11)とオリジナル構築酵素抗体法(EIAキット)を用いて検討した。その結果、CRF患者血清中のsCD93は健康人と比較して有意に高値を示した。また、血清中インターロイキン-6(IL-6)もCRF患者は健康人に比較して有意に高値を示した。CRF患者血清中のsCD93と腎機能マーカーである尿素窒素、血清クレアチニン、血清シスタチンCとの相関を解析したところ、いずれも強い相関を示した ...
Heihachi MIGITA +14 more
core
ABSTRACT Objective Complete hydatidiform mole and coexisting normal fetus (CHMCF) is a rare condition for which there is significant heterogeneity in diagnosis, counseling and management of complications. The objective of this study was to summarize the prevalence of clinical outcomes in reported cases of CHMCF.
N. Salmeri +8 more
wiley +1 more source
通过对培养时间、培养温度、刀豆蛋白A(ConA)质量浓度和鳗鲡血清质量分数4个参数的测定,确定欧洲鳗鲡(Anguilla anguilla)外周血淋巴细胞转化试验四甲基偶氮唑(MTT)法的实验条件。结果表明,在培养时间为42-90 h,培养温度分别为15.0℃、20.0℃、25.0℃和30.0℃时,细胞培养液中ConA质量浓度分别为0、10μg/mL、20μg/mL和30μg/mL,鳗鲡血清质量分数分别为0、5%、10%和15%时,淋巴细胞于20.0℃、含10μg/mL ConA,
关瑞章, 冯建军, 郭松林
core

