Results 31 to 40 of about 62,817 (184)

探讨NGAL血尿同测对高血压肾病辅助诊断的临床价值

open access: yesZhongguo shiyan zhenduanxue, 2018
目的探讨中性粒细胞明胶酶相关脂质运载蛋白(NGAL)血尿同测对高血压肾病辅助诊断的临床价值。方法选择2015年2月至2017年5月确诊为高血压肾病的100例患者作为研究对象,其中尿微量白蛋白(MAlb)/尿肌酐(UCrea)比值(ACR)小于30mg/g设为正常清蛋白尿组,其余患者归入高清蛋白尿组,同时选择50例体检健康者作为对照组,同时测定血清及尿液NGAL、血清胱抑素C(Cys-C)、MAlb、血清和尿液肌酐浓度水平,对结果进行对比分析。结果对比对照组 ...
柴巨川
doaj  

Study on the interactions of typical PAHs and their metabolites with serum albumin and their controlling ways using cyclodextrins [PDF]

open access: yes, 2016
血清白蛋白是血浆中含量最丰富的运输蛋白,对血液中许多内、外源物质具有广普的结合能力,具有重要的生理功能。多环芳烃(PolycyclicAromaticHydrocarbons,PAHs)及其代谢物可与血清白蛋白形成稳定的加合物,由此随血液循环转运分布至各组织器官,引起毒性效应。该结合过程也可对血清白蛋白的结构和功能产生不利影响。因此,深入研究PAHs及其代谢物与血清白蛋白的结合作用,探究PAHs对血清白蛋白结构和功能的影响及寻求该结合作用的调控方式对了解PAHs在生物体内的赋存状态、毒性强度及致毒机制 ...
张静
core  

Applying Bergmann's Rule to Species Conservation Planning 贝格曼法则在物种保护规划中的应用

open access: yesIntegrative Conservation, Volume 4, Issue 2, Page 120-125, June 2025.
Although Bergman's rule has extensively been studied, its implications in species conservation have not been clear, especially in the context of climate change (global warming). Here, we discuss the potential applications of the “rule” based on IUCN's (2022) Red List and suggest species' body size to be an important ecological indicator in future long ...
Qinfeng Guo   +4 more
wiley   +1 more source

应用荧光PCR技术检测6500例患者血清HBV DNA的实验研究

open access: yesZhongguo shiyan zhenduanxue, 2002
目的 揭示血清乙肝病毒标志物 (HBVM)与血清HBVDNA含量相关性。方法 采用ELISA法对血清、HB VM进行检测 ;对HBVM阳性 6 5 0 0例患者血清采用荧光PCR法定量检测HBVDNA。结果 在HBVM阳性的 6 5 0 0例血清中 ,有 3982例占 6 1 3% ,HBVM标志物阳性者血清均有HBVDNA阳性。血清HBsAg、HBeAg、抗 HBc阳性者HBVDNA阳性率占 96 9% ,大于 10 6copies/ml者占 72 1% ,HBsAg、抗 HBe、抗 ...
高俊芬   +4 more
doaj  

The role and mechanism of IL-33 in gout [PDF]

open access: yes, 2016
摘要 研究目的:以MSU诱导的小鼠实验性急性痛风为痛风研究模型,来探讨IL-33在急性痛风中的作用及其机制。 研究方法和结果: 1.重组小鼠IL-33的原核表达以及纯化 GST-IL-33融合蛋白经过原核表达、纯化,去除GST标签等步骤,获得了较高纯度的的mrIL-33。 2.对急性痛风患者血清中IL-33的研究 通过收集临床急性痛风患者41例(男39例,女2例)年龄26~91岁,平均58.3岁和44例年龄、性别与之匹配的健康志愿者的血清标本,检测血清中IL-33的含量。结果显示急性痛风患者血清中IL ...
苏群
core  

Screening for pre‐eclampsia using pregnancy‐associated plasma protein‐A or placental growth factor measurements in blood samples collected at 8–14 weeks' gestation

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 5, Page 567-574, May 2025.
ABSTRACT Objectives To assess the value of pregnancy‐associated plasma protein‐A (PAPP‐A) in screening for preterm pre‐eclampsia (PE) (delivery < 37 weeks' gestation) measured in maternal blood samples collected before 11 weeks, and to compare the screening performance of PAPP‐A with that of placental growth factor (PlGF) from blood samples collected ...
L. Rode   +21 more
wiley   +1 more source

慢性HBV感染患者血清cccDNA与HBVDNA、HBeAg关系研究

open access: yesZhongguo shiyan zhenduanxue, 2009
目的研究慢性HBV感染患者血清cccDNA与HBVDNA、HBeAg关系。方法采用分子信标PCR技术检测156例慢性HBV感染患者血清cccDNA。结果血清HBVDNA、HBeAg阳性组的血清cccDNA阳性率分别与阴性组相比较差异有显著性 ...
覃亚勤   +7 more
doaj  

Examination of dialysis patients by a systematic review focused on serum phosphorus value [PDF]

open access: yes, 2008
In November 2006, The Japanese Society for Dialysis Therapy (JSDT) announced its first guideline, "The guideline for the management of secondary hyperparathyroidism in chronic dialysis patients," which gives the recommended range of management target ...
Tsukiji, Makoto
core   +1 more source

Ongoing outbreak of maternal parvovirus B19 infections in Germany since end of 2023: consequence of COVID‐19 pandemic?

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 456-461, April 2025.
Abstract Objective To investigate the ongoing parvovirus B19 (B19V) outbreak among pregnant women in Germany and its connection to the coronavirus disease 2019 (COVID‐19) pandemic. Methods This retrospective cohort study analyzed anonymous data regarding serologically confirmed B19V infections during pregnancy between January 2014 and April 2024 across
J. Jiménez Cruz   +14 more
wiley   +1 more source

乳腺癌患者血清可溶性Fas水平变化及其意义

open access: yesZhongguo shiyan zhenduanxue, 2007
目的检测乳腺癌患者血清可溶性Fas(sFas)水平,探讨手术对血清sFas的影响。方法采用酶联免疫吸附试验法(ELISA),检测76例乳腺癌患者及100例正常人血清sFas水平,并比较乳腺癌患者手术前后血清sFas水平。结果血清sFas浓度与临床分期、雌激素受体有关,各期乳腺癌患者血清sFas水平明显高于正常对照组;Ⅳ期乳腺癌患者血清sFas水平明显高于其它各期,Ⅲ期明显高于Ⅱ期,Ⅱ期明显高于Ⅰ期;乳腺癌患者术后血清sFas水平明显低于术前。结论血清sFas水平与乳腺癌的发生发展有关 ...
黄国民   +4 more
doaj  

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