Results 41 to 50 of about 135,387 (227)

探讨NGAL血尿同测对高血压肾病辅助诊断的临床价值

open access: yesZhongguo shiyan zhenduanxue, 2018
目的探讨中性粒细胞明胶酶相关脂质运载蛋白(NGAL)血尿同测对高血压肾病辅助诊断的临床价值。方法选择2015年2月至2017年5月确诊为高血压肾病的100例患者作为研究对象,其中尿微量白蛋白(MAlb)/尿肌酐(UCrea)比值(ACR)小于30mg/g设为正常清蛋白尿组,其余患者归入高清蛋白尿组,同时选择50例体检健康者作为对照组,同时测定血清及尿液NGAL、血清胱抑素C(Cys-C)、MAlb、血清和尿液肌酐浓度水平,对结果进行对比分析。结果对比对照组 ...
柴巨川
doaj  

Development of a Pt(II) compound based on indocyanine green@human serum albumin nanoparticles: integrating phototherapy, chemotherapy and immunotherapy to overcome tumor cisplatin resistance

open access: yesRare Metals, Volume 43, Issue 11, Page 6006-6022, November 2024.
Graphical abstract AbstractCisplatin resistance is the main cause for the failure of cancer therapy. To solve the problem, we proposed to develop a novel human serum albumin (HSA) nanoplatform to integrate chemotherapy, photothermal therapy (PTT) and immunotherapy.
Xue‐Yu Man   +7 more
wiley   +1 more source

应用荧光PCR技术检测6500例患者血清HBV DNA的实验研究

open access: yesZhongguo shiyan zhenduanxue, 2002
目的 揭示血清乙肝病毒标志物 (HBVM)与血清HBVDNA含量相关性。方法 采用ELISA法对血清、HB VM进行检测 ;对HBVM阳性 6 5 0 0例患者血清采用荧光PCR法定量检测HBVDNA。结果 在HBVM阳性的 6 5 0 0例血清中 ,有 3982例占 6 1 3% ,HBVM标志物阳性者血清均有HBVDNA阳性。血清HBsAg、HBeAg、抗 HBc阳性者HBVDNA阳性率占 96 9% ,大于 10 6copies/ml者占 72 1% ,HBsAg、抗 HBe、抗 ...
高俊芬   +4 more
doaj  

Performance of machine‐learning approach for prediction of pre‐eclampsia in a middle‐income country

open access: yesUltrasound in Obstetrics &Gynecology, Volume 63, Issue 3, Page 350-357, March 2024.
ABSTRACT Objective Pre‐eclampsia (PE) is a serious complication of pregnancy associated with maternal and fetal morbidity and mortality. As current prediction models have limitations and may not be applicable in resource‐limited settings, we aimed to develop a machine‐learning (ML) algorithm that offers a potential solution for developing accurate and ...
J. Torres‐Torres   +10 more
wiley   +1 more source

Mechanistically Investigation for The Significance of Secreted Proteins in Diagnosis of Breast Cancer [PDF]

open access: yes, 2016
分泌蛋白对于乳腺癌的发生、发展起着至关重要的作用。有研究表明,分泌蛋白协同作用可促进正常乳腺细胞在软琼脂上的生长,结果提示多个分泌蛋白水平的变化可能是乳腺癌发生、恶化的标志。本研究拟利用乳腺癌临床血液样本,分析血清中几种分泌蛋白的含量,探讨几种分泌蛋白联用在乳腺癌诊断中的意义,并进一步研究这些分泌蛋白在促进乳腺癌细胞迁移、侵袭过程中的作用。 本文首先用ELISA双抗体夹心方法检测临床血清样本中IL6、IL9、IL21、FGF1、FGF10、FGF14的含量,结果表明IL6,FGF1 ...
胡修永
core  

慢性HBV感染患者血清cccDNA与HBVDNA、HBeAg关系研究

open access: yesZhongguo shiyan zhenduanxue, 2009
目的研究慢性HBV感染患者血清cccDNA与HBVDNA、HBeAg关系。方法采用分子信标PCR技术检测156例慢性HBV感染患者血清cccDNA。结果血清HBVDNA、HBeAg阳性组的血清cccDNA阳性率分别与阴性组相比较差异有显著性 ...
覃亚勤   +7 more
doaj  

The diffusion of enoxacin into the prostatic fluid in the chronic prostatitis patient [PDF]

open access: yes, 1988
慢性前立腺炎患者の血清中および前立腺液中のエノキサシン(ENX)濃度を測定した.血清濃度は平均1.24 μg/ml, 前立腺液内濃度は平均0.69 μg/ml, 対血清比は平均0.58と高い値を示した.今回求められた前立腺液濃度は代表的グラム陰性桿菌である大腸菌や変形菌のENXの80%最小発育阻止濃度を上回る結果であるTo examine the diffusion of enoxacin into the prostatic fluid of patients with chronic ...
中野, 洋二郎   +4 more
core  

乳腺癌患者血清可溶性Fas水平变化及其意义

open access: yesZhongguo shiyan zhenduanxue, 2007
目的检测乳腺癌患者血清可溶性Fas(sFas)水平,探讨手术对血清sFas的影响。方法采用酶联免疫吸附试验法(ELISA),检测76例乳腺癌患者及100例正常人血清sFas水平,并比较乳腺癌患者手术前后血清sFas水平。结果血清sFas浓度与临床分期、雌激素受体有关,各期乳腺癌患者血清sFas水平明显高于正常对照组;Ⅳ期乳腺癌患者血清sFas水平明显高于其它各期,Ⅲ期明显高于Ⅱ期,Ⅱ期明显高于Ⅰ期;乳腺癌患者术后血清sFas水平明显低于术前。结论血清sFas水平与乳腺癌的发生发展有关 ...
黄国民   +4 more
doaj  

Determination of lithium in serum by emission spectrophotometry using "Spectraspan" [PDF]

open access: yes, 1980
Lithium in serum was determined by a plasma emissionspectrophotometer "Spectraspan" (low power d.c. plasma are, operating on argon). The opitimum condition for ashing of serum by low temperature was studied.
Mifune, Masaaki
core   +1 more source

瘦素在闭经、不孕症的作用研究

open access: yesZhongguo shiyan zhenduanxue, 2009
目的探讨瘦素对闭经、不孕的影响,肥胖与血清瘦素水平的关系。方法通过放射免疫分析方法检测45例月经正常者和28例闭经患者及13例不孕患者中血清瘦素浓度,身体质量指数(BMI)与血清瘦素水平的关系。结果①闭经组及不孕组血清瘦素水平明显高于对照组,差异具有显著性 ...
张爱臣, 冷维春, 任丽华
doaj  

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