Results 81 to 90 of about 609 (149)
Zhongshan Daxue xuebao. Yixue kexue ban神经免疫系统对中枢神经系统的发育、衰老和损伤至关重要，逐渐成为人们研究的热点。髓系细胞触发受体２（TREM2）是免疫球蛋白超家族的一种跨膜受体，在中枢神经系统中主要表达于小胶质细胞。越来越多的研究表明，靶向TREM2对改善阿尔兹海默症、血管性痴呆、帕金森病、术后认知功能障碍、肥胖等疾病相关的认知功能障碍有很大的潜力。然而，其在认知功能障碍中的具体作用尚缺乏系统性的总结。故本文综述了TREM2在认知功能障碍中相关机制的最新研究进展，以期为认知功能障碍的治疗提供新的靶点。
师利敏, 徐平
doaj
[Preoperative serum magnesium as a biomarker for predicting delirium following non-cardiac surgery in elderly patients: a retrospective cohort study]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoYuan M +10 more
europepmc +1 more source
[Cross-century process of mental health surveys in China]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanHuang J, Liu Z, Zhang T, Huang Y.
europepmc +1 more source
[A study on the correlation between oral health status and cognitive impairment in elderly population]. [PDF]
Hua Xi Kou Qiang Yi Xue Za ZhiXu L +5 more
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban随着人口老龄化加剧，我国痴呆人口比例急剧上升，给家庭和社会带来沉重的经济和照护负担。阿尔茨海默病（AD）是一种老年期发病的进行性认知障碍疾病谱，表现为记忆减退、注意力和执行力下降，在疾病晚期甚至发展为痴呆，最终导致生活自理能力丧失，进一步加重家庭和社会压力。AD患者可处于数十年以上并无明显临床认知下降表现的临床前阶段，但脑中已存在显著病理变化，包括β淀粉样蛋白（Aβ）聚集形成老年斑、tau蛋白过度磷酸化聚集形成神经元纤维缠结，血管淀粉样蛋白沉积、突触和神经元丢失，以及神经炎症 ...
朱文悦, 李夏春
doaj
[Correlations between serum BDNF, IL-18 and hs-CRP levels in patients with acute cerebral infarction and vascular cognitive impairment]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanLi J +5 more
europepmc +1 more source
[5-Year Readmission Status and Risk Factors for Senile Dementia Patients: A Study Based on Chengdu Municipal Medical Insurance Database]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue Ban, 2022 Wang YY +6 more
europepmc +1 more source
[Yigong San improves learning and memory functions of APP/PS1 transgenic mice by regulating brain fluid metabolism]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZeng J +5 more
europepmc +1 more source