Results 21 to 30 of about 20,264 (157)
Zhongshan Daxue xuebao. Yixue kexue ban, 2008 【目的】研究人血管内皮细胞在建立NOD/SCID小鼠白血病微血管中的作用。【方法】NOD/SCID小鼠分3组:A空白对照组,B注射EC组,C建立白血病模型后注射EC组。通过免疫组化对NOD/SCID小鼠骨髓的血管生成及全身肿瘤负荷情况进行评价。【结果】C组骨髓微血管密度明显大于A、B组,白血病新生的微血管分支多紊乱,管腔较不规则,血管形态幼稚。【结论】用人血管内皮细胞成功建立NOD/SCID小鼠白血病微血管生成模型,可用于抗白血病血管生成及相关实验的研究。
郭海霞, 梁立阳, 吴燕云, 陈纯
doaj
The Role of Matrine and Mitogen-Ativated Protein Kinase/Extracellular Signal-Regulated Kinase Signal Transduction in the Inhibition of the Proliferation and Migration of Human Umbilical Veins Endothelial Cells Induced by Lung Cancer cells [PDF]
, 2009 Background and objective Matrine, one of the major alkaloid components of the traditional Chinese medicine Sophora roots, has a wide range of pharmacological effects including anti-inflammatory activities, growth inhibition and induction of cell ...
Jinchang LU +5 more
core
Review of additively manufactured zinc alloys by laser powder bed fusion for biomedical applications
Rare Metals, Volume 44, Issue 11, Page 8262-8291, November 2025.Graphical abstract AbstractZinc (Zn) and its alloys have emerged as promising candidates for biomedical materials, owing to their controlled degradation kinetics, intrinsic biocompatibility, and the release Zn2+ ions which are known to promote bone regeneration and tissue healing.
Xuan Yang +5 more
wiley +1 more source
Effects of Recombinant Human Endostatin and Docetaxel on MMP and its Following Anti-neoplastic Effect under Different Administration Sequences [PDF]
, 2010 Background and objective The aim of this study is to observe the changes of MMP-2 and its regulators, and to investigate the mechanism of the two administration sequences of recombinant human endostatin (rh-endostatin) and docetaxel.
Jing YUAN, Kai LI
core
Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 749-760, June 2025.ABSTRACT Objective Placental dysfunction can result in small‐for‐gestational age (SGA) or fetal growth restriction (FGR). The aim of this prospective cohort study was to assess the association of the cerebroplacental ratio (CPR) and other more conventional fetoplacental Doppler indices, circulating placental growth factor (PlGF) levels and soluble fms ...
J. Hong +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2020 氧化三甲胺(TMAO)是在人体摄入富含胆碱、左旋肉碱、卵磷脂等高脂营养物质后经肠道微生物转化后生成三甲胺(TMA),而后在肝脏的作用下生成的一种小分子化合物[1]。有相关研究表明,心血管疾病及不良心血管事件的发生与TMAO的产生、代谢过程相关,因此TMAO或可作心血管疾病诊断及治疗的潜在靶点[2,3]。本文就TMAO的生物学特性及其与心血管疾病的联系进行综述。
吴箴言 +5 more
doaj
The study on the mechanism of topical propranolol gel in therapy of superficial infantile hemangiomas [PDF]
, 2015 目的：探讨外涂普萘洛尔凝胶对浅表型婴幼儿血管瘤（IHs）患儿血浆碱性成纤维生长因子（bFGF）、基质金属蛋白酶-9(MMP-9)、血管内皮生长因子（VEGF）、肾素和血管紧张素Ⅱ（ATⅡ）水平的影响。初步探讨普萘洛尔凝胶治疗婴幼儿血管瘤的可能机制，以寻找治疗婴幼儿血管瘤高选择性用药，减少不良反应的发生。 方法：选取2013年2月至2014年2月厦门大学附属东方医院普通外科接受普萘洛尔凝胶治疗的33例婴幼儿血管瘤患儿，采用Achauer分级标准评估疗效，酶联免疫吸附试验（ELISA）检测患儿治疗前 ...
唐玉娟
core
Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 5, Page 624-632, May 2025.ABSTRACT Objectives Placental insufficiency contributes to many obstetric pathologies, but there is no bedside clinical tool to evaluate placental perfusion. We have developed a method to acquire multiple three‐dimensional (3D) power Doppler (PD) ultrasound (US) volumes of placental vasculature, with infrared camera tracking of the precise spatial ...
A. Xue +5 more
wiley +1 more source
糖尿病合并微血管病变患者血小板聚集、血栓烷B2生成与cAMP含量关系的初步探讨
Zhongshan Daxue xuebao. Yixue kexue ban, 1988 本文对40例糖尿病患者的血小板聚集、血栓烷B2生成和cAMP含量进行测定并探讨其与微血管病变的关系。结果表明:糖尿病患者血小板聚集增强、血栓烷B2生成增加,血小板cAMP含量降低。上述改变在无合并微血管病变组已存在,参与微血管病变的发生和发展。血小板血栓烷B2生成增加可能与血小板膜磷脂酶活性有关。
陈松源
doaj
Zhongguo shiyan zhenduanxue, 2020 血小板是血液循环中体积较小的无核细胞,由骨髓中的巨核细胞产生,其在止血和血栓形成的过程中发挥了重要的作用[1]。当血管发生损伤时,血小板能够黏附于受损的血管内皮,并形成血栓,进而发挥止血的作用[2]。然而 ...
杨颖, 田文沁
doaj