ABSTRACT Objectives Our aim was to examine the prenatal profiles of pregnancies affected by an atypical chromosomal aberration, focusing on pathogenic copy‐number variants (pCNVs). We also wanted to quantify the performance of combined first‐trimester screening (cFTS) and a second‐trimester anomaly scan in detecting these aberrations. Finally, we aimed
K. Gadsbøll +6 more
wiley +1 more source
糖尿病合并微血管病变患者血小板聚集、血栓烷B2生成与cAMP含量关系的初步探讨
本文对40例糖尿病患者的血小板聚集、血栓烷B2生成和cAMP含量进行测定并探讨其与微血管病变的关系。结果表明:糖尿病患者血小板聚集增强、血栓烷B2生成增加,血小板cAMP含量降低。上述改变在无合并微血管病变组已存在,参与微血管病变的发生和发展。血小板血栓烷B2生成增加可能与血小板膜磷脂酶活性有关。
陈松源
doaj
血小板是血液循环中体积较小的无核细胞,由骨髓中的巨核细胞产生,其在止血和血栓形成的过程中发挥了重要的作用[1]。当血管发生损伤时,血小板能够黏附于受损的血管内皮,并形成血栓,进而发挥止血的作用[2]。然而 ...
杨颖, 田文沁
doaj
The Role of Matrine and Mitogen-Ativated Protein Kinase/Extracellular Signal-Regulated Kinase Signal Transduction in the Inhibition of the Proliferation and Migration of Human Umbilical Veins Endothelial Cells Induced by Lung Cancer cells [PDF]
Background and objective Matrine, one of the major alkaloid components of the traditional Chinese medicine Sophora roots, has a wide range of pharmacological effects including anti-inflammatory activities, growth inhibition and induction of cell ...
Jinchang LU +5 more
core
Abstract The study sought to explore barriers to menstrual education between maternal figures and young girls. Menstruation is a key part of the reproductive process and affects young adolescent girls. Menstrual blood is perceived as contaminating and impure, leading to the socialization of women and girls undergoing menstruation to feel soiled and ...
Viwe Sobudula, Dhee Naidoo
wiley +1 more source
The study on the mechanism of topical propranolol gel in therapy of superficial infantile hemangiomas [PDF]
目的:探讨外涂普萘洛尔凝胶对浅表型婴幼儿血管瘤(IHs)患儿血浆碱性成纤维生长因子(bFGF)、基质金属蛋白酶-9(MMP-9)、血管内皮生长因子(VEGF)、肾素和血管紧张素Ⅱ(ATⅡ)水平的影响。初步探讨普萘洛尔凝胶治疗婴幼儿血管瘤的可能机制,以寻找治疗婴幼儿血管瘤高选择性用药,减少不良反应的发生。 方法:选取2013年2月至2014年2月厦门大学附属东方医院普通外科接受普萘洛尔凝胶治疗的33例婴幼儿血管瘤患儿,采用Achauer分级标准评估疗效,酶联免疫吸附试验(ELISA)检测患儿治疗前 ...
唐玉娟
core
Ovarian ectopic pregnancy: clinical characteristics, ultrasound diagnosis and management
ABSTRACT Objective To compare the clinical, ultrasound and biochemical characteristics of ovarian ectopic pregnancy (OEP) with those of tubal ectopic pregnancy (TEP). Methods This was a retrospective case–control study of women with OEP and those with TEP seen at a single center between December 2010 and February 2021.
S. A. Solangon, J. Naftalin, D. Jurkovic
wiley +1 more source
响 Impact on the apoptosis, invasion, proliferation ET-1 interfere with the formation of lung cancer [PDF]
摘要 目的: 肺癌是最常见的恶性肿瘤之一,威胁着全世界人民生命和健康。同时它也是世界上发病率和死亡率增长最快的疾病之一。而且大多数肺癌患者到晚期才被诊断发现,在现阶段肺癌的治疗中,它仍然是无法治愈的。Endothelin(ET),由内皮细胞合成,是一种生物活性肽,是一种强烈的血管收缩剂,具有很强的收缩血管作用,随着对内皮素研究的不断深入,人们发现内皮素与肿瘤关系密切,对肿瘤细胞的生长、增殖、转移、凋亡及化学耐药等都方面都有影响。ET能够产生细胞生长因子可以促进肿瘤DNA合成,基因表达和肿瘤细胞增殖 ...
张振宇
core
Roles of Sema3C on Breast Cancer Angiogenesis and Metastasis [PDF]
神经系统的发育依赖于一系列导向系统的控制。近年来的研究结果表明,神经导向系统不仅调控神经系统的发育,在血管新生和肿瘤发展等方面也发挥着重要的调控作用。神经生长导向因子Class3semaphorins(Sema3s)是脊椎动物中semaphorin家族中唯一一个的分泌型亚族。在Sema3s家族中的大部分成员在肿瘤发展过程中起抑制作用,而Sema3C却可能是一个促进肿瘤发展的因子。目前对于Sema3C在肿瘤中的作用主要集中在对肿瘤迁移、侵袭的影响等方面,对于肿瘤血管新生的影响还未见报道 ...
叶丽颖
core
Prenatal diagnosis and postnatal outcome of Type‐III vasa previa: systematic review of literature
ABSTRACT Objective Type‐III vasa previa (VP) is a rare form of VP, not necessarily associated with other placental or vascular anomalies, in which aberrant vessels run from the placenta to the amniotic membranes, near the internal cervical os, before returning to the placenta. Early diagnosis of Type‐III VP is important but technically challenging. The
M. Pozzoni +7 more
wiley +1 more source

