Quantitative Computed Tomography Study of Bone Mineral Density for Adults Residents in Foshan [PDF]
Objective: To study the relation between adult vertebral bone mineral density (BMD) and gender and age in Foshan, to explore the average BMD of each age group and osteoporosis (OP) incidence distribution in the region.
Cuiling ZHU +4 more
core +1 more source
The effects of miR-30c-1-3p regulating group ⅡA secretory phospholipase A2（sPLA2-ⅡA）expression on the pathogenic mechanism of atherosclerosis [PDF]
, 2015 动脉粥样硬化（Atherosclerosis，AS）是急性冠脉综合症、脑卒中等众多心脑血管疾病共同的病理基础。sPLA2-ⅡA在动脉粥样硬化病变处含量明显增多、活性显著增强，同时伴随中性粒细胞的增多。sPLA2-ⅡA以酶的催化水解作用和作为致炎因子的促炎症反应双重生物学作用参与AS发生发展的各个阶段。 MicroRNA（miRNA）是近年发现广泛存在于真核细胞中的高度保守的、非编码单链小分子RNA，具有最广泛的基因调节功能，参与机体多种生理、病理过程的调控。 我们运用miRNA靶基因预测软件发现miR ...
夏小春
core
Correlation of FRAIL scale and fragile index with adverse outcomes in elderly patients on maintenance hemodialysis [PDF]
Objective To explore the FRAIL scale and fragile index （FI） and adverse outcomes of elderly maintenance hemodialysis （MHD） patients. Methods From June 2020 to December 2022, 116 elderly patients on MHD were selected and assigned into two groups of ...
Fang Jin, Li-qun Gao, Su-xia Wang
core +1 more source
Research progress on lactylation in atherosclerosis [PDF]
Atherosclerosis (AS) serves as the primary pathological basis for cardiovascular and cerebrovascular diseases. Lactylation, a novel post-translational modification (PTM) linked to lactate molecules, functions as a critical interface between cellular ...
LAN Yining, MO Qin, QIN Chao
core +1 more source
Causes of death in patients undergoing maintenance hemodialysis a 10-year retrospective analysis in a single center [PDF]
Objective To retrospectively analyze the characteristics of maintenance hemodialysis (MHD) patients who have died in the past decade, with the aim of understanding the mortality rate, causes of death, and other factors in MHD patients. Methods A total of
YAN Junfang, WANG Deguang, WANG Ruifeng, LI Huai, YUAN Liang
core +2 more sources
Zhongshan Daxue xuebao. Yixue kexue ban, 2019 【目的】探讨吴茱萸次碱对血管平滑肌细胞钙化的作用及机制。【方法】本研究采用大鼠血管平滑肌细胞钙化体外模型，用不同浓度的吴茱萸次碱处理细胞，qRT-PCR检测成骨样分化基因Runx2、BMP2和Osterix的表达和茜素红染色测细胞钙化程度。此外，观察吴茱萸次碱对血管平滑肌细胞Sirt1表达水平的影响以及Sirt1抑制剂对细胞钙化的影响。【结果】茜素红素染色及钙离子浓度定量实验均显示不同浓度的吴茱萸次碱可明显地改善高磷高钙诱导的大鼠血管平滑肌细胞的钙化程度（136±10、75±6、52±6、31±5 ...
邵静, 陈安, 张秀丽, 杨平珍
doaj
Zhongguo shiyan zhenduanxue, 2022 转移性钙化(metastatic calcification,MC)是由于全身性的钙、磷代谢障碍,引起机体血钙或血磷升高,导致钙盐在未受损伤的组织内沉积,随血液循环异位于肾小管、肺泡壁等软组织或血管壁。转移性肺钙化(metastatic pulmonary calcification,MPC)是钙在肺组织中沉积,继发于无肺软组织损伤史的钙代谢异常。最常见的原因为慢性肾功能衰竭,血液透析,器官移植术后,原发性或继发性甲状旁腺功能亢进症,破坏性骨损害等[1-5]。发病率低,国内外报道以个案病例为主 ...
doaj
Related factors and prognostic impact of cardiac valve calcification in maintenance hemodialysis patients [PDF]
ObjectiveTo explore risk factors for cardiac valve calcification (CVC) in maintenance hemodialysis (MHD) patients and evaluate its impact on cardiovascular events and mortality.
Chengjun WANG +7 more
core +1 more source
Effect of Oxidized Dihydromyricetin on the Gel Property of Surimi from Silver Carp (Hypophthalmichthys molitrix) [PDF]
This study aimed to investigate the effect of oxidized dihydromyricetin (oDMY) on the gel properties of silver carp (Hypophthalmichthys molitrix) surimi. The changes in gel strength, rheological properties, water-holding capacity, microstructure, protein
Hui HONG +5 more
core +1 more source
Construction of a machine learning-based prediction model for mitral annular calcification [PDF]
Objective To develop a risk prediction model for mitral annular calcification (MAC) using various machine learning algorithms to enable early identification and risk assessment of MAC. Methods A total of 500 patients who were hospitalized and underwent
BAI Song +5 more
core +2 more sources