Results 1 to 10 of about 23,117 (73)

Rationale and design for the Blood Pressure Control Target in Diabetes (BPROAD) study 糖尿病血压控制目标(BPROAD)研究的原理和设计

Journal of Diabetes, Volume 15, Issue 12, Page 1029-1040, December 2023., 2023
Highlights The Blood Pressure Control Target in Diabetes (BPROAD) study is a multicenter, randomized controlled trial conducted in mainland China to test the hypothesis of whether intensive blood pressure (BP) management (systolic BP <120 mm Hg) has additional benefits over standard BP management (systolic BP <140 mm Hg) over a follow‐up period of up ...
The BPROAD Study Group, Guang Ning, Jiang He, Weiqing Wang, Yufang Bi, Dalong Zhu, Jiguang Wang, Shengdi Chen, Yu Xu, BPROAD coordinating team at Ruijin Hospital, Lawrence J. Appel, William C. Cushman, Vivian A. Fonseca, Jeff D. Williamson, David M. Reboussin, Yaling Han, Hongbing Shen, Minghui Zhao, Hui Wang   +18 more
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Blood pressure targets for prevention of cognitive decline in patients with diabetes and hypertension: Design of the Blood Pressure Control Target in Diabetes (BPROAD) Cognitive Study 高血压目标对于预防糖尿病和高血压患者的认知下降:BPROAD认知研究的设计

Journal of Diabetes, Volume 15, Issue 12, Page 1041-1047, December 2023., 2023
Highlights The optimal blood pressure (BP) target in patients with type 2 diabetes mellitus (T2DM) for the management of cognitive decline remains unknown. The Blood Pressure Control Target in Diabetes (BPROAD) Cognitive Study was designed to determine whether intensive BP treatment (systolic BP <120 mm Hg) reduces risk of dementia and mild cognitive ...
The BPROAD Study Group, Guang Ning, Jiang He, Weiqing Wang, Yufang Bi, Dalong Zhu, Jiguang Wang, Shengdi Chen, Yu Xu, BPROAD coordinating team at Ruijin Hospital, Lawrence J. Appel, William C. Cushman, Vivian A. Fonseca, Jeff D. Williamson, David M. Reboussin, Yaling Han, Hongbing Shen, Minghui Zhao, Hui Wang   +18 more
wiley   +1 more source

Patient experiences of continuous glucose monitoring and sensor‐augmented insulin pump therapy for diabetes: A systematic review of qualitative studies 糖尿病患者接受连续血糖监测和传感器增强胰岛素泵治疗的体验:对定性研究的系统综述

Journal of Diabetes, Volume 15, Issue 12, Page 1048-1069, December 2023., 2023
Highlights We identified that CGM can increase motivation for self‐management and confidence in treatments. A supportive treating team may help to reduce the practical and psychological burden in patients with type 1 and type 2 diabetes. Abstract Aims Blood glucose control is central to the management of diabetes, and continuous glucose monitoring (CGM)
Patrizia Natale, Sharon Chen, Clara K. Chow, Ngai Wah Cheung, David Martinez‐Martin, Corinne Caillaud, Nicole Scholes‐Robertson, Ayano Kelly, Jonathan C. Craig, Giovanni Strippoli, Allison Jaure   +10 more
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Decreased in n‐3 DHA enriched triacylglycerol in small extracellular vesicles of diabetic patients with cardiac dysfunction 糖尿病合并心脏功能障碍患者细胞外小囊泡中n‐3 DHA 富集的三酰甘油减少

Journal of Diabetes, Volume 15, Issue 12, Page 1070-1080, December 2023., 2023
Highlights Lipid profiles of small extracellular vesicles (sEVs) in patients with diabetes or diabetic cardiovascular disease are rarely reported. n‐3 docosahexaenoic acid (DHA)‐enriched triacylglycerol (TG) was found to decrease in sEVs from serum of patients with diabetic cardiovascular disease (DM‐CAD).
Wei Ding, Xuejuan Zhang, Dandan Xiao, Wenguang Chang   +3 more
wiley   +1 more source

Fatty acid β‐oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice 脂肪酸β‐氧化和线粒体融合参与胰高血糖素受体拮抗剂对糖尿病小鼠心脏微血管内皮细胞的保护作用

Journal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023
Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang, Rui Wei, Xiaona Cui, Zongzhe Jiang, Jin Yang, Lingyun Zu, Tianpei Hong   +6 more
wiley   +1 more source

The link between obesity and insulin resistance among children: Effects of key metabolites 儿童肥胖与胰岛素抵抗之间的联系:关键代谢产物的影响

Journal of Diabetes, Volume 15, Issue 12, Page 1020-1028, December 2023., 2023
Highlights Childhood obesity was significantly associated with the increased risk of insulin resistance (IR). There were 12 metabolites co‐associated with childhood obesity and IR, including seven amino acid and five fatty acid metabolites. The combination of body mass index standard deviation score and key metabolites could effectively predict the ...
Wu Yan, Su Wu, Qianqi Liu, Qingqing Zheng, Wei Gu, Xiaonan Li   +5 more
wiley   +1 more source

Plasma mitochondrial DNA is elevated in maternal serum at first trimester and may serve as a biomarker for prediction of gestational diabetes mellitus 血浆线粒体DNA在妊娠早期孕妇血清中升高，可能成为预测妊娠期糖尿病的生物标志物

Journal of Diabetes, Volume 15, Issue 12, Page 1095-1102, December 2023., 2023
Highlights In the first trimester, the plasma mitochondrial DNA (mtDNA) was higher in women who developed gestational diabetes mellitus (GDM) than in women who did not develop GDM during their pregnancy. The increased levels of plasma mtDNA were independent of age and fasting plasma glucose levels in the first trimester.
Dushyant Kumar Sahu, Jessy Abraham
wiley   +1 more source

A network meta‐analysis of association between cardiometabolic risk factors and COVID‐19 outcome severity 心血管代谢危险因素与COVID‐19严重程度关联的网络荟萃分析

Journal of Diabetes, Volume 15, Issue 11, Page 968-977, November 2023., 2023
Highlights Among 301 studies, diabetes mellitus was the most studied cardiometabolic risk factor. In the network meta‐analysis, cerebrovascular disease had the highest impact (relative risk [RR] 1.69; 95% CI, 1.65–1.73) on COVID‐19 outcomes compared to other cardiometabolic risk factors.
Alina Binbin Li, Bo Yang, Yufei Li, Rachel Huynh, Samuel Shim, Kenneth Lo, Jie Li, Andrew Zullo, Wen‐Chih Wu, Simin Liu   +9 more
wiley   +1 more source

Effect of dipeptidyl peptidase‐4 inhibitor on the progression of coronary artery disease evaluated by computed tomography in patients receiving insulin therapy for type 2 diabetes mellitus DPP‐4抑制剂对接受胰岛素治疗的2型糖尿病患者冠状动脉疾病进展的影响

Journal of Diabetes, Volume 15, Issue 11, Page 944-954, November 2023., 2023
Highlights Preclinical data showed that dipeptidyl peptidase‐4 inhibitors (DPP‐4is) may prevent insulin‐induced atherosclerosis. In patients treated with insulin for type 2 diabetes who underwent ≥2 serial coronary computed tomography angiographies(CCTA), a new obstructive coronary artery disease (OCAD) was less developed on the follow‐up CCTA in those
Young Choi, Seung‐Hyun Ko, Kiyuk Chang, Ki Dong Yoo, Sang‐Hyun Ihm   +4 more
wiley   +1 more source

Exosomal miR‐let‐7c‐5p is involved in the cognitive function of type 2 diabetes mellitus patients by interleukin 10: A cross‐sectional study 外泌体miR‐let‐7c‐5p通过白细胞介素10参与2型糖尿病患者的认知功能:一项横断面研究

Journal of Diabetes, Volume 15, Issue 11, Page 978-986, November 2023., 2023
Highlights Both interleukin‐10 levels and exosomal miR‐let‐7c‐5p levels are correlated with cognitive function in patients with type 2 diabetes mellitus. There is a negative association between interleukin‐10 levels and exosomal miR‐let‐7c‐5p levels in the plasma of patients with type 2 diabetes mellitus. Abstract Background Interleukin (IL)‐10 plays a
Hui Zhang, Shufang Yang, Wenwen Zhu, Tong Niu, Jue Wang, Mingyue Yang, Enlin Liu, Jumei Wang, Sumei Li, Haoqiang Zhang   +9 more
wiley   +1 more source