Results 21 to 30 of about 165,163 (164)

The link between obesity and insulin resistance among children: Effects of key metabolites 儿童肥胖与胰岛素抵抗之间的联系:关键代谢产物的影响

open access: yesJournal of Diabetes, Volume 15, Issue 12, Page 1020-1028, December 2023., 2023
Highlights Childhood obesity was significantly associated with the increased risk of insulin resistance (IR). There were 12 metabolites co‐associated with childhood obesity and IR, including seven amino acid and five fatty acid metabolites. The combination of body mass index standard deviation score and key metabolites could effectively predict the ...
Wu Yan   +5 more
wiley   +1 more source

Associations of blood biomarkers with arterial stiffness in patients with diabetes mellitus: A population‐based study 糖尿病患者血液生物标志物与动脉硬化的关系: 一项基于人群的研究

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 853-865, October 2023., 2023
Highlights Few studies have investigated the association of large‐scale biomarkers and pulse wave velocity (PWV) among diabetic patients. This study investigates the relationships of serum laboratory tests with PWV and explored the associations between PWV and all‐cause mortality among diabetic patients.
Yong‐Qi Liang   +9 more
wiley   +1 more source

Association between serum LDL‐C concentrations and risk of diabetes: A prospective cohort study 血清低密度脂蛋白胆固醇浓度与糖尿病风险之间的关联: 一项前瞻性队列研究

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 881-889, October 2023., 2023
Highlights Serum low‐density lipoprotein cholesterol (LDL‐C) levels were positively and significantly associated with a high risk of incident diabetes. Even in participants with normal LDL‐C levels (<130 mg/dL), a 1‐SD increase in LDL‐C levels was significantly associated with a higher risk of diabetes development.
Jiaojiao Huang   +13 more
wiley   +1 more source

Sensitivity to thyroid hormone and risk of components of metabolic syndrome in a Chinese euthyroid population 中国甲状腺功能正常人群对甲状腺激素的敏感性和代谢综合征组分的风险

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 900-910, October 2023., 2023
Highlights Mild acquired impaired thyroid hormone sensitivity was widespread among the general populations. Reduced thyroid hormone sensitivity was related with metabolic syndrome and its components. Impaired thyroid hormone sensitivity might affect the distribution of adipose tissue and muscle.
Fang Lv   +6 more
wiley   +1 more source

Development and validation of a multivariable risk prediction model for identifying ketosis‐prone type 2 diabetes 酮症倾向2型糖尿病多变量风险预测模型的建立与验证

open access: yesJournal of Diabetes, Volume 15, Issue 9, Page 753-764, September 2023., 2023
Highlights Ketosis‐prone type 2 diabetes mellitus (T2DM) is a novel type of diabetes mellitus, distinguished from type 1 diabetes mellitus and T2DM. Its clinical characteristics are complex and there is a lack of auxiliary tools for differential diagnosis.
Jia Zheng   +7 more
wiley   +1 more source

Association of gamma‐glutamyl transferase concentrations with all‐cause and cause‐specific mortality in Chinese adults with type 2 diabetes 中国成人2型糖尿病患者γ ‐谷氨酰转移酶浓度与全因死亡率及病因特异性死亡率的关系

open access: yesJournal of Diabetes, Volume 15, Issue 8, Page 674-684, August 2023., 2023
Highlights In people with type 2 diabetes, the risk of all‐cause, cardiovascular disease, and cancer mortality increased with higher gamma‐glutamyl transferase (GGT) concentrations. Stronger effects of GGT levels and all‐cause mortality were observed in the group with body mass index <25 kg/m2 and those with dyslipidemia.
Haoyu Guan   +12 more
wiley   +1 more source

Transdermal drug delivery in horses: An in vitro comparison of skin structure and permeation of two model drugs at various anatomical sites

open access: yesVeterinary Dermatology, Volume 34, Issue 3, Page 235-245, June 2023., 2023
Background – Oral and parenteral drug delivery in horses can be difficult. Equine‐specific transdermal drug formulations offer improved ease of treatment; development of such formulations requires a deeper understanding of the structural and chemical tissue barrier of horse skin. Hypothesis/Objectives – To compare the structural composition and barrier
Samuel C. Bizley   +3 more
wiley   +1 more source

Association of obesity under different metabolic status with adverse outcomes in patients with chronic myeloid leukemia: A retrospective cohort study 慢性髓系白血病患者不同代谢状态下肥胖与不良结局的相关性:一项回顾性队列研究

open access: yesJournal of Diabetes, Volume 15, Issue 5, Page 436-447, May 2023., 2023
Highlights To our knowledge, our study is the first to date to investigate the association between metabolically defined obesity and adverse outcomes in patients with chronic myeloid leukemia (CML). Metabolic abnormalities were associated with adverse outcomes in patients with CML, irrespective of obesity status.
Yingchun Dong   +11 more
wiley   +1 more source

Development and validation of risk prediction models for large for gestational age infants using logistic regression and two machine learning algorithms 使用Logistic回归和两种机器学习算法开发和验证大于胎龄儿风险预测模型

open access: yesJournal of Diabetes, Volume 15, Issue 4, Page 338-348, April 2023., 2023
Highlights The logistic regression model consisted of seven commonly used clinical indicators (including lipid profile) and gestational diabetes mellitus subtypes, with an area under the curve (AUC) of 0.760 for the training set and 0.748 for the internal validation set.
Ning Wang   +11 more
wiley   +1 more source

Remnant cholesterol is independently associated with diabetes, even if the traditional lipid is at the appropriate level: A report from the REACTION study 即使传统脂质处于适当水平, 残留胆固醇与糖尿病独立相关:来自REACTION研究的报告

open access: yesJournal of Diabetes, Volume 15, Issue 3, Page 204-214, March 2023., 2023
Highlights The first multicenter, large‐sample study of the relationship between remnant cholesterol (RC) and diabetes. RC is independently associated with diabetes. RC represents residual diabetes risk beyond traditional lipids. Abstract Background The association between remnant cholesterol (RC) and diabetes remains unclear because of limited study ...
Binqi Li   +11 more
wiley   +1 more source

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