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Zhongshan Daxue xuebao. Yixue kexue ban, 2004
【目的】探讨血液透析患者低密度脂蛋白受体(LDLR)基因多态性及其对脂代谢的影响。【方法】生化方法检测112例血液透析血清脂质水平,多聚酶链反应-限制性片段长度法检测105例血液透析患者LDLR内含子4TaqⅠ位点与80例血液透析患者外显子13AvaⅡ位点基因多态性。【结果】血液透析患者脂代谢紊乱主要表现为血清甘油三酯、载脂蛋白B水平显著增高。血液透析组与对照组LDLR内含子4TaqⅠ位点与外显子13AvaII位点基因型及等位基因分布频率无显著差异(P>0.05 ...
王玉新
doaj +1 more source

珠海市名中青年警察血脂水平及分布特征 [PDF]

Zhongshan Daxue xuebao. Yixue kexue ban, 2007
【目的】对珠海市部分中青年警察血脂水平进行调查分类，为特殊职业人群血脂异常防治提供信息。【方法】2140例健康体检的中青年警察按年龄性别分组，测定血清甘油三醑、总胆固醇、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇水平。根据我国“血脂异常防治建议”标准进行分类，并对血脂异常进行临床分型。查阅相关文献，将警察血脂特点与同期发表的文献资料进行对比分析。【结果】2140名中青年警察中，总胆固醇、甘油三醑和低密度脂蛋白胆固醇平均水平均随年龄的增大而上升．3项指标男性高于同年龄段女性 ...
陈筱潮 +5 more
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Decreased in n‐3 DHA enriched triacylglycerol in small extracellular vesicles of diabetic patients with cardiac dysfunction 糖尿病合并心脏功能障碍患者细胞外小囊泡中n‐3 DHA 富集的三酰甘油减少

Journal of Diabetes, Volume 15, Issue 12, Page 1070-1080, December 2023., 2023
Highlights Lipid profiles of small extracellular vesicles (sEVs) in patients with diabetes or diabetic cardiovascular disease are rarely reported. n‐3 docosahexaenoic acid (DHA)‐enriched triacylglycerol (TG) was found to decrease in sEVs from serum of patients with diabetic cardiovascular disease (DM‐CAD).
Wei Ding +3 more
wiley +1 more source

Fatty acid β‐oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice 脂肪酸β‐氧化和线粒体融合参与胰高血糖素受体拮抗剂对糖尿病小鼠心脏微血管内皮细胞的保护作用

Journal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023
Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang +6 more
wiley +1 more source

The link between obesity and insulin resistance among children: Effects of key metabolites 儿童肥胖与胰岛素抵抗之间的联系:关键代谢产物的影响

Journal of Diabetes, Volume 15, Issue 12, Page 1020-1028, December 2023., 2023
Highlights Childhood obesity was significantly associated with the increased risk of insulin resistance (IR). There were 12 metabolites co‐associated with childhood obesity and IR, including seven amino acid and five fatty acid metabolites. The combination of body mass index standard deviation score and key metabolites could effectively predict the ...
Wu Yan +5 more
wiley +1 more source

Associations of blood biomarkers with arterial stiffness in patients with diabetes mellitus: A population‐based study 糖尿病患者血液生物标志物与动脉硬化的关系: 一项基于人群的研究

Journal of Diabetes, Volume 15, Issue 10, Page 853-865, October 2023., 2023
Highlights Few studies have investigated the association of large‐scale biomarkers and pulse wave velocity (PWV) among diabetic patients. This study investigates the relationships of serum laboratory tests with PWV and explored the associations between PWV and all‐cause mortality among diabetic patients.
Yong‐Qi Liang +9 more
wiley +1 more source

Association between serum LDL‐C concentrations and risk of diabetes: A prospective cohort study 血清低密度脂蛋白胆固醇浓度与糖尿病风险之间的关联: 一项前瞻性队列研究

Journal of Diabetes, Volume 15, Issue 10, Page 881-889, October 2023., 2023
Highlights Serum low‐density lipoprotein cholesterol (LDL‐C) levels were positively and significantly associated with a high risk of incident diabetes. Even in participants with normal LDL‐C levels (<130 mg/dL), a 1‐SD increase in LDL‐C levels was significantly associated with a higher risk of diabetes development.
Jiaojiao Huang +13 more
wiley +1 more source

Sensitivity to thyroid hormone and risk of components of metabolic syndrome in a Chinese euthyroid population 中国甲状腺功能正常人群对甲状腺激素的敏感性和代谢综合征组分的风险

Journal of Diabetes, Volume 15, Issue 10, Page 900-910, October 2023., 2023
Highlights Mild acquired impaired thyroid hormone sensitivity was widespread among the general populations. Reduced thyroid hormone sensitivity was related with metabolic syndrome and its components. Impaired thyroid hormone sensitivity might affect the distribution of adipose tissue and muscle.
Fang Lv +6 more
wiley +1 more source

Development and validation of a multivariable risk prediction model for identifying ketosis‐prone type 2 diabetes 酮症倾向2型糖尿病多变量风险预测模型的建立与验证

Journal of Diabetes, Volume 15, Issue 9, Page 753-764, September 2023., 2023
Highlights Ketosis‐prone type 2 diabetes mellitus (T2DM) is a novel type of diabetes mellitus, distinguished from type 1 diabetes mellitus and T2DM. Its clinical characteristics are complex and there is a lack of auxiliary tools for differential diagnosis.
Jia Zheng +7 more
wiley +1 more source

Association of gamma‐glutamyl transferase concentrations with all‐cause and cause‐specific mortality in Chinese adults with type 2 diabetes 中国成人2型糖尿病患者γ ‐谷氨酰转移酶浓度与全因死亡率及病因特异性死亡率的关系

Journal of Diabetes, Volume 15, Issue 8, Page 674-684, August 2023., 2023
Highlights In people with type 2 diabetes, the risk of all‐cause, cardiovascular disease, and cancer mortality increased with higher gamma‐glutamyl transferase (GGT) concentrations. Stronger effects of GGT levels and all‐cause mortality were observed in the group with body mass index <25 kg/m2 and those with dyslipidemia.
Haoyu Guan +12 more
wiley +1 more source

pathology
medicine general
冠心病

脂联素
胰岛素抵抗
妊娠期糖尿病

血脂异常
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