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[Effects of Multiple Lifestyle Factors on Cardiovascular Biological Aging and Their Relative Contributions]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanCai J +4 more
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Zhongguo shiyan zhenduanxue动脉粥样硬化（AS）是一种慢性炎症性血管疾病，常累及心脑血管系统，引发严重临床后果。衰老是AS发生发展的重要危险因素，其中衰老内皮细胞分泌的衰老相关分泌表型（SASP）在AS进程中发挥关键作用。SASP通过多重通路促进炎症反应与血栓形成，并调控免疫细胞表型与功能，从3个方面加剧AS的进展：增强炎症反应、促进脂质沉积以及破坏斑块稳定性。本文综述了SASP在AS中的作用及其机制研究的最新进展，以期为AS的防治提供新的思路。
邵瑾瑾, 宋志明
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[Aging-Associated Oral Microbiota Dysbiosis and Hypofunction: Their Role in Alzheimer's Disease Pathogenesis]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanLi Y, Chen Y, Chen S, Huang X.
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[Protective effect and mechanism of TSPAN9-mediated mitocytosis in interleukin-1β-induced rat chondrocyte senescence]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiChen Q, Da W, Luo N, Shen B.
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Type 2 inflammation accelerates CD4<sup>+</sup> T-cell senescence in asthma. [PDF]
J Zhejiang Univ Sci BLiu H, Li Z, Sun Y, Aili A, Chang C.
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Transtext(e)s Transcultures è,è - Journal of Global Cultural Studies
Cléo Radar, 2009 openaire +1 more source
[Identification and Underlying Mechanisms of Immune Cell- and Senescence-Related Biomarkers in Atrial Fibrillation]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanHuang W, Liu E, Fu H.
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[Effect and mechanism of astaxanthin on the aging of high glucose-treated human skin fibroblasts]. [PDF]
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za ZhiTang LJ +6 more
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Zhongguo shiyan zhenduanxue全球人口老龄化加剧，2050年65岁以上人口占比预计达16%，神经退行性、心血管、代谢性疾病及肿瘤等衰老相关疾病发病率攀升，给公共卫生带来压力。当前这类疾病的早期诊断存在如侵入性操作风险高、检查费用高、普及性差、单一生物标志物特异性敏感性有限等局限，难以满足精准诊疗需求。多维度生物标志物可客观表征疾病发生发展的风险趋势，为疾病早期筛查、精准诊断和个体化干预提供依据。本文聚焦三类典型衰老相关疾病，梳理其分子、细胞、影像学及生理学参数等层面的多维度生物标志物研究进展，以期为衰老相关疾病的早期筛查 ...
田宇彤, 徐长霖, 孟庆宇
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