Results 21 to 30 of about 4,631 (166)

Deciding about the use of a Personal Safety Alerting Device—The need for a legitimation process: A qualitative study 使用个人安全警报装置的决定——合法化程序的必要性:定性研究

open access: yesJournal of Advanced Nursing, Volume 77, Issue 1, Page 331-342, January 2021., 2021
Abstract Aims To explore reasons, thoughts, motives, and influencing factors regarding the use or non‐use of Personal Safety Alerting Devices (PSADs) in the daily lives of community‐dwelling older persons. Design A qualitative descriptive study design was used.
Friederike J. S. Thilo   +4 more
wiley   +1 more source

A Study of Tian (沺) and Fu (傅) Based on Yisa Yifu (一沺一傅) in Medical Scripts of the Beijing University Collection (In Chinese) [PDF]

open access: yes, 2013
北京大學於2009年入藏一批西漢竹簡,當中醫簡711枚,內容大致分為「醫方目錄」、「醫方甲」、「醫方乙」和「醫經」四類,相關資料可參見李家浩、楊澤生〈北京大學藏漢代醫簡簡介〉一文(《文物》2011年6期)。根據整理者公佈之圖版可知,北大簡第2870簡記有古醫方「秦氏方」,簡文云:「一沺一傅,它惡傷亦可。  .秦氏方。」「秦氏」之名亦見《史記.扁鵲列傳》:「扁鵲者……,姓秦氏,名越人。」因此,過去嘗有學者認為「秦氏」有可能是戰國時期之神醫扁鵲。「一沺一傅」,「沺」於經傳中鮮見,疑應「洒」之誤,具「洗」義。「
Tang, PL
core   +1 more source

USP4 inhibits p53 and NF-κB through deubiquitinating and stabilizing HDAC2 [PDF]

open access: yes, 2015
蛋白泛素化/去泛素化修饰的异常与多种肿瘤的发生存在密切相关。作为去泛素化酶家族中的重要一员,USP4在一些肺癌细胞及其它人类癌细胞中呈现出高表达,说明USP4可能作为癌蛋白(oncoprotein)参与到对肿瘤细胞发生发展的调控。而目前对USP4参与肿瘤细胞发生的分子机制尚不清楚。我们的前期研究发现,USP4可以与去乙酰基转移酶HDAC2结合。初步研究表明USP4可以去泛素化并稳定HDAC2。进一步的研究发现,USP4通过HDAC2抑制p53的转录活性及NF-κB信号通路。在本项申请中 ...
李增鹏
core   +1 more source

基于引文内容分析的引用情感识别研究 [PDF]

open access: yes, 2018
[目的/意义]针对自动识别论文引用情感问题,提出一种基于引文内容分析的识别方法并进行可视化展示,克服基于简单引用频次计量无法区分不同引用情感的问题。[方法/过程]首先,利用正则表达式抽取出论文全文中的引文内容信息; 然后,利用 TF-IDF 算法筛选出引用情感特征词,结合情感词典,利用情感分析技术对引文内容进行引用情感识别; 最后,利用可视化工具展示出引用情感整体分布情况。[结果/结论]该方法能够有效识别出抗衰老领域论文数据集中引用情感情况。实验结果显示,该领域正面引用占总引用次数的21 ...
刘自强, 廖君华, 白如江
core  

Transitioning From L1 Medium of Instruction to L2 English Medium Instruction: The Role of Translanguaging in Contributing to EFL Students’ Language Learning Motivation

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT Research on English‐Medium‐Instruction (EMI) highlights inadequate support for students transitioning from L1‐medium‐instruction to EMI. To date, little research has focused on how L2 students’ adaptation to an EMI environment influences their L2 learning motivation (LLM).
Kevin W. H. Tai
wiley   +1 more source

Genetic analysis and gene mapping of panicle branches stay-green trait in rice [PDF]

open access: yes, 2016
水稻是重要的粮食作物之一,全球一半以上的人口以大米为主食。随着世界人口的增长,人们正面临着越来越严重的粮食危机。如何增加水稻产量一直是作物育种以及植物学研究的重要目标。近年来水稻遗传育种工作者发现了一些成熟期叶片的叶绿素不降解或仅少量降解而使叶片仍保持绿色的持绿型水稻品种,研究发现其叶片持绿性状多数属多基因控制的数量遗传,少数属隐性主效基因控制的质量性状遗传,相关基因大多已被鉴定及克隆。迄今为止,尚未见穗枝梗持绿性状的研究报道。佳辐占系本课题组育成的优质高产早稻品种,已在生产上大面积推广应用 ...
王永杰
core  

Lipid Nanoparticles Delivering ClpP‐mRNA Suppress Pyroptosis and Senescence in Intervertebral Disc Degeneration via mTOR/BNIP3‐Activated Mitophagy

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang   +7 more
wiley   +1 more source

鱼腥藻PCC7120细胞液泡的初步研究 [PDF]

open access: yes, 1999
从保存3个月以上的老化培养物中直接检查到游离液泡。液泡为标准圆球状,完全透明,大小相差极为悬殊,多数大型液泡吞噬了数个衰老藻细胞。采用低渗酶解,渗透冲击,低渗酶解和渗透冲击相结合,从培养3个月以上,2个月,1个月,18d,10d及3d的藻丝细胞都分离到液泡。液泡略大于细胞,泡内无吞噬物。培养3d的藻丝有15%的细胞分离到液泡 ...
郭厚良,金传荫,浦秋文,宋文贞,周云珍,杨清平
core  

NIR‐Responsive Nano‐Integrated Magnesium Phosphate Cement Promotes Bone Regeneration via Osteoblast‐Exosome‐Osteoclast Crosstalk

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang   +8 more
wiley   +1 more source

Research on the function of ANAC084 in Arabidopsis thaliana in response to the environmental stress [PDF]

open access: yes, 2016
ANAC084是NAC转录因子家族的一员,其编码一个206个氨基酸的小蛋白。在拟南芥中过表达ANAC084植株出现地上部分变小,莲座叶面积变小、颜色加深,生长周期偏长的表型,但是根的发育并不受影响,进一步的研究表明过表达ANAC084会使拟南芥叶片细胞变小同时使叶片细胞数量大大减少,从而造成植株变小。但是ANAC084-RNAi和ANAC084-SRDX植株在表型上和野生型没有明显区别。通过对ANAC084Pro:gANAC084:GFP:GUS植株进行GFP扫描和GUS染色研究ANAC084的表达模式,
钟小年
core  

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