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Research status of evaluation and nutrition interventions on frailty in the elderly by Traditional Chinese Medicine and western medicine (老年衰弱中西医评估及营养干预的研究现状)

open access: yes中西医结合护理, 2022
Frailty is a common geriatric syndrome and drawing more and more attention as increase in aging population. This paper reviewed the recent studies on frailty in the elderly from perspectives of concepts of frailty in the elderly, evaluation tools of ...
WANG Boyu (汪柏宇)   +1 more
doaj   +1 more source

Determining the impact of age and sex on the psychophysical and neurophysiological response to thermal pain across the adult lifespan 确定年龄和性别对成年期热痛的心理、生理和神经生理学反应的影响

open access: yesJournal of Advanced Nursing, Volume 77, Issue 3, Page 1546-1555, March 2021., 2021
Abstract Aims Determine sex‐ and age‐associated psychophysical and neurophysiological differences in the processing of pain across the adult lifespan. Design Preliminary, exploratory, cross‐sectional study. Methods Using psychophysics (to measure intensity and unpleasantness) and functional magnetic resonance imaging blood oxygenation level dependent ...
Sebastian W. Atalla   +8 more
wiley   +1 more source

Deciding about the use of a Personal Safety Alerting Device—The need for a legitimation process: A qualitative study 使用个人安全警报装置的决定——合法化程序的必要性:定性研究

open access: yesJournal of Advanced Nursing, Volume 77, Issue 1, Page 331-342, January 2021., 2021
Abstract Aims To explore reasons, thoughts, motives, and influencing factors regarding the use or non‐use of Personal Safety Alerting Devices (PSADs) in the daily lives of community‐dwelling older persons. Design A qualitative descriptive study design was used.
Friederike J. S. Thilo   +4 more
wiley   +1 more source

Nrf2在卵巢早衰中的研究进展

open access: yesZhongguo shiyan zhenduanxue, 2022
卵巢早衰(POF)又称为原发性卵巢功能不全早衰(POI),指女性40岁前因卵巢内卵泡耗竭或医源性损伤导致的卵巢功能衰竭。卵母细胞老化分为两种主要类型,包括排卵后衰老[1]和年龄相关衰老[2]。随着年龄增长,雌性繁殖力降低,卵泡数量下降及卵母细胞质量恶化称为“年龄相关衰老”[3]。
董文秋子, 李实, 张松灵
doaj  

细胞衰老与衰老相关疾病研究进展

open access: yes亚洲临床医学杂志, 2020
衰老(Senescence)是细胞功能逐渐退化的一种状态,在这种状态下细胞几乎丧失复制能力,并且细胞周期抑制基因p16INK4a 的表达升高。细胞衰老贯穿生物个体的整个生命过程,在各种生理以及病理过程中发挥重要的作用。一方面,衰老的细胞能够促进胚胎发育,伤口愈合和宿主免疫反应以及抑制肿瘤发生发展等。另一方面,随着年龄增长而在体内积累的衰老细胞也会对机体带来有害的影响。这些不能增殖的细胞产生衰老相关分泌表型(Senescence-Associated Secretory Phenotype,SASP ...
潇雨 田, 娜 卢
semanticscholar   +1 more source

A Study of Tian (沺) and Fu (傅) Based on Yisa Yifu (一沺一傅) in Medical Scripts of the Beijing University Collection (In Chinese) [PDF]

open access: yes, 2013
北京大學於2009年入藏一批西漢竹簡,當中醫簡711枚,內容大致分為「醫方目錄」、「醫方甲」、「醫方乙」和「醫經」四類,相關資料可參見李家浩、楊澤生〈北京大學藏漢代醫簡簡介〉一文(《文物》2011年6期)。根據整理者公佈之圖版可知,北大簡第2870簡記有古醫方「秦氏方」,簡文云:「一沺一傅,它惡傷亦可。  .秦氏方。」「秦氏」之名亦見《史記.扁鵲列傳》:「扁鵲者……,姓秦氏,名越人。」因此,過去嘗有學者認為「秦氏」有可能是戰國時期之神醫扁鵲。「一沺一傅」,「沺」於經傳中鮮見,疑應「洒」之誤,具「洗」義。「
Tang, PL
core   +1 more source

男性生殖衰老特征的多角度认识

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2022
随着婚育年龄推迟,大龄夫妇生育需求逐渐增加,生殖衰老成为社会发展面临的重要公共卫生问题。研究表明40~55岁可能为男性生育力的“分水岭”。然而,相比女性生殖衰老,男性生殖衰老特征缺乏鲜明特征,对机体的复杂影响表现为多方面。本篇综述中,我们从男性生殖内分泌、生殖腺,以及生殖附属性腺的衰老性变化角度,阐述对男性生殖衰老特征的认识。
李湘平, 邓春华
doaj  

USP4 inhibits p53 and NF-κB through deubiquitinating and stabilizing HDAC2 [PDF]

open access: yes, 2015
蛋白泛素化/去泛素化修饰的异常与多种肿瘤的发生存在密切相关。作为去泛素化酶家族中的重要一员,USP4在一些肺癌细胞及其它人类癌细胞中呈现出高表达,说明USP4可能作为癌蛋白(oncoprotein)参与到对肿瘤细胞发生发展的调控。而目前对USP4参与肿瘤细胞发生的分子机制尚不清楚。我们的前期研究发现,USP4可以与去乙酰基转移酶HDAC2结合。初步研究表明USP4可以去泛素化并稳定HDAC2。进一步的研究发现,USP4通过HDAC2抑制p53的转录活性及NF-κB信号通路。在本项申请中 ...
李增鹏
core   +1 more source

时空阶梯理论对经络和衰老的解释

open access: yes亚洲临床医学杂志, 2020
时空阶梯理论揭示,气是螺线矢量场,有两种方法生成:一种是靠能量流产生 : 另一种是靠随时间变化的能量场产生。经络的运行是双向运动,即收缩态能量向体内运动,膨胀态能量向体外运动。穴位是气场螺旋运动与皮肤交叉的地方,是神气出入的地方,穴位与穴位之间的距离正好是气场螺距的距离。气场以斐波那契螺旋方式展开,展开的次序与张仲景的六经辨证基本吻合。叶天士论证的卫气营血与脑波的 Beta(β)、Alpha (α)、Theta(θ) 和 Delta(δ) 波分别对应,按照时空阶梯理论可以推论出新的时空阶梯 ...
炳功 常
semanticscholar   +1 more source

Investigation and analysis of the frail status of elderly inpatients in Beijing (北京市三级甲等综合医院老年住院患者衰弱状况调查与分析)

open access: yes中西医结合护理, 2022
Objective To explore the influencing factors and current situation about frailty of the elderly patients in Beijing, and to provide references for further health assessment about elderly patients, in order to provide reference about choosing the right ...
LU Wei (陆薇)   +4 more
doaj   +1 more source

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