Results 11 to 20 of about 9,299 (107)
Effect and mechanism of microRNAs on various diabetic wound local cells microRNA对各种糖尿病创面局部细胞的作用及机制
Journal of Diabetes, Volume 15, Issue 11, Page 955-967, November 2023., 2023 Highlights For the first time, we have examined the impact of microRNA on diabetic wounds at a cellular level. We have analyzed how a particular microRNA influences different types of cells, uncovering its function and mechanism. This study furthers the discovery of the clinical potential of diverse microRNAs by evaluating their distinct effects and ...
Hongjie Li, Shengyu Jing, Hongbo Xu
wiley +1 more source
Journal of Traumatic Stress, Volume 36, Issue 5, Page 835-848, October 2023., 2023 Abstract This study is an update of the meta‐analysis we published in 2019 on the effectiveness of body‐ and movement‐oriented interventions (BMOIs) for adults with posttraumatic stress disorder (PTSD) in decreasing PTSD symptoms and secondary outcomes of depressive symptoms, sleep disturbance, and interoceptive awareness.
Minke M. van de Kamp +6 more
wiley +1 more source
Veterinary Dermatology, Volume 34, Issue 1, Page 53-58, February 2023., 2023 Background – The treatment of canine chronic cutaneous lupus erythematosus (CCLE) variants generally requires immunosuppression, which often results in potentially severe adverse effects. Janus kinase inhibitors, like oclacitinib, might be a valuable treatment option due to their rapid inhibition of the action of interferons known to be relevant in the
Richard G. Harvey +3 more
wiley +1 more source
Veterinary Dermatology, Volume 32, Issue 5, Page 477-e131, October 2021., 2021 Background – Interleukin (IL)‐31 is an important mediator in canine atopic dermatitis (cAD) and also may be dysregulated in other allergic diseases. Hypothesis/Objectives – To demonstrate the efficacy and safety of lokivetmab (canine anti‐IL‐31 monoclonal antibody) for treatment of pruritus associated with allergic dermatitis in dogs.
Leen Van Brussel +4 more
wiley +1 more source
Developmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019 目的 本国际临床指南由欧洲残疾儿童学会（the European Academy of Childhood Disability，EACD）牵头制定，旨在解决发育性协调障碍（developmental coordination disorder，DCD）的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题，通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础，以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类，最终转化为指南建议。并由国际 ...
Jing Hua +6 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 1, Page 71-78, July 2024.ABSTRACT Objective To validate externally the QUiPP App v.2 algorithms in an independent cohort of high‐risk asymptomatic women attending a preterm birth (PTB) surveillance clinic in Ireland. Methods This was a retrospective, single‐center, observational study assessing discrimination and calibration of the QUiPP App v.2 at six predetermined clinical ...
L. Creswell +4 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2000 目的 研究淋巴瘤初诊时患者血清乳酸脱氢酶（Ｓ－ＬＤ）、血清β２－微球蛋白（Ｓ－β２Ｍ）和尿β２－微球蛋白（Ｕ－β２Ｍ） 判断淋巴瘤预后的价值。方法回顾分析１１０例经病理确诊的淋巴瘤患者，初诊时Ｓ－ＬＤ、Ｓ－β２Ｍ和Ｕ－β２Ｍ水平与临床特点 及治疗效果的关系。结果 淋巴瘤患者三个指标均明显高于对照组。非霍奇金淋巴瘤（ＮＨＬ）三个指标高于霍奇金淋巴瘤 （ＨＤ），骨髓侵犯率也增高，对治疗的反应性则降低。结论初诊时，Ｓ－ＬＤ、Ｓ－β２Ｍ和Ｕ－β２Ｍ水平是淋巴瘤有意义的预后指 标。联合Ｓ－ＬＤ和Ｓ ...
洪春霖, 宋红蕾, 熊树民
doaj
DWI对鼻咽癌颈部小淋巴结转移瘤的诊断价值及其对放疗靶区的优化
Zhongguo shiyan zhenduanxue, 2021 目的探讨磁共振扩散加权成像（DWI）对鼻咽癌（NPC）小淋巴结转移瘤的诊断价值和NPC小淋巴结转移瘤表观扩散系数（ADC）的诊断阈值,及其对放疗靶区的优化。方法选取2017年9月至2019年12月广西科技大学第二附属医院收治的72例NPC患者,按检查方法分为对照组和观察组。对照组常规扫描确定放疗靶区,观察组DWI确定放疗靶区。测量颈部小淋巴结转移瘤、大淋巴结转移瘤和良性淋巴结ADC值,绘制受试者工作特征（ROC）曲线,确定诊断NPC颈部小淋巴结转移瘤的ADC诊断阈值和效能。比较两组放疗靶区勾画面积 ...
林灿洁, 唐爽, 文小芝, 何明盛
doaj
Zhongguo shiyan zhenduanxue, 2012 宫颈上皮内瘤变（CIN）是与宫颈浸润癌密切相关的一组癌前病变,它反映了宫颈癌发生、发展中的连续过程[1]。由于宫颈癌存在一段较长的、可逆性的癌前病变时期,大约要10年时间,因此,早起诊断和治疗CIN是防治宫颈癌的关键环节。为了评价阴道镜检查在CIN诊断中的应用价值 ...
陈军, 贾妍, 邹颖刚, 王玉辉
doaj
Zhongguo shiyan zhenduanxue, 2000 目的 研究淋巴瘤初诊时患者血清乳酸脱氢酶（Ｓ－ＬＤ）、血清β２－微球蛋白（Ｓ－β２Ｍ）和尿β２－微球蛋白（Ｕ－β２Ｍ） 判断淋巴瘤预后的价值。方法回顾分析１１０例经病理确诊的淋巴瘤患者，初诊时Ｓ－ＬＤ、Ｓ－β２Ｍ和Ｕ－β２Ｍ水平与临床特点 及治疗效果的关系。结果 淋巴瘤患者三个指标均明显高于对照组。非霍奇金淋巴瘤（ＮＨＬ）三个指标高于霍奇金淋巴瘤 （ＨＤ），骨髓侵犯率也增高，对治疗的反应性则降低。结论初诊时，Ｓ－ＬＤ、Ｓ－β２Ｍ和Ｕ－β２Ｍ水平是淋巴瘤有意义的预后指 标。联合Ｓ－ＬＤ和Ｓ ...
洪春霖, 宋红蕾, 熊树民
doaj