Results 11 to 20 of about 5,900 (119)

Decreased in n‐3 DHA enriched triacylglycerol in small extracellular vesicles of diabetic patients with cardiac dysfunction 糖尿病合并心脏功能障碍患者细胞外小囊泡中n‐3 DHA 富集的三酰甘油减少

open access: yesJournal of Diabetes, Volume 15, Issue 12, Page 1070-1080, December 2023., 2023
Highlights Lipid profiles of small extracellular vesicles (sEVs) in patients with diabetes or diabetic cardiovascular disease are rarely reported. n‐3 docosahexaenoic acid (DHA)‐enriched triacylglycerol (TG) was found to decrease in sEVs from serum of patients with diabetic cardiovascular disease (DM‐CAD).
Wei Ding   +3 more
wiley   +1 more source

Protective effects of nattokinase against microvasculopathy and neuroinflammation in diabetic retinopathy 纳豆激酶对糖尿病视网膜病变微血管病变和神经炎症的保护作用

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 866-880, October 2023., 2023
Highlights Nattokinase rescued endothelial dysfunction and pericyte loss in the diabetic retina. Nattokinase attenuated diabetes‐induced retinal inflammation and neurodegeneration. High mobility group box 1 signaling was involved in nattokinase‐mediated retinal protection.
Zijing Huang   +11 more
wiley   +1 more source

Increased glutamate in type 2 diabetes in the Korean population is associated with increased plasminogen levels 韩国2型糖尿病患者谷氨酸升高与纤溶酶原水平升高有关

open access: yesJournal of Diabetes, Volume 15, Issue 9, Page 777-786, September 2023., 2023
Highlights Increased glutamate is associated with the development of diabetes. Glutamate increases plasminogen (PLG) levels through glutamate metabotropic receptor 5 activation with various insulin resistance‐related stresses. Glutamate inhibits the conversion of PLG to plasmin by increasing plasminogen activator inhibitor‐1.
Hyo Jung Lee   +7 more
wiley   +1 more source

A Review of micro RNAs changes in T2DM in animals and humans miRNAs在2型糖尿病人类和动物中的变化

open access: yesJournal of Diabetes, Volume 15, Issue 8, Page 649-664, August 2023., 2023
Highlights MicroRNAs (miRNAs) are overexpressed in inflammation, insulin resistance, and type 2 diabetes mellitus (T2DM). Many types of miRNAs are changed during the T2DM progression. miRNAs have a potential role as a biomarker in T2DM diagnosis. Abstract Type 2 diabetes mellitus (T2DM) and its associated complications have become a crucial public ...
Mohammad Reza Afsharmanesh   +3 more
wiley   +1 more source

Equine allergic skin diseases: Clinical consensus guidelines of the World Association for Veterinary Dermatology

open access: yesVeterinary Dermatology, Volume 34, Issue 3, Page 175-208, June 2023., 2023
Abstract Background Allergic skin diseases are common in horses worldwide. The most common causes are insect bites and environmental allergens. Objectives To review the current literature and provide consensus on pathogenesis, diagnosis, treatment and prevention. Materials and Methods The authors reviewed the literature up to November 2022.
R. Marsella   +6 more
wiley   +1 more source

Autophagy in the retinal neurovascular unit: New perspectives into diabetic retinopathy 视网膜神经血管单元自噬:糖尿病视网膜病变的新视角

open access: yesJournal of Diabetes, Volume 15, Issue 5, Page 382-396, May 2023., 2023
HighlightsAutophagy is closely related to retinal neurovascular units in diabetes retinopathy. Different cells participate in the occurrence and development of diseases through autophagy, and targeted autophagy may be a new direction of treatment in the future. Emphasized the close relationship between diabetic retinopathy (DR) and autophagy Summarized
Xiongyi Yang   +6 more
wiley   +1 more source

Electroacupuncture reduces blood glucose by regulating intestinal flora in type 2 diabetic mice 电针通过调节2型糖尿病小鼠肠道菌群降低血糖

open access: yesJournal of Diabetes, Volume 14, Issue 10, Page 695-710, October 2022., 2022
Highlights Electroacupuncture (EA) regulates the intestinal flora by promoting intestinal motility. EA regulated the intestinal flora to reduce the level of systemic inflammation. EA lowering the blood glucose by the IKKβ/NF‐κB‐JNK‐IRS‐1‐AKT signal pathway.
Jing An   +7 more
wiley   +1 more source

Alterations in epidermal function in type 2 diabetes: Implications for the management of this disease 2型糖尿病患者表皮功能的变化及其对治疗的意义

open access: yesJournal of Diabetes, Volume 14, Issue 9, Page 586-595, September 2022., 2022
Highlights Individuals with type 2 diabetes display epidermal dysfunction. Epidermal dysfunction can provoke cutaneous and extracutaneous inflammation. Because of the pathogenic role of inflammation in type 2 diabetes, improvements in epidermal functions could benefit type 2 diabetes.
Mao‐Qiang Man   +3 more
wiley   +1 more source

The effect of a mixed cannabidiol and cannabidiolic acid based oil on client‐owned dogs with atopic dermatitis

open access: yesVeterinary Dermatology, Volume 33, Issue 4, Page 329-e77, August 2022., 2022
Background– Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti‐inflammatory actions. Objectives – To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD). Conclusions and clinical relevance – Cannabidiol/CBDA as an adjunct therapy decreased pruritus, and not skin ...
Melissa Loewinger   +4 more
wiley   +1 more source

Targeting the PI3K/Akt signaling pathway in pancreatic β‐cells to enhance their survival and function: An emerging therapeutic strategy for type 1 diabetes 一种新兴的1型糖尿病治疗策略:靶向胰腺β细胞中的PI3K/Akt信号通路以增强其存活和功能

open access: yesJournal of Diabetes, Volume 14, Issue 4, Page 247-260, April 2022., 2022
Highlights Phosphoinositide 3‐kinase (PI3K)/Akt signaling is an emerging promising therapeutic target for diabetes. Modulation of the PI3K/Akt signaling pathway, via protein and peptide‐based biologics, parasite‐derived molecules, plant extracts, or through microRNA interactions, will regulate the processes that determine the function of β‐cells and ...
Inah Camaya   +2 more
wiley   +1 more source

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