Results 11 to 20 of about 6,216 (149)
Abstract Objective A trial comparing prenatal with postnatal open spina bifida (OSB) repair established that prenatal surgery was associated with better postnatal outcome. However, in the trial, fetal surgery was carried out through hysterotomy. Minimally invasive approaches are being developed to mitigate the risks of open maternal–fetal surgery.
D. A. Lapa +9 more
wiley +1 more source
New approach for estimating risk of miscarriage after chorionic villus sampling
ABSTRACT Objective To estimate the risk of miscarriage associated with chorionic villus sampling (CVS). Methods This was a retrospective cohort study of women attending for routine ultrasound examination at 11 + 0 to 13 + 6 weeks' gestation at one of eight fetal‐medicine units in Spain, Belgium and Bulgaria, between July 2007 and June 2018.
M. M. Gil +15 more
wiley +1 more source
目的 本国际临床指南由欧洲残疾儿童学会(the European Academy of Childhood Disability,EACD)牵头制定,旨在解决发育性协调障碍(developmental coordination disorder,DCD)的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题,通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础,以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类,最终转化为指南建议。并由国际 ...
Jing Hua +6 more
wiley +1 more source
A terminology (or coding system) is a formal set of controlled vocabulary in a specific domain. With a well‐defined terminology, each concept in the target domain is assigned with a unique code, which can be identified and processed across different medical systems in an unambiguous way.
Yinsheng Zhang +2 more
wiley +1 more source
Chinese expert consensus on clinical application of recombinant oncolytic adenovirus in the treatment of malignant tumors [PDF]
Treatment using oncolytic virus as a new tumor immunologic agent has made continuous breakthroughs in basic and clinical research of tumor in recent years, and it is expected to play an important role in cancer immunotherapy in the future.
Expert Committee on Immunotherapy of Chinese Society of Clinical Oncology , Professional Committee on Cancer Biotherapy of Shanghai Anticancer Association
core +1 more source
Research on High Molecular Polymer Ultrasound Contrast Agent for Drug Delivery [PDF]
癌症是威胁人类健康的重大疾病之一,恶性肿瘤的治疗在很大程度上仍以化疗为主。肿瘤化疗药物大多数为细胞毒性药物,具有较大的毒副作用。靶向给药系统能将药物定向输送到治疗部位,提高治疗部位的药物浓度,减少药物用量,降低不良反应,提高药物的安全性、有效性和患者的顺应性,是目前抗肿瘤治疗领域研究的重点。最新研究表明,超声空化过程中产生的“空化效应”、“声孔效应”能够实现药物的体内定位释放和提高治疗效果。微泡超声造影剂(UCA)作为一种新型的体内靶向给药载体系统受到广泛关注 ...
刘洋
core
Adivasi (Tea Tribe) worldviews of living close to wild Asian elephants in Assam, India
Abstract In Assam state, northeastern India, human–elephant conflict mitigation has included technocentric measures, such as installation of barriers, alternative livelihoods, and afforestation. Such measures treat conflict as a technical problem with linear cause–effect relations and are usually ineffective over the long term because they do not ...
Sayan Banerjee +2 more
wiley +1 more source
Preparation of 10-hydroxycamptothecin loaded PLA microbubbles and evaluation of bioeffect on hepatocellular carcinoma cells induced by ultrasound [PDF]
摘要 癌症是威胁人类健康的重大疾病之一,恶性肿瘤的治疗在很大程度上仍以化疗为主。近年来,载药微泡联合超声辐照治疗肿瘤也日益受到重视。 羟基喜树碱(HCPT)是一种广谱的抗肿瘤药物,临床上主要剂型为注射用冻干粉。聚乳酸(PLA)有良好的生物相容性和生物降解性,在生物医学领域有广泛的应用前景。为了增加靶向部位血药浓度,降低给药量,减小毒副作用,本课题探索载羟基喜树碱-聚乳酸微泡的制备及超声辐照下对肿瘤细胞生物效应的影响。 本文的主要研究包括: (1)以聚乳酸为成膜材料 ...
朱佩娟
core
国家自然科学基金2001-2016年基于纳米技术相关研究的资助项目分析 [PDF]
目的为我国从事纳米技术,特别是纳米医学相关研究人员提供参考。方法对国家自然科学基金委员会在2001~2016年资助纳米技术相关项目的基本情况进行了总结。结果与结论纳米技术是研究结构尺寸在1~100 nm内材料的性质和应用的一种技术,在材料与制备,微电子和计算机技术,医学与健康,航天和航空,生物技术等多个方面具有广泛的应用前景,是跨学科的重要科技前沿,但目前在国内获得临床许可或上市的纳米医学相关产品十分匮乏 ...
吴彩胜 +4 more
core +1 more source
Clinical study on the myocardial reperfusion after PCI using intravenous myocardial contrast echocardiography in coronary diseases [PDF]
目的探讨经外周静脉进行心肌超声造影对冠状动脉介入治疗(PCI)术后心肌血流再灌注定量分析的价值。方法对15例冠心病患者分别于PCI术前及PCI术后经外周静脉注射造影剂,在对比脉冲序列成像(CPS)条件下行心肌超声造影(MCE)检查,采用自动追踪增强定量分析(ACQ)软件进行分析,得出造影剂强度A值及斜率β值以及A×β值、造影剂到达时间AT值及达峰时间TTP值。结果经外周静脉注入造影剂后能够获得清晰心肌显影,所有患者均获得较满意的左心室及心肌显影。异常灌注区域(N=60)的造影剂AT ...
刘丹丹
core

