A terminology (or coding system) is a formal set of controlled vocabulary in a specific domain. With a well‐defined terminology, each concept in the target domain is assigned with a unique code, which can be identified and processed across different medical systems in an unambiguous way.
Yinsheng Zhang +2 more
wiley +1 more source
Comparison of Three Risk Prediction Models for Carotid Atherosclerosis in Steelworkers [PDF]
BackgroundAs a leading cause of ischemic cerebrovascular disease, carotid atherosclerosis (CAS) lowers the productivity of steelworkers. An increasing number of scholars have used machine learning to identify readily available factors to predict the risk
WANG Jiaojiao, CHEN Yuanyu, ZHENG Ziwei, YANG Yongzhong, CHEN Zhe, LI Chao, WANG Haidong, WU Jianhui, WANG Guoli
core +1 more source
Predictive Value of Combined Use of Ultrasonographic Indicators for Central Lymph Node Metastasis in Papillary Thyroid Carcinoma [PDF]
BackgroundThe treatment scheme for papillary thyroid carcinoma (PTC) patients is related to whether lymph node metastasis is prevalent or not. The routine ultrasound indicator used alone has proven to have a low sensitivity to predict the presence of ...
ZHANG Xiaomei, KANG Yanfei, SANG Tian, CHENG Jing, LI Qiaoli, CAO Yuwen, MA Jinmei, SHI Linan, LI Wenxiao, LI Jun
core +1 more source
The diagnostic value of elastography and ultrasound contrast in papillary thyroid microcarcinoma [PDF]
目的 评估弹性成像与超声造影(CEUS)两种检查技术对鉴别诊断甲状腺微小乳头状癌(TMC)的价值。方法 对常规超声检测出且定性困难的73例80个甲状腺微小结节进行弹性成像及CEUS检查,所有结节均经手术病理证实。比较两种检查方法的准确性。结果 80个结节中CEUS诊断正确率为85.0%(68/80),其中6例TMC误诊为良性病变,6例良性结节误诊为TMC;弹性成像5分法诊断正确率为92.5%(74/80),其中3例TMC误诊为良性结节,3例良性结节误诊为TMC。性成像诊断甲状腺微小癌的敏感性94.0%,
An, Yuan +7 more
core +2 more sources
Chinese expert consensus on clinical application of recombinant oncolytic adenovirus in the treatment of malignant tumors [PDF]
Treatment using oncolytic virus as a new tumor immunologic agent has made continuous breakthroughs in basic and clinical research of tumor in recent years, and it is expected to play an important role in cancer immunotherapy in the future.
Expert Committee on Immunotherapy of Chinese Society of Clinical Oncology , Professional Committee on Cancer Biotherapy of Shanghai Anticancer Association
core +1 more source
Development of Radiolabeled tumor-specific targeting peptides for PET Imaging [PDF]
多肽具有优良的药动学特性和生物学活性,因此在PET分子影像领域,多肽类分子影像探针展现出广阔的应用前景和优势。本课题利用AlF螯合法标记多肽,开发出一系列PET探针,并对相应探针进行体外及体内生物学评价。本课题具体研究内容可分为四部分。 第一部分,肝癌是最常见也是最致命的癌症之一,对于肝癌转移复发目前尚无行之有效的诊断、治疗方法。本研究通过固相法合成NOTA-G-TMTP1,并利用18F标记制得PET探针[18F]AlF-NOTA-G-TMTP1。[18F]AlF-NOTA-G-TMTP1标记产率为 ...
李业森
core
国家自然科学基金2001-2016年基于纳米技术相关研究的资助项目分析 [PDF]
目的为我国从事纳米技术,特别是纳米医学相关研究人员提供参考。方法对国家自然科学基金委员会在2001~2016年资助纳米技术相关项目的基本情况进行了总结。结果与结论纳米技术是研究结构尺寸在1~100 nm内材料的性质和应用的一种技术,在材料与制备,微电子和计算机技术,医学与健康,航天和航空,生物技术等多个方面具有广泛的应用前景,是跨学科的重要科技前沿,但目前在国内获得临床许可或上市的纳米医学相关产品十分匮乏 ...
吴彩胜 +4 more
core +1 more source
Preparation of 10-hydroxycamptothecin loaded PLA microbubbles and evaluation of bioeffect on hepatocellular carcinoma cells induced by ultrasound [PDF]
摘要 癌症是威胁人类健康的重大疾病之一,恶性肿瘤的治疗在很大程度上仍以化疗为主。近年来,载药微泡联合超声辐照治疗肿瘤也日益受到重视。 羟基喜树碱(HCPT)是一种广谱的抗肿瘤药物,临床上主要剂型为注射用冻干粉。聚乳酸(PLA)有良好的生物相容性和生物降解性,在生物医学领域有广泛的应用前景。为了增加靶向部位血药浓度,降低给药量,减小毒副作用,本课题探索载羟基喜树碱-聚乳酸微泡的制备及超声辐照下对肿瘤细胞生物效应的影响。 本文的主要研究包括: (1)以聚乳酸为成膜材料 ...
朱佩娟
core
Preparation of paclitaxel loaded PLA-lecithin nanobubbles and study of ultrasound-mediated antitumor effect on bearing tumor mice [PDF]
超声造影剂(ultrasoundcontrastagent,UCA)除了应用于增强声学造影外,目前已经广泛地应用于基因治疗、药物输送、溶栓治栓及肿瘤治疗等领域,并向纳米级和功能化方向发展。由于超声破坏载药微泡可使微泡在特定组织释放药物,超声介导治疗开创了靶向药物传递的新途径。具有超声造影和载药双功能的常规微泡平均粒径为2~5µm,不能透过血管,且载药率较低;纳米级载药微泡由于其尺寸小而具有极强的穿透力,可穿过血管内皮细胞间隙实现血管外的靶向诊断与治疗,具有巨大的发展潜力。 对此 ...
刘欣欣
core
Contrast-enhanced ultrasound for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease [PDF]
BackgroundHepatocellular carcinoma occurs mostly in people with chronic liver disease. Worldwide, it ranks sixth in terms of incidence of cancer, and fourth in terms of cancer-related deaths.
Casazza, Giovanni +7 more
core +1 more source

