Results 41 to 50 of about 45,331 (170)
Conservation Biology, Volume 40, Issue 2, April 2026.Abstract Wildlife reintroductions are socioecological processes entailing the intentional movement of organisms by people. In animal reintroductions, there is growing recognition of the importance of human dimensions and efforts to integrate these into reintroduction projects. To conceptually reframe reintroductions as processes of renewed coexistence (
Roger Edward Auster +3 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2019 卵巢癌转移所致的化疗抵抗是患者死亡的主要原因,主要通过两种途径:腹腔种植转移和循环肿瘤细胞(CTCs)介导的血行转移。最新研究发现,卵巢癌更易通过血行转移途径发生大网膜转移[1],血小板及其受体在这一过程中发挥至关重要的作用。肿瘤细胞利用血小板促进自身存活和转移的分子机制包括黏附受体分子如P选择素、整合素 ...
陈俊宇 +6 more
doaj
Politics &Policy, Volume 54, Issue 2, April 2026.ABSTRACT The Great Depression was a turning point in the development of social programming in North America. This paper explores the politics of social policy expansion during the Great Depression in the United States and Canada through an analytical lens that combines the insights of historical institutionalism and the analysis of transnational ...
Daniel Béland +2 more
wiley +1 more source
Integrative Conservation, Volume 5, Issue 1, Page 59-73, March 2026.This research reveals the functional stability of mixed species foraging flocks (MSF) and their foraging height change with different taxonomic differences along the elevational gradient at Knuckles Montane Reserve, Sri Lanka. This offers new insights into how MSFs sustain with the elevational gradients supporting the altitudinal shifting species ...
Vimukthi. R. Gunasekeara +3 more
wiley +1 more source
Detection of EGFR and COX-2 Expression by Immunohistochemical Method on a Tissue Microarray Section in Lung Cancer and Biological Significance [PDF]
, 2010 Background and objective Epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2), which can regulate growth, invasion and metastasis of tumor through relevant signaling pathway, have been detected in a variety of solid tumors.
Congzhong ZHU, Juan LIU, Xinyun WANG
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Rare Metals, Volume 45, Issue 3, March 2026.ABSTRACT Cost‐effective and efficient non‐noble‐metal catalysts for selective lignin hydrogenolysis remain elusive, representing a significant challenge in biorefinery. Here, we prepared a nitrogen‐doped carbon supported CoNi bimetallic catalyst, which was successfully derived from zeolitic imidazolate framework (ZIF) via high‐temperature pyrolysis ...
Xingwei Luo +3 more
wiley +1 more source
The effects of axon guidance factor Slit3 on metastasis of human fibrosarcoma [PDF]
, 2015 我们通过在纤维肉瘤细胞HT1080过表达Slit3基因，分析Slit3对肿瘤细胞侵袭转移作用.Transwell侵袭实验中，Slit3过表达后抑制HT1080的迁移侵袭，在裸鼠皮下成瘤实验中，肿瘤体积明显变小、重量明显降低，Slit3过表达后抑制HT1080肿瘤细胞的侵袭转移。此外肿瘤切片HE染色后发现GFP组有病灶点，而slit3过表达则少见，这个结果说明，Slit3显著抑制HT1080细胞转移。slit3过表达后MMP2,MMP9的表达明显降低，而MMP3，MMP13表达量上调 ...
刘咏梅
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Zhongguo shiyan zhenduanxue, 2007 目的研究人脑转移瘤及瘤周围脑组织水通道蛋白的表达和调控特征,认识水通道蛋白的异常表达在脑水肿形成和消除中的作用。方法对5例肺腺癌脑转移病例经手术切除的肿瘤组织提取总RNA并进一步行RT-PCR反转录扩增明确脑转移瘤组织中水通道蛋白的表达类型,再对肿瘤组织病理切片行相应水通道蛋白的免疫组化染色,测量切片的灰度值。结果水通道蛋白4（AQP4）在脑转移瘤周围脑组织高表达,而在转移瘤组织内部未见表达。在瘤组织周围,距离瘤组织较远的区域AQP4染色较浅,紧贴瘤组织的区域AQP4染色显著加深 ...
刘军, 赵彬, 宿跃田, 刘丽丹
doaj
Expression and Clinical Relevance of uPA and ET-1 in Non-small Cell Lung Cancer [PDF]
, 2011 Background and objective uPA and ET-1 proteins have been reported to be up-regulated in some of human cancers. The aim of this study is to investigate the alteration and clinical relevance of uPA and ET-1 protein levels in non-small cell lung cancer ...
Boshi WANG +7 more
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N-Myc-Interacting Protein (NMI)蛋白抑制胃癌上皮间质转化（EMT）的研究 [PDF]
, 2016 上皮间质转化（EMT）与多种生长因子和转录因子相关，可以通过多种信号转导通路起作用，并在胚胎发育、损伤修复、许多慢性疾病及肿瘤的发生和发展中起着重要的作用，然而EMT在胃癌发生过程中的分子机制并不清楚。 核因子-κB（NF-κB)可以与多种基因启动子部位的κB位点发生特异性的结合并促进其转录表达，进而调控肿瘤的发生，影响EMT的进程。我们的工作发现了一个新的通过调控抑制NF-κB通路调控胃癌中EMT的蛋白-NMI(N-MycandSTATinteractor)。研究结果显示 ...
侯静静
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