Results 41 to 50 of about 45,563 (170)
Zhongguo shiyan zhenduanxue, 2019 卵巢癌转移所致的化疗抵抗是患者死亡的主要原因,主要通过两种途径:腹腔种植转移和循环肿瘤细胞(CTCs)介导的血行转移。最新研究发现,卵巢癌更易通过血行转移途径发生大网膜转移[1],血小板及其受体在这一过程中发挥至关重要的作用。肿瘤细胞利用血小板促进自身存活和转移的分子机制包括黏附受体分子如P选择素、整合素 ...
陈俊宇 +6 more
doaj
Rare Metals, Volume 45, Issue 4, April 2026.ABSTRACT Piezocatalysis has garnered unprecedented research enthusiasm for applications in energy and environmental fields, as it can harvest the tiny vibration energy from the natural environment and convert it into electrical energy to drive catalytic reactions.
Feixue Gao +9 more
wiley +1 more source
A Clinical Observation of Concomitant Therapy of Erlotinib and Whole Brain Radiotherapy in Patients of NSCLC Combined with Brain Metastases [PDF]
, 2009 Background and objective Treatments to brain metastases in patients of NSCLC include operation, chemotherapy and radiotherapy, while the disease control rate of brain lesions is not so good, the media survival time is 4-6 months.
Jing ZHAO, Lihong ZHANG, Qiang FU
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The Role of Political Ideology in Shaping South Korea's Foreign Policy and Its Implications
Asian Politics &Policy, Volume 18, Issue 2, April 2026.ABSTRACT South Korea's foreign policy toward its neighbors frequently shifts when there is a leadership change from one ideological group to another. For instance, when power shifts from progressives to conservatives, South Korea's relations with the United States and Japan tend to improve while its ties with China and North Korea deteriorates.
Alec Chung
wiley +1 more source
Detection of EGFR and COX-2 Expression by Immunohistochemical Method on a Tissue Microarray Section in Lung Cancer and Biological Significance [PDF]
, 2010 Background and objective Epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2), which can regulate growth, invasion and metastasis of tumor through relevant signaling pathway, have been detected in a variety of solid tumors.
Congzhong ZHU, Juan LIU, Xinyun WANG
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Zhongguo shiyan zhenduanxue, 2007 目的研究人脑转移瘤及瘤周围脑组织水通道蛋白的表达和调控特征,认识水通道蛋白的异常表达在脑水肿形成和消除中的作用。方法对5例肺腺癌脑转移病例经手术切除的肿瘤组织提取总RNA并进一步行RT-PCR反转录扩增明确脑转移瘤组织中水通道蛋白的表达类型,再对肿瘤组织病理切片行相应水通道蛋白的免疫组化染色,测量切片的灰度值。结果水通道蛋白4（AQP4）在脑转移瘤周围脑组织高表达,而在转移瘤组织内部未见表达。在瘤组织周围,距离瘤组织较远的区域AQP4染色较浅,紧贴瘤组织的区域AQP4染色显著加深 ...
刘军, 赵彬, 宿跃田, 刘丽丹
doaj
从胶济铁路的修建看近代对华技术转移中的冲突与适应 [PDF]
, 2013 1897年德国以武力占领胶州湾,1899年德国辛迪加成立山东铁路公司,负责胶济铁路的修筑和运营。筑路初期,德国人野蛮粗暴的行为方式导致与当地民众的多次暴力冲突。1900年袁世凯与山东铁路公司签订的《胶济铁路章程》有利于规范铁路公司的行为。义和团运动期间,筑路冲突达到顶峰。分析可知,引起筑路冲突的原因主要可归为文化因素(风水和坟墓文化)和利益因素(土地产权和农田排水)。山东铁路公司通过与山东官府和士绅合作,解决上述问题,并在一些重要城镇修建了通往火车站的公路 ...
王斌
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Correlations between IGF-IR Expression and Clinicopathological Factors and Prognosis in Patients with Lung Adenocarcinoma [PDF]
, 2010 Background and objective The incidence of lung adenocarcinoma increases rapidly, and IGF-IR is the key mediator of several growth factors signal transduction, therefore it plays an important role in the proliferation and differentiation of cancer cell ...
Baohui HAN +4 more
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EFNA4 Effecting On EphA2 Regulates Cell Adhesion And Metastasis In Breast Cancer [PDF]
, 2016 实验背景：肿瘤细胞对临近组织和器官的侵袭与远端转移，一直是肿瘤研究的热点。酪氨酸受体蛋白及其配体家族Ephs和Ephrins之间的作用被证实能够调控多种肿瘤细胞的形态，细胞骨架，进而影响细胞的迁移与转移。前期通过荧光定量RT-PCR，我们发现相对于正常组织来源的细胞系，EFNA4在乳腺癌和肝癌细胞系中表达较低。同时在建立的高低侵袭ZR-75-30乳腺癌细胞系中，EFNA4具有表达差异，而EFNA4在肿瘤中的作用鲜有报道。 实验方法与结果：在体外实验中 ...
王恒
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Expression and Clinical Relevance of uPA and ET-1 in Non-small Cell Lung Cancer [PDF]
, 2011 Background and objective uPA and ET-1 proteins have been reported to be up-regulated in some of human cancers. The aim of this study is to investigate the alteration and clinical relevance of uPA and ET-1 protein levels in non-small cell lung cancer ...
Boshi WANG +7 more
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