目的探讨胃癌及其癌前病变中端粒酶的表达。方法对纤维内窥镜下活检的胃组织采用对TRAP方法加以改进的银染TRAP法,检测了端粒酶活性。结果29例胃癌中阳性率(23/29)82.7%:胃溃疡8例及胃息肉1例皆未检测到端粒酶活性,慢性萎缩性胃炎伴肠上度化生(AGIM)8例中4例有端粒酶表达。胃癌及AGIM端粒酶阳性率与良性病变阳性率比较差异显著(P<0.05)。结论银染TRAP法具有检测标本用量少,周期短,灵敏度高,特异性强等优点。对胃活检组织进行端粒酶检测在胃癌诊断中具有重要意义 ...
王贵民, 吴迪, 谭毓铨
doaj
目的探讨胃癌及其癌前病变中端粒酶的表达。方法对纤维内窥镜下活检的胃组织采用对TRAP方法加以改进的银染TRAP法,检测了端粒酶活性。结果29例胃癌中阳性率(23/29)82.7%:胃溃疡8例及胃息肉1例皆未检测到端粒酶活性,慢性萎缩性胃炎伴肠上度化生(AGIM)8例中4例有端粒酶表达。胃癌及AGIM端粒酶阳性率与良性病变阳性率比较差异显著(P<0.05)。结论银染TRAP法具有检测标本用量少,周期短,灵敏度高,特异性强等优点。对胃活检组织进行端粒酶检测在胃癌诊断中具有重要意义 ...
王贵民 +6 more
doaj
[Effect of dephosphorylation of tumor metastasis suppressor gene <i>LASS2</i> on vacuolar ATPase activity and invasiveness of prostate cancer]. [PDF]
Liu Y +8 more
europepmc +1 more source
[Open experiment: QuEChERS combined with fluorescence derivatization for the detection of atrazine and its effect on enzyme activity]. [PDF]
Huang XH +5 more
europepmc +1 more source
Improvement of neutral protease activity of Bacillus amyloliquefaciens LX-6 by combined ribosome engineering and medium optimization and its application in soybean meal fermentation. [PDF]
Zhu Y +5 more
europepmc +1 more source
[Effects of PM2.5 and O3 sub-chronic combined exposure on ATP amount and ATPase activities in rat nasal mucosa]. [PDF]
Yan T +8 more
europepmc +1 more source
[Advances in research on the mechanisms of reactive oxygen species in platelet activation and thrombosis]. [PDF]
Shen RY, Xu KL, Qiao JL, Fu P.
europepmc +1 more source
[Research progress on protein lactylation modification in malignant tumors]. [PDF]
Dong H, Chen H, Zhang C.
europepmc +1 more source
目的为探究全球变暖背景下,放牧遗留效应对冻结期盐渍化草地土壤酶活性的影响。方法以河西走廊盐渍化草地为研究对象,设置对照(CK)、放牧(FCK)、增温(W)和增温+放牧(FW)4种处理方式,探究不同处理下土壤酶活性变化规律及空间分布特征。结果与CK相比,FCK处理显著提高土壤水分体积分数和全氮质量分数,降低土壤有机碳质量分数;W处理降低土壤水分体积分数,提高土壤有机碳和全氮的97.61%和16.89%;而FW处理均显著提高土壤水分体积分数、有机碳和全氮质量分数,全磷质量分数显著低于对照40.81 ...
孙佳星 +4 more
doaj
[Progress in regulating stem cell functions for repair and regeneration of craniomaxillofacial tissues]. [PDF]
Zhang H, Yang F, Yang R.
europepmc +1 more source

