Results 121 to 130 of about 37,717 (232)
The Role of PERK-eIF2α-Yap Signaling in the Development of Hepatocellular Carcinoma [PDF]
, 2016 已有研究证实，Hippo信号通路失活会造成肝脏肿大和肿瘤发生，其中Yap的活性在Mst1/2双敲除小鼠肝细胞癌的发生中非常重要；内质网稳态的异常调节也在多种癌症中出现，但未折叠蛋白反应(UPR)在组织稳态中的调节作用还不清楚。我们之前的研究工作发现，在Mst1/2双敲除的小鼠肝脏中UPR被明显激活；进一步研究发现，UPR中的PERK支路能够调控Yap的转录。因此，我们想探究Hippo信号通路和UPR信号通路在肝癌发生发展中的关系。 我们认为Mst1/2双敲除小鼠肝脏中存在的慢性内质网应激 ...
江铭婷
core
International Journal of Applied Linguistics, EarlyView.ABSTRACT This study examines multilingual practices in research interviews, focusing on English lexical insertions in Chinese‐language research interviews with teachers of Chinese in Australian secondary schools, and treating these code‐switches as analytically meaningful rather than incidental.
Chengwen Yuan, Tianwei Zhang, Gary Bonar
wiley +1 more source
Gaoya dianqi, 1976 近年来,国内外对并联间隙放电特性,借助概率论作了分析,得出了一些计算公式。但要具体使用这些公式,还必须先有单个间隙的一些放电试验数据;而且这些公式也需要用试验来检验其正确性。本文介绍了该单位在对单个间隙最得试验数据后,应用这些公式作了并联间隙放电特性的具体计算,并将计算结果与并联间隙直接试验结果作了比较。
杨济三
doaj
Research on the Livelihood and Changes of GuangHui Village in North Hunan Province [PDF]
, 2016 光辉村是湘北地区典型的多姓氏杂居村落，该村所拥有的河湖平原地貌与亚热带季风气候使得村民形成了与之相适应的以水稻种植为主的生计方式。作为一个传统上以水稻种植业为主的村落，种粮是村民们最主要的生计手段。除种植水稻外，村人还种植蔬菜、养殖禽畜与鱼类作为粮食生产以外的补充，以此能够自给自足。自上世纪80年代以来，光辉村的生计模式经历了从“水稻种植为主体、蔬菜种植、渔业、禽畜养殖为补充的传统自给自足的农业生计模式”转变为“农业为主体、外出务工为补充的生计模式”，之后再转变为以“农业为基础、外出务工为主体的生计模式”
刘波
core
International Journal of Applied Linguistics, EarlyView.ABSTRACT Collaborative writing has attracted increasing attention in English as a Foreign Language (EFL) instruction due to its potential to enhance learners’ writing competence. However, few studies have examined the comparative effects of collaborative versus independent writing on EFL learners’ individual performance, especially in higher‐order ...
Ting Huang, Chenze Wu, Wenkang Zhang
wiley +1 more source
Association between Polymorphisms of ERCC1 and Response in Patients with Advanced Non-small Cell Lung Cancer Receiving Cisplatin-based Chemotherapy [PDF]
, 2010 Background and objective Results of studies on genetic polymorphisms of ERCC1 gene in DNA repair pathway which may affect response to platinum-based chemotherapy and survival in patients with non-small cell lung cancer are conflicting.
Hui ZHANG +6 more
core
International Journal of Applied Linguistics, EarlyView.ABSTRACT Many existing rubrics for L2 argumentative writing prioritize form‐based linguistic accuracy and complexity while insufficiently addressing substantive argumentative rigor and effectiveness. This limitation is further complicated by cross‐cultural variation in rhetorical conventions and educational practices, which challenge the direct ...
Zihan Xu, Peiyun Liu
wiley +1 more source
500kV同塔双回线路过电压计算及杆塔操作冲击最小空气间隙选择
Dianci bileiqi, 2016 为了确定同塔双回输电线路操作过电压最小空气间隙,运用ATP计算了500kV太安-黄坪同塔双回空载线路合闸过电压、单相重合闸过电压、故障解环操作过电压,通过比较获得了相地2%最高过电压为1.82p.u,出现在线路末端距太安22%处。开展了500kV双回线路真型塔中相I串对下侧横担、下相I串对塔腿间隙操作冲击试验,获得了间隙距离与操作波放电特性曲线,结合最高过电压水平计算了中相I串对下侧横担、下相I串对塔腿最小安全间隙为2.75m和2.78m,为500kV同塔双回线路操作过电压间隙选择提供了依据。
方书博, 李牧, 张晓琴, 张弓
doaj
Study on Oxidativestress and Bioaccumulation of Three Typical Brominated Flame Retardants in Oryzias melastigma Embryos [PDF]
, 2013 多溴联苯醚(Polybrominateddiphenylethers,PBDE)、四溴双酚A(TetrabromobisphenolA,TBBPA)和六溴环十二烷(Hexabromocyclododecane,HBCD)是目前世界上广泛使用的三大溴代阻燃剂(brominatedflameretardants,BFRs)。由于它们的亲脂性、环境稳定性、在生物体中的富集放大作用以及对水生生态系统和人体健康产生一定的毒性效应而受到各界的广泛关注和重视。本研究选取BDE-47 ...
赵琰琰
core