Results 61 to 70 of about 1,186 (135)
[Network pharmacology-based study of the therapeutic mechanism of resveratrol for Alzheimer's disease]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2021 Fang Y, Su Z, Si W, Liu Y, Li J, Zeng P.
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[Research on the application of convolution neural network in the diagnosis of Alzheimer's disease]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2021 Xu B, Ding C, Xu G.
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[Constructing Brain Aβ-Targeting Nanoparticles Loaded with EGCG for Treating Alzheimer's Disease in Mice]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue Ban, 2021 Yang P +4 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2019 【目的】对一个早发性家族性阿尔茨海默病家系（EOFAD）进行全外显子组测序，寻找可能引起致病的突变位点，为遗传咨询和产前诊断提供参考。【方法】对该家系成员进行全外显子基因检测，随后运用Poly?Phen-2和SIFT等生物信息学软件进行突变基因有害性预测。【结果】测序结果显示家系中患者在TTC3基因的第9个外显子发生c.758A>G突变，导致所编码的TTC3蛋白的第253位氨基酸由原来的酪氨酸变为半胱氨酸（p.Tyr253Cys）。根据家系共分离及相关生物信息学分析得出该突变基因为可能致病的变异。【结论】
李燕坤 +6 more
doaj
Alzheimer病皮肤血管β-淀粉样蛋白免疫组化标记及应用价值 附视频
Zhongguo shiyan zhenduanxue, 2000 目的 标记阿尔茨海默病皮肤血管β－淀粉样蛋白，寻找其特异性的实验室诊断指标。方法 选用链霉素化过氧 化酶标记物，使用合成的β－淀粉样蛋白免源性抗血清和天然的β－淀粉样蛋白单抗，采用ＳＡＢＣ法分别对年龄相匹配的８ 例老年性痴呆，８例多梗塞性痴呆和１２例非痴呆患者皮肤血管中的淀粉蛋白进行免疫组化标记。结果三组样本中淀粉蛋白 沉积的阳性率ＡＤ ６２．５％，ＭＩＤ３７．５％，ＮＤＣ８．３％。ＡＤ组较ＮＤＣ及ＡＤ组合并ＭＩＤ组较ＮＤＣ组有显著性意义（Ｐ＜０．０５）。 结论 标记皮肤β ...
郝洪军, 袁锦楣, 曹桂华
doaj
[Analysis of brain perfusion single-photon emission tomography images using an easy Zscore imaging system for early diagnosis of Alzheimer's disease]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2021 Wang S +7 more
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