目的通过整合生物信息学分析与临床验证,筛选冠状动脉粥样硬化性心脏病(CHD)细胞焦亡关键基因,并评估其作为生物标志物的诊断价值。方法基于GEO数据库GSE113079数据集筛选差异表达基因,结合LASSO回归与随机森林算法确定关键基因。纳入2023年5月至2024年8月在广东省人民医院就诊的CHD患者630例及健康体检对照246例,采用实时定量PCR检测外周血样本目标基因表达水平,分析其与临床分型、血管病变支数及Gensini评分的相关性。结果筛选出5个关键基因(PRKACA、CHMP6、GZMB ...
杨玉静 +7 more
doaj
[Machine learning-based prediction model for caries in the first molars of 9-year-old children in Suzhou]. [PDF]
Chen L, Wang X, Zhu K, Ren K, Wu Z.
europepmc +1 more source
[Enhancement of radiomics-based machine learning models for predicting efficacy of high-intensity focused ultrasound ablation of uterine fibroids using undersampling methods]. [PDF]
Cui Y +5 more
europepmc +1 more source
目的植被恢复通过改变土壤特性和根系特征,显著影响土壤分离能力(SDC),为明确红壤丘陵区植被恢复对SDC的影响机制。方法以南方红壤区常见的4种植被恢复措施为研究对象,通过SDC冲刷试验,系统评估各措施对SDC的影响,并探讨土壤性质和根系特征对SDC的调控作用。结果1)植被恢复措施均提高土壤有机质、全氮和全钾等养分含量,降低土壤体积质量、崩解系数和SDC。2)SDC与土壤含水量、有机质、全氮、全磷、速效磷、速效钾、pH及根重密度呈现显著相关,其中SDC与pH呈显著正相关(p<0.05)。3 ...
吴洁玲 +6 more
doaj
[Artificial intelligence in predicting pathological complete response to neoadjuvant chemotherapy for breast cancer: current advances and challenges]. [PDF]
He S, Li X, Xie Y, Hou J, Han B, Nie S.
europepmc +1 more source
[Research advances on the application of artificial intelligence technology in the diagnosis and treatment of sepsis patients]. [PDF]
Zhang YW +7 more
europepmc +1 more source
[Research progress and future prospects for artificial intelligence in the diagnosis and treatment of fatty liver disease]. [PDF]
Lin YY, Liu F, Rao HY.
europepmc +1 more source
[Detection of neurofibroma combining radiomics and ensemble learning]. [PDF]
Liu Y +6 more
europepmc +1 more source
[Early Alzheimer's disease recognition via multimodal hand movement quality assessment]. [PDF]
Yang G +5 more
europepmc +1 more source
[Recent advances in artificial intelligence for auxiliary diagnosis and management of neonatal necrotizing enterocolitis]. [PDF]
Jiang Q, Zhang L.
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