Results 1 to 10 of about 760 (89)
2013—2023年喀什地区黑热病流行病学及临床特征 [PDF]
目的探讨喀什地区黑热病患者的流行病学和临床特征,以提高诊疗水平。方法对2013年1月至2023年12月喀什地区第一人民医院收治的71例黑热病患者的临床资料进行回顾性分析。结果71例黑热病患者中,0岁~5岁患者最多,占52.11%(37/71),男女比例为 0.92: 1,患者发病多在冬春季。临床特征主要表现为发热、乏力、食欲下降以及脾脏、肝脏增大。实验室检查主要为三系减少,血清白球比倒置、转氨酶升高、C反应蛋白及降钙素原升高。抗rK39抗体检测的阳性率为100%(23/23),骨髓镜检的阳性率为91 ...
李娇玲 +6 more
doaj +3 more sources
Blastic plasmacytoid dendritic cell neoplasm complicated with acute myeloid leukemia: a case report [PDF]
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) complicated with acute myeloid leukemia (AML) is a rare disease. In this article, we reported the diagnosis and treatment of one patient of BPDCN complicated with AML who presented with fever as the ...
Kong Lihua, Qin Lili, Feng Anhua, Liu Zhenzhen, Tang Na, Zang Jikang, Wang Haiying
core +1 more source
Clinical Study of Venetoclax with Chemotherapy for Relapsed/Refractory Acute Myeloid Leukemia [PDF]
BackgroundAdults with relapsed/refractory acute myeloid leukemia (AML) have poor prognosis, very low long-term survival rate and cure rate, and limited chemotherapy regimens.ObjectiveTo investigate the safety and efficacy of venetoclax (VEN) with HAAG ...
CHEN Xiaofeng, WANG Meng, LI Zhongyu, LI Jiajia
core +1 more source
MedBench: A Large-Scale Chinese Benchmark for Evaluating Medical Large Language Models
The emergence of various medical large language models (LLMs) in the medical domain has highlighted the need for unified evaluation standards, as manual evaluation of LLMs proves to be time-consuming and labor-intensive.
Cai, Yan +6 more
core
A case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia [PDF]
Chronic myelomonocytic leukemia (CMML) complicated with immune thrombocytopenia (ITP) is rare. This article reports the clinical data of a patient with CMML complicated with ITP treated with a combination of venetoclax, ripertamab (an anti-CD20 ...
HAO Siguo, HUANG Fang, LIU Jiayu
core +1 more source
Systemic lupus erythematosus complicated with pure red cell aplasia: a case report and literature review [PDF]
This article reports a single case of a patient with systemic lupus erythematosus (SLE) combined with pure red cell aplasia (PRCA), and reviews 51 additional cases of patients reported by domestic and overseas papers from 1974 to 2021.
CHEN Qiong, FANG Jie, WEI Qianghua
core +1 more source
一例补体抑制剂治疗欠佳的再生障碍性贫血-阵发性睡眠性血红蛋白尿患者的多学科诊疗分析 [PDF]
一例青年男性患者诊断再生障碍性贫血伴阵发性睡眠性血红蛋白尿(paroxysmal nocturnal hemoglobinuria,PNH),经免疫抑制剂治疗后仅部分缓解。近1年贫血加重、输血依赖,考虑PNH活动性溶血所致,更换依库珠单抗治疗后贫血仍持续加重。详细询问病史发现患者慢性牙周感染,近1个月牙周疼痛溢脓伴发热。多学科讨论考虑慢性牙源性感染激活补体系统是PNH溶血加重的主要原因,急性感染影响了依库珠单抗的疗效。经多学科会诊制定治疗方案,给予静脉抗生素联合牙周冲洗、拔牙控制牙源性感染 ...
刘寅冬 +8 more
core +1 more source
骨髓涂片细胞形态学检查是诊断血液系统疾病最常用、最主要的方法,但由于易受到多种因素的干扰,骨髓涂片不能准确地指导临床诊断。骨髓活检和骨髓涂片在血液疾病的诊断中各具优缺点,而骨髓活检和骨髓涂片结合同步分析可弥补骨髓涂片检查的不足,能真实地反映骨髓造血细胞增生程度 ...
褚金龙, 邢桂芝, 李伟, 高彩凤
doaj
目的探讨骨髓涂片联合活检对骨髓增生异常综合征(MDS)诊断的价值。方法对43例MDS患者采用骨髓抽吸和活检进行取材,同步观察骨髓涂片和切片。结果活检中骨髓的增生程度明显高于涂片;涂片对红系病态造血的观察优于活检,而活检对原始细胞数量、骨髓基质、局部解剖定位、粒系、巨系病态造血观察优于涂片。结论骨髓涂片与骨髓活检在MDS的诊断、分型中各具优点,相互补充,联检可提高MDS诊断的准确性。
李芳, 白洁, 朴文花
doaj
目的探讨骨髓细胞形态与骨髓活检病理同步检测在血液病诊断与鉴别诊断中的价值。方法采用骨髓抽吸-活检双标本取材术,获取骨髓涂片、活检标本,对我院3374例血液病患者的血涂片、骨髓涂片与活检切片的细胞形态及病理变化进行比较研究。结果骨髓活检的增生度明显高于涂片 ...
杨娣娣 +6 more
doaj

