[A Review on Pathological High-risk Factors and Postoperative Adjuvant Chemotherapy in Stage IA Lung Adenocarcinoma]. [PDF]
早期非小细胞肺癌患者的生存率有待提高。含实体或微乳头成分、伴脉管侵犯或伴气道播散的浸润性腺癌患者属于复发风险高危人群,需要探索包括根治性手术切除在内的系统治疗方案。而现有指南不推荐IA期患者行术后辅助化疗。本文将综述上述病理高危因素在IA期肺腺癌患者中的研究进展以及辅助化疗在IA期复发风险高危人群中的作用。
Shen C, Fang W.
europepmc +2 more sources
[Research Progress on Risk Factors of Brain Metastasis in Non-small Cell Lung Cancer]. [PDF]
非小细胞肺癌(non-small cell lung cancer, NSCLC)脑转移是常见的治疗失败模式,发生脑转移的NSCLC患者中位生存时间仅为1个月-2个月。预防性脑照射(prophylactic cranial irradiation, PCI)可延缓脑转移的发生,但对NSCLC患者的生存获益仍存在争议,因此,通过预测脑转移的风险筛选可能从PCI中获益的人群尤为重要。本文就NSCLC脑转移的高危因素进行综述。
Sun S, Men Y, Hui Z.
europepmc +2 more sources
[Results of Lung Cancer Screening with Low-dose Computed Tomography and Exploration of Risk Factors in Guangzhou]. [PDF]
背景与目的 肺癌高居中国恶性肿瘤发病率和死亡率之首。既往肺癌筛查试验大多为针对吸烟者等高危人群的选择性筛查,然而亚洲肺癌病例非吸烟女性占相当比例。本研究旨在评估广州市社区女性的肺癌患病率并探究肺癌高危因素。 方法 采用胸部低剂量计算机断层扫描(low-dose computed tomography, LDCT)对广州市40-74岁女性居民行肺癌筛查,并根据2018版《中国肺癌低剂量螺旋CT筛查指南》对肺结节进行分类管理及计算阳性结节和肺癌检出率。筛查对象在行检查前均须完成“肺癌危险因素调研问卷 ...
Lu X +12 more
europepmc +2 more sources
Clinical study on high-risk factors for contralateral lymph node metastasis in unilateral papillary thyroid carcinoma [PDF]
Background and purpose: The occurrence of lymph node metastasis in papillary thyroid cancer (PTC) can have adverse effects on the prognosis of patients. This study aimed to investigate risk factors related to the occurrence of contralateral central lymph
YUAN Xinyue, YAO Yao, CHENG Shuai, ZHENG Xin, ZHANG Yuan
core +1 more source
目的 分析首次青年缺血性卒中患者出院、发病90d预后不良的相关危险因素。 方法 回顾性纳入18~45岁、发病72 h内的首次缺血性卒中患者,收集患者人口学信息、血管危险因素、实验室检查结果、入院和出院时NIHSS,以出院时和发病90 d mRS≥2分为预后不良,分别比较预后不良组和预后良好组危险因素的差异和病因分型特点,并采用多因素logistic回归分析出院和90 d预后不良的独立危险因素。 结果 研究共纳入691例首次青年缺血性卒中患者,出院预后不良234例(33.9%),90 ...
刘艳芳, 贾娇坤, 赵性泉
doaj +1 more source
New concept of de-escalation management strategy in breast cancer patients with 1-2 positive sentinel lymph nodes [PDF]
In the era of sentinel lymph node biopsy (SLNB), the axillary management concept that 1-2 positive sentinel lymph node (SLN) could safely omit axillary lymph node dissection (ALND) are gradually being accepted by more and more patients.
BI Zhao, WANG Yongsheng
core +1 more source
Associated Risk Factors in Group B Streptococcus Infection During Pregnancy [PDF]
BackgroundGroup B streptococcus (GBS) infection can give rise to intrauterine infection during pregnancy and postpartum endometritis, and increase the risk of premature birth or stillbirth.
HUANG Yan, WANG Mingying, FENG Junyan, ZHANG Jie
core +1 more source
The Value of Handheld COPD-6 Spirometry for Early COPD Detection in High Risk Elderly Population in Community [PDF]
BackgroundChronic obstructive pulmonary disease (COPD) is a common chronic disease of the respiratory tract, and lung function is necessary for the diagnosis of COPD.
XU Yunli, SHAO Hongtao, REN Xiaohong, LIU Lilan
core +1 more source
目的探讨双胎早产与单胎早产高危因素的特点以及单、双胎早产儿的结局。方法回顾性分析广州医科大学附属第三医院2009年1月至2015年12月的单、双胎孕产妇与新生儿临床数据资料。结果研究期间在该院分娩的36 931例新生儿,双胎2080例,单胎34 851例,其中早产5877例,双胎早产1395例(双胎早产组),早产率为67.07%;单胎早产4482例(单胎早产组),单胎早产率为12.86%,总计早产发生率为15.91%,双胎早产率明显高于单胎,差异有统计学意义(P22~26岁组、>26~30岁组、>30 ...
余波澜 +7 more
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Analysis of high risk factors of pathological escalation after LEEP in CIN2 diagnosed by colposcopic biopsy [PDF]
Objective To investigate the risk factors associated with pathological escalation to cervical intraepithelial neoplasia grade 2 (CIN2) or above (CIN2+) in patients with CIN2 confirmed by colposcopic biopsy, aiming to provide evidence for the stratified ...
Ma Xiaoli, Meng Ge, Duan Hua
core +1 more source

