Results 61 to 70 of about 10,357 (168)

Effects of hexabromocyclododecane (HBCD) on cardiac development in zebrafish embryos (Danio rerio): the mechanisms involved [PDF]

open access: yes, 2015
六溴环十二烷(1,2,5,6,9,10-Hexabromocyclododecane,HBCD)是被运用最广泛的阻燃剂之一,在全球的用量仅次于四溴双酚A和多溴联苯醚。HBCD具有持久性、生物累积性和生物放大效应,因而被定义为持久性有机污染物(persistentorganicpollutants,POPs)。已有研究表明HBCD具有发育毒性、神经毒性、内分泌毒性和生殖毒性,但对心脏发育毒性的研究十分有限,尤其缺乏对心脏发育毒性机制的研究。本研究以斑马鱼和H9C2细胞系为实验模型,采用低浓度HBCD(0 ...
吴美芳
core  

High-throughput sequencing analysis of deletion mutation of TRAPPC2 in an X-linked spondyloepiphyseal dysplasia tarda pedigree [PDF]

open access: yes
Objective·To explore the pathogenic gene and the mutation type of a family with X-linked spondyloepiphyseal dysplasia tarda (SEDT).Methods·Genomic DNA was extracted from the peripheral blood of 6 members of a SEDT family.
LIU Yu   +3 more
core   +1 more source

Diversity of bacterial community structure and its driving factors in three bays of Bohai Sea [PDF]

open access: yes, 2018
[Background] Sustainable development of coastal ecosystem has become one of the most important concerns for people nowadays. Riverine output and anthropogenic interrupt have important impacts on the coastal environment.
刘鹏远   +5 more
core   +2 more sources

Environmental niche models improve species identification in DNA barcoding

open access: yesMethods in Ecology and Evolution, Volume 15, Issue 12, Page 2343-2358, December 2024.
Abstract Recent advances in DNA barcoding have immeasurably advanced global biodiversity research in the last two decades. However, inherent limitations in barcode sequences, such as hybridization, introgression or incomplete lineage sorting can lead to misidentifications when relying solely on barcode sequences.
Cai‐qing Yang   +6 more
wiley   +1 more source

基于Relief F和灰色关联分析的高压断路器机械故障诊断

open access: yesGaoya dianqi, 2020
为提升高压断路器机械故障诊断算法故障诊断效率与精度,文中提出一种基于Relief F算法和灰色关联分析的故障诊断方法。首先,从高压断路器分合闸线圈电流中提取20种特征量,采用Relief F算法计算所有特征权重;然后,使用基于重要特征构成的故障样本建立灰色关联分析模型的参考序列,并归一化对应特征权重向量;最后,计算参考序列与待测序列之间的关联度值确定待测样本故障类型。通过实例分析验证结果表明,文中提出的诊断方法能准确诊断高压断路器机械故障,同时引入Relief F算法降低诊断模型复杂度并提高故障诊断效率,
李邦彦   +8 more
doaj  

MNK, IRR and FGFR genes in Haliotis diversicolor: molecular cloning, expression analysis and identification of SNPs associated with growth traits [PDF]

open access: yes, 2015
杂色鲍(Haliotisdiversicolor)是我国南方重要的养殖鲍种,研究与杂色鲍生长相关的基因,分析基因的表达规律,并筛查基因中与生长性状相关联的SNP位点,对于深入了解生长性状调控的分子机制,培育具有优良性状的新品种具有重要意义。本研究将MAPK互作激酶(MAPkinase-interactingkinase,MNK)、胰岛素相关多肽受体(Insulin-relatedpeptidereceptor,IRR)和成纤维细胞生长因子受体(Fibroblastgrowthfactorreceptor,
何佩茹
core  

Research on high-throughput detection of plasma cell-free DNA for targeted therapy-related genes screening and prognosis prediction in non-small cell lung cancer patients [PDF]

open access: yes
Background and purpose: High-throughput detection of plasma cell-free DNA (cfDNA) is widely used for multi-cancer targeted therapy drug screening, and this study investigated the relationship between the type and number of plasma cfDNA class Ⅰ and Ⅱ ...
DENG Qiling, SONG Di, XI Kexin, XIE Xiaoting, WU Xiaoyan, ZHAO Wei
core   +1 more source

Fetal lower urinary tract obstruction: international Delphi consensus on management and core outcome set

open access: yesUltrasound in Obstetrics &Gynecology, Volume 64, Issue 5, Page 635-650, November 2024.
ABSTRACT Objectives To reach an international expert consensus on the diagnosis, prognosis and management of fetal lower urinary tract obstruction (LUTO) by means of a Delphi procedure, and to use this to define a core outcome set (COS). Methods A three‐round Delphi procedure was conducted among an international panel of experts in fetal LUTO.
H. J. Mustafa   +90 more
wiley   +1 more source

Ecological Studies of Marine Virus and its Viral Lysate [PDF]

open access: yes, 2015
病毒是海洋生态系统中数量最多、多样性最为丰富的一类生命形式,具有极为重要的生态地位。为了深入认识海洋浮游病毒及其裂解浮游细菌释放的裂解产物的生态效应,本论文首先研究了西太平洋典型寡营养海区的浮游病毒对浮游细菌的致死效应;接着研究病毒裂解产物如何在不同营养水平(寡营养和富营养)特征的海洋水体中影响浮游细菌的生长、群落组成等生态特性。此外,本论文以海洋生态系统中一类生态地位非常重要的浮游细菌-玫瑰杆菌(Roseobacter)为研究对象,对其裂解性病毒进行了分离纯化和鉴定 ...
纪建达
core  

Gut microbiota dynamics of adult and sub‐adult sika deer during reintroduction 重引入过程中成年和亚成年梅花鹿肠道微生物的动态变化

open access: yesIntegrative Conservation, Volume 3, Issue 3, Page 257-270, September 2024.
Natural training enclosure design schematic. We selected 12 sika deer including six adults and six sub‐adults. Key considerations in the design of the natural training were to divide the training spatial ground into two parts (30 × 30 m small areas for isolation of new individuals and large areas measuring 200 × 600 m for free walking), and the ...
Wentao Zhang   +10 more
wiley   +1 more source

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