Results 81 to 90 of about 25,926,149 (268)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Revue des Sciences Humaines, 2017 ‘Pseudo-native speaker’ is the term given to a foreign language learner who has reached a high level of proficiency. Such level of proficiency is characterised by the mastery of grammar, vocabulary, and pronunciation.
Mohamed Akram Arabet
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Sesiidae of the Iberian Peninsula, new records and distributional analysis (Insecta: Lepidoptera)
SHILAP, 2014 Se presenta una lista comentada de la Sesiidae de la Península Ibérica. Synanthedon flaviventris (Staudinger, 1883) es nuevo para España y para la Península Ibérica, y S. scoliaeformis (Borkhausen, 1789) es nuevo para Portugal.
Z. Lastuvka, A. Lastuvka
doaj
eXPRESS Polymer LettersA set of linear Fischer-Tropsch (FT) waxes were oxidized to various degrees by utilizing an ozonolysis method. These waxes were comprehensively characterized in terms of their chemical composition, thermal behaviour, molecular weight distributions, and ...
Johannes Lodewiekus Barnard +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Revue des Sciences Humaines, 2019 We study the impact of introducing EST concepts for computer science learners through the use of translation. We have opted for the use of an on-the-fly translation, in which the teacher uses translation just to explain ambiguous terms or ideas related ...
Amer Draa
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Terapia afecţiunilor osteoarticulare degenerative la câine [PDF]
Medicamentul Veterinar, 2017 The degenerative joint disease, newly called osteoarthritis, is a common affection found in human and animal sectors. It is generally mentioned as a noninflammatory disease of articular cartilage the causes being represented by natural aging, traumas and
Bulai, Anca, Crivineanu, Maria
doaj