Results 241 to 250 of about 24,122,168 (308)

Synthesis, β-glucuronidase inhibition and molecular docking studies of hybrid bisindole-thiosemicarbazides analogs

Bioorganic Chemistry, 2016
Muhammad Taha, Nor Hadiani Ismail, Fazal Rahim   +2 more
exaly   +2 more sources

Gut microbiota profiles and fecal beta‐glucuronidase activity in kidney transplant recipients with and without post‐transplant diarrhea

Clinical Transplantation, 2021
Post‐transplant diarrhea is a common complication after solid organ transplantation and is frequently attributed to the widely prescribed immunosuppressant mycophenolate mofetil (MMF).
Lisa T. Zhang, L. Westblade, F. Iqbal, Michael R. Taylor, Alice Chung, M. Satlin, Matthew Magruder, E. Edusei, S. Albakry, Brittany Botticelli, Amy E. Robertson, Tricia Alston, D. Dadhania, M. Lubetzky, S. Hirota, S. Greenway, J. Lee   +16 more
semanticscholar   +1 more source

Beta-Glucuronidase Inhibition by Constituents of Mulberry Bark

Planta Medica, 2021
Intestinal bacterial β-glucuronidases, the key enzymes responsible for the hydrolysis of various glucuronides into free aglycone, have been recognized as key targets for treating various intestinal diseases. This study aimed to investigate the inhibitory
Yue Bai, Lu Chen, Yun-feng Cao, Xu-Dong Hou, Shouning Jia, Qi Zhou, Yu-qi He, Jie Hou   +7 more
semanticscholar   +1 more source

ATHEROSCLEROSIS AND BETA-GLUCURONIDASE

Lancet, The, 1960
exaly   +3 more sources

The study of inhibitory effect of natural flavonoids toward β-glucuronidase and interaction of flavonoids with β-glucuronidase.

International Journal of Biological Macromolecules, 2019
β-Glucuronidase plays a vital role in the metabolism of drug and endogenous substance. Herein, we assayed the inhibitory effects of thirty-six flavonoids (1-36) toward β-glucuronidase (Escherichia coli) using the probe reaction of DDAO-glu hydrolysis ...
Chengpeng Sun, Jian-Kun Yan, Jing Yi, Xin-Yue Zhang, Zhen-long Yu, Xiaokui Huo, Jia-Hao Liang, Jing Ning, Lei Feng, Chao Wang, Bao-jing Zhang, Xiangge Tian, Lin Zhang, Xiaochi Ma   +13 more
semanticscholar   +1 more source

Deciphering molecular mechanisms underlying the inhibition of β-glucuronidase by xanthones from Centaurium spicatum.

Bioorganic chemistry (Print)
Herein, we scrutinized the inhibitory potential of five xanthones and a flavonoid, sourced from Centaurium spicatum, against β-glucuronidase activity.
Emadeldin M. Kamel, H. Alqhtani, M. Bin-Jumah, H. Rudayni, A. El-Bassuony, Al Mokhtar Lamsabhi   +5 more
semanticscholar   +1 more source

Bridging in silico and in vitro perspectives to unravel molecular mechanisms underlying the inhibition of β-glucuronidase by coumarins from Hibiscus trionum.

Biophysical Chemistry
Unraveling the intricacies of β-glucuronidase inhibition is pivotal for developing effective strategies in applications specific to gastrointestinal health and drug metabolism.
Emadeldin M. Kamel, Faris F. Aba Alkhayl, H. Alqhtani, M. Bin-Jumah, H. Rudayni, Al Mokhtar Lamsabhi   +5 more
semanticscholar   +1 more source

Strategy for effective inhibition of arylsulfatase/β-glucuronidase to prevent deconjugation of sulfate and glucuronide conjugates in wastewater during sample collection and storage.

Science of the Total Environment, 2019
Arylsulfatase and β-glucuronidase are two important enzymes that are responsible for deconjugation of estrogen conjugates. It is important to keep estrogen conjugates intact during sample collection and storage, while the effective inhibition conditions ...
Jun Zhang, Ze-hua Liu, Shu-shu Zhong, Hao Wang, Bamu Caidan, Hua Yin, Z. Dang   +6 more
semanticscholar   +1 more source

Prenylflavonoids sanggenon C and kuwanon G from mulberry (Morus alba L.) as potent broad-spectrum bacterial β-glucuronidase inhibitors: Biological evaluation and molecular docking studies

Journal of Functional Foods, 2018
Gut microbial β-glucuronidases show varied substrate specificity and inhibition propensity, highlighting the necessity of discovering broad-spectrum β-glucuronidase inhibitor to meet clinical needs.
Bin Wei, Wei Yang, Zhixiang Yan, Qing-Wen Zhang, Ru Yan   +4 more
semanticscholar   +1 more source

Beta glucuronidase short‐term immunotherapy

Allergy, 2003
[No abstract available]
Di Stanislao C., ANGELINI, FEDERICA, Gagliardi M. C., Di Bernardino L., Fundaro' C., Galli E., ROSSI, PAOLO   +6 more
openaire   +3 more sources