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The Role of Gut Microbial β-Glucuronidase in Estrogen Reactivation and Breast Cancer [PDF]
Frontiers in Cell and Developmental Biology, 2021 Over the past decade, the gut microbiota has received considerable attention for its interactions with the host. Microbial β-glucuronidase generated by this community has hence aroused concern for its biotransformation activity to a wide range of ...
Yue Sui +3 more
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Molecules, 2019 β-glucuronidase is a lysosomal glycosidase enzyme which catalyzes the extracellular matrix of cancer and normal cells and the glycosaminoglycans of the cell membrane, which is important for cancer cell proliferation, invasion, and metastasis.
El Hassane Anouar +9 more
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Breast milk beta-glucuronidase levels in hyperbilirubinemia
The Turkish Journal of Pediatrics, 2001 Breast milk beta-glucuronidase was thought to be one of the etiological factors in the pathogenesis of late-onset breast-milk jaundice, but results of these studies are conflicting.
S Yiğit, G Ciliv, C Aygün, G Erdem
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The gut microbiome and drug-resistant epilepsy: Microbiome-antiseizure medication interactions and implications for pharmacoresistance. [PDF]
Epilepsia OpenAbstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Zammar K +4 more
europepmc +2 more sources
한국균학회지, 2022 We aimed to produce a potent β-glucuronidase inhibitor from wild yeast that could inactivate toxic substances in the colon. Culture supernatants and cell-free extracts of non-pathogenic wild yeasts were prepared and their β-glucuronidase inhibitory ...
Seon-Jeong Park, Jong-Soo Lee
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Gut Microbes, 2022 The intestinal microbiota produces β-glucuronidase that plays an essential role in the metabolism of the immunosuppressant mycophenolate mofetil (MMF). This drug is commonly used in organ and hematopoietic cell transplantation (HCT), with variations in ...
Mohammad Haneef Khan +7 more
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Toxins, 2020 Deoxynivalenol is one of the most ubiquitous mycotoxins in the Western diet through its presence in cereals and cereal products. A vast amount of studies indicate the worrying level of exposure to this toxin, while even high percentages of the population
Arnau Vidal +3 more
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Applied Sciences, 2022 We isolated eight known secondary metabolites, including two isocoumarins and six coumarins, from the stems and branches of Acer mono Maxim. Their structures were confirmed using nuclear magnetic resonance spectroscopy and by comparing the data to ...
Nguyen Viet Phong +3 more
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Comparison of Salivary Beta Glucuronidase Activity in Chronic Periodontitis Patients with and without Diabetes Mellitus [PDF]
Journal of Clinical and Diagnostic Research, 2014 Aim of the study: The aim of the study was to estimate the salivary beta glucuronidase (β) activity in patients with chronic periodontitis with and without diabetes mellitus and to evaluate the relationship between Beta Glucuronidase activity and ...
Jaiganesh Ramamurthy +2 more
doaj +1 more source
, 1952 1) A method has been devised for the purification of ox liver beta-glucuronidase utilising the interactions of proteins with metallic ions and organic solvents. An 800 fold purification has been achieved by such means with a 5% recovery of the enzyme. 2)
Smith, Evelyn Elizabeth Brown
core +3 more sources