Results 131 to 140 of about 334,832,769 (318)
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Reduction of total harmonic distortion in power inverters [PDF]
The output voltage of PWM power inverters shows harmonic distortion due to several causes; the main ones are the modulation algorithm, nonlinearities in the output filter, dead times, voltage drops across the switches and modulation of the dc bus voltage.
Aymonino, Oscar Andres +3 more
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Nematic order in a simple-cubic lattice-spin model with full-ranged dipolar interactions
In a previous paper [Phys. Rev. E 90, 022506 (2014)], we had studied thermodynamic and structural properties of a three-dimensional simple-cubic lattice model with dipolar-like interaction, truncated at nearest-neighbor separation, for which the ...
Chamati, Hassan, Romano, Silvano
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Additivity properties of a Gaussian Channel
The Amosov-Holevo-Werner conjecture implies the additivity of the minimum Re'nyi entropies at the output of a channel. The conjecture is proven true for all Re'nyi entropies of integer order greater than two in a class of Gaussian bosonic channel where ...
A. S. Holevo +9 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
تلقي رثاء ابن العسَّال لطليطلة بين التفهم والإنكار
تعدّ نظرية التلقي من أهمّ النظريات التي اهتمت بالمتلقّي، ودوره الداعم لعملية الإبداع في الشِّعر بخاصّة. ومن بين النّصوص الشِّعرية التي حظيت باهتمام الدارسين والنقّاد أبيات ابن العسّال التي نظمها في رثاء طليطلة، فقد كانت في مستوى البرقية المزلزلة وجّهها ...
مليكة حيمر +1 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

