Results 131 to 140 of about 284,135,228 (316)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Occurrence of the Lapland Longspur (Calcarius lapponicus) in Mid-Winter in Massachusetts
Volume: 19Start Page: 202End Page ...
Townsend, Charles Wendell,
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Fur Trade and the Fur Supply
Volume: 3Start Page: 1End Page:
Ashbrook, F. G.
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
تلقي رثاء ابن العسَّال لطليطلة بين التفهم والإنكار
تعدّ نظرية التلقي من أهمّ النظريات التي اهتمت بالمتلقّي، ودوره الداعم لعملية الإبداع في الشِّعر بخاصّة. ومن بين النّصوص الشِّعرية التي حظيت باهتمام الدارسين والنقّاد أبيات ابن العسّال التي نظمها في رثاء طليطلة، فقد كانت في مستوى البرقية المزلزلة وجّهها ...
مليكة حيمر +1 more
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Stone\u27s \u27The Birds of New Jersey\u27
Volume: 27Start Page: 95End Page ...
Stone, Witmer.
core +1 more source

