Results 41 to 50 of about 10,486,500 (294)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
EOS Science Poster Series: LAND- Our Changing Earth [PDF]
, 2007 This poster, one in a four-part series, highlights recent images from select NASA Earth Science spacecraft and showcases related research results. The back gives a brief overview of the science and missions behind NASA's study of LAND. Educational levels:
core
Bringing the Field into the Classroom by Using Dynamic Digital Maps to Engage Undergraduate Students in Petrology Research [PDF]
, 2004 This article describes the use of Dynamic Digital Maps (DDMs) in undergraduate petrology courses. A DDM is a stand-alone computer program that presents interactive geologic maps, digital images, movies, animations, text and data.
Christopher Condit, Theresa Boundy
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Developing Effective K-16 Geoscience Partnerships [PDF]
, 2003 This article describes the benefits of research partnerships to scientists, students, and teachers. There is growing awareness that the way science is experienced in the K-16 classroom deviates greatly from the experiences of practicing researchers ...
Paul Harnik, Robert Ross
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Space Math: Solar Storms and You! Exploring Satellite Design [PDF]
, 2000 This educator’s guide includes activities in space science.
Sten Odenwald
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Vojnotehnički Glasnik, 2007 U radu se iznose iskustva pri izradi i oblikovanju vojne topografske karte razmera 1: 250 000. Karta se izrađuje u Vojnogeografskom institutu, po NATO standardima i u digitalnom obliku.
Mirko Borisov
doaj +1 more source