Results 51 to 60 of about 36,537 (194)

КІЛЬКІСНА ХАРАКТЕРИСТИКА ВЛАСНИХ НАЗВ МАТЕРІАЛЬНИХ ОБ’ЄКТІВ

Записки з українського мовознавства, 2019
У статті з’ясовано, що загальна кількість прагматонімів становить 2 006 000, проте лише 70 000 можуть функціонувати як одиниці мови. Найбільше засвідчено власних назв будинків і подібних споруд (1 260 000), товарів (300 000) і окремих предметів (260 000).
М. М. Торчинський
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Trend of disease burden of dengue fever in the population < 20 years old in China from 1990 to 2021: an analysis based on data from GBD 2021

Zhongguo gonggong weisheng
ObjectiveTo understand the trend of disease burden of dengue fever in the population < 20 years old in China from 1990 to 2021 and provide scientific evidence for the development of targeted prevention and control policies.
Qian ZHANG, Yunfei XU, Mengxiao HUANG, Jiacheng LI, Junqing ZHANG   +4 more
doaj   +1 more source

Interpretation of cancer death burden data from disease surveillance sites in China from 2005 to 2020 [PDF]

Zhenduanxue lilun yu shijian
In December 2023, the Chinese Center for Disease Control and Prevention published National and subnational trends in cancer burden in China, 2005-2020: an analysis of national mortality surveillance data.on Lancet Public Health, covering the mortality ...
ZHANG Xin, ZHENG Ying
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Calculo de tanque de PRFV de 200 000 litros de capacidad. // 200 000 liters capacity PRFV tank calculation.

Ingeniería Mecánica, 2002
La tarea que se acomete es el cálculo a resistencia y rigidez de un tanque para el almacenamiento de agua, de 200 000 litrosde capacidad, construido de plástico reforzado con fibras de vidrio, PRFV. El mismo es cilíndrico vertical, de 8 metros dediámetro
J. García de la Figal Costales, O. Frías   +1 more
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

DIE STIGTING EN WERKSAAMHEDE VAN DIE "NEDERLANDSCH BIJSTANDSFONDS VOOR ZUID-AFRIKA" (1900-1903)

Scientia Militaria, 2012
Die Tweede Anglo-Boereoorlog (1899 - 1902) het byna drie jaor gewoed. Die Britsemilitêre verliese is, afgerond, op ongeveer 7 000 gesneuweldes en 20 000 gewondes geskat, Die republikeinse militêre verliese word op ongeveer 4 000 gesneuweldes bereken. Die
Jan Ploeger
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source