Results 41 to 50 of about 1,199,516 (242)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Lithuanian unpublished interwar topographical maps
Geodesy and Cartography, 2012 A number of publications about Lithuanian interwar topographical mapping present the same piece of information that until the beginning of the World War II only the following maps were published: 92 M 1:25 000 and 44 M 1:100 000. The article analyses the
Romualdas Girkus +1 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Russie d'Asie 1:2 000 000. [4], Kazan
, 1923 Échelle(s) : 1:2 000 ...
France. Service géographique de l'armée. Cartographe
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Comparación de las metodologías VIZIR y PCI en la evaluación de tramos de pavimento de las vías Manizales-Chinchiná (PR 30+000-PR 44+000 y variante Santa Rosa de Cabal (PR 00+000-PR 03+000) [PDF]
, 2005 En el presente trabajo se encuentra la evaluación de la condición del pavimento, realizada sobre dos tramos diferentes de vía, uno en la vía Manizales-Chinchiná comprendido entre los kilómetros PR39+000 al PR44+000 y en la variante Santa Rosa de Cabal ...
Dussán Medina, Javier Ernesto +1 more
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The global burden of tuberculosis mortality in children: a mathematical modelling study
The Lancet Global Health, 2017 Background: Tuberculosis in children is increasingly recognised as an important component of the global tuberculosis burden, with an estimated 1 million cases in 2015.
Dr Peter J Dodd, PhD +4 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Russie d'Asie 1:2 000 000. [8], Krasnoiarsk
, 1918 Échelle(s) : 1:2 000 000Appartient à l’ensemble documentaire ...
France. Service géographique de l'armée. Cartographe
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