Results 171 to 180 of about 260,485 (262)

Hemolytic Uremic Syndrome Outbreak in Adults and Shiga Toxin-Producing Escherichia coli Negative for Locus of Enterocyte Effacement, France, 2025. [PDF]

Emerg Infect Dis
de Larminat J, La K, Bidet P, Birgy A, Liguori S, Phlipaux P, Courroux C, Crombé F, Blanco J, Coppo P, Dossier A, Armand-Lefevre L, Weill FX, Nodari CS, Jones G, Cointe A, Bonacorsi S.   +16 more
europepmc   +1 more source

Impact of cumulative glucocorticoid exposure on vancomycin clearance in hospitalized children: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Prior glucocorticoid exposure is associated with modestly increased vancomycin clearance in hospitalized children, partly mediated by renal function and inflammation and may contribute to subtherapeutic early drug exposure. Abstract Introduction Augmented renal clearance (ARC) can lead to subtherapeutic vancomycin exposure in children.
Kouki Tomari, Ruud H. J. Verstegen, Cintia Cruz, Erin Chung, Aleena Azim, Shinya Ito, Tamorah R. Lewis   +6 more
wiley   +1 more source

Antisense oligonucleotide targeting TARDBP-EGFR splicing axis inhibits progression of oral squamous cell carcinoma through ABCA1-regulated cholesterol efflux. [PDF]

Int J Oral Sci
Ni N, Wang M, Yuan Z, Zhang L, Cai J, Du Q, Li P, Gao C, Zhang H, Li Y, Yuan H.   +10 more
europepmc   +1 more source

The quantification and epistemology of medicines use and polypharmacy tested in an observational study

British Journal of Clinical Pharmacology, EarlyView.
Definitions of ‘medicines use’ and ‘polypharmacy’ may refer to all medicines, regular long‐term medicines or another subset. Valid definitions of medicines use should incorporate type of use (long term, short course and as needed [PRN]), changes in use (start, stop and dose change) and a description of temporal examination (cross‐sectional or ...
Lorna Pairman, Paul Chin, Matthew Doogue
wiley   +1 more source

Pixel level anomaly detection in second harmonic generation microscopy for non destructive defect inspection of AlGaN/GaN heterostructures. [PDF]

Discov Nano
Kang CF, Hung CC, Huang CH, Li TC, Uen WY, Chiu CH.   +5 more
europepmc   +1 more source

Relationships among nitrous oxide exposure, neurological injury and biomarkers

British Journal of Clinical Pharmacology, EarlyView.
Aims Recreational nitrous oxide (N2O) misuse is an increasing public health problem associated with functional cobalamin (B12) deficiency and severe neurological complications. Despite growing recognition of its harms, the dose–response relationship and clinical value of biomarkers remain unclear.
Laxna Bhujel, Angela L. Chiew, Bhashita Jagarlamudi, Pramod Chandru, Naren Gunja, Nancy Briggs, Betty S. Chan   +6 more
wiley   +1 more source

The draft genome sequence of <i>Kitasatospora</i> sp. HPM-01-4 isolated from Mentaos Pine Forest, heart of Borneo, Indonesia. [PDF]

Microbiol Resour Announc
Ariyanti D, Nuhamunada M, Izzati N, Fitriana M, Widyaningrum AR, Sanka I, Kusuma AB.   +6 more
europepmc   +1 more source

Trends in publicly subsidized and private access to GLP‐1 medicines indicated for type 2 diabetes in Australia, 2020–2025

British Journal of Clinical Pharmacology, EarlyView.
Aims GLP‐1 medicines provide substantial cardio‐renal benefits for type 2 diabetes (T2D) and are increasingly used for weight loss. Most high‐income countries subsidize access for T2D with restrictions; use outside of these restrictions occurs through private prescriptions. Despite strong consumer demand, the extent of private access to GLP‐1 medicines
Michael O. Falster, Juliana de Oliveira Costa, Tamara Y. Milder, Joanne Carson, Cade Shadbolt, Brendon L. Neuen, Clare Arnott, Andrew Wilson, Min Jun, Nicole Pratt, Sallie‐Anne Pearson   +10 more
wiley   +1 more source

Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

British Journal of Clinical Pharmacology, EarlyView.
Dolutegravir underpins modern first‐ and second‐line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the pharmacogenomics of dolutegravir, focusing on pharmacokinetics and pharmacodynamics, and methodological limitations ...
Ronald Kiguba, Mishael Ssesanga, Munir Pirmohamed   +2 more
wiley   +1 more source

Herpes Simplex Virus 1 in Trigeminal Ganglia of Trafficked Neotropical Primates, Peru, 2024. [PDF]

Emerg Infect Dis
Vilchez-Delgado F, Zhou L, O'Connor S, Colan R, Escobar-Mendoza L, Mendoza AP, Ghersi BM, Andrade R, Talledo-Albújar M, Rosenbaum MH.   +9 more
europepmc   +1 more source