Results 191 to 200 of about 290,486 (231)

The quantification and epistemology of medicines use and polypharmacy tested in an observational study

British Journal of Clinical Pharmacology, EarlyView.
Definitions of ‘medicines use’ and ‘polypharmacy’ may refer to all medicines, regular long‐term medicines or another subset. Valid definitions of medicines use should incorporate type of use (long term, short course and as needed [PRN]), changes in use (start, stop and dose change) and a description of temporal examination (cross‐sectional or ...
Lorna Pairman, Paul Chin, Matthew Doogue
wiley   +1 more source

Relationships among nitrous oxide exposure, neurological injury and biomarkers

British Journal of Clinical Pharmacology, EarlyView.
Aims Recreational nitrous oxide (N2O) misuse is an increasing public health problem associated with functional cobalamin (B12) deficiency and severe neurological complications. Despite growing recognition of its harms, the dose–response relationship and clinical value of biomarkers remain unclear.
Laxna Bhujel, Angela L. Chiew, Bhashita Jagarlamudi, Pramod Chandru, Naren Gunja, Nancy Briggs, Betty S. Chan   +6 more
wiley   +1 more source

Trends in publicly subsidized and private access to GLP‐1 medicines indicated for type 2 diabetes in Australia, 2020–2025

British Journal of Clinical Pharmacology, EarlyView.
Aims GLP‐1 medicines provide substantial cardio‐renal benefits for type 2 diabetes (T2D) and are increasingly used for weight loss. Most high‐income countries subsidize access for T2D with restrictions; use outside of these restrictions occurs through private prescriptions. Despite strong consumer demand, the extent of private access to GLP‐1 medicines
Michael O. Falster, Juliana de Oliveira Costa, Tamara Y. Milder, Joanne Carson, Cade Shadbolt, Brendon L. Neuen, Clare Arnott, Andrew Wilson, Min Jun, Nicole Pratt, Sallie‐Anne Pearson   +10 more
wiley   +1 more source

Anisotropic Structural Response of NdGaO₃ Single Crystals to 147 MeV Kr-Ion Irradiation. [PDF]

Materials (Basel)
Karipbayev ZT, Tokasheva MS, Bakytkyzy A, Zhunusbekov AM, Kakimov A, Konuhova M, Konuhova S, Bezrukovs V, Popov AI.   +8 more
europepmc   +1 more source

Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

British Journal of Clinical Pharmacology, EarlyView.
Dolutegravir underpins modern first‐ and second‐line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the pharmacogenomics of dolutegravir, focusing on pharmacokinetics and pharmacodynamics, and methodological limitations ...
Ronald Kiguba, Mishael Ssesanga, Munir Pirmohamed   +2 more
wiley   +1 more source

Programmable three‐state nanoreactor for spatiotemporally controlled tumor therapy

BMEMat, EarlyView.
The OMVs are shielded with a biocompatible Da–Ca shell, which prolongs its circulation period and promotes intratumoral accumulation. Importantly, the biocompatible Da–Ca shell can be controllably disintegrated in tumor microenvironment by using laser irradiation, generating in situ hyperthermia and releasing Ca2+.
Guihong Lu, Peng Ye, Xiaoyan Li, Ke Ma, Chengliang Lyu, Kai Zhang, Ran Luo, Yang Ji, Shiqi Mei, Fan Zhang, Jinxie Zhang, Lin Mei, Hui Tan   +12 more
wiley   +1 more source

A global investigation of the Moral Incongruence Model of Pornography Use across genders, religions, and cultures. [PDF]

J Behav Addict
Bőthe B, Michaud A, Beaulieu V, Houle S, Nagy L, Koós M, Kraus SW, Potenza MN, Demetrovics Z, Költő A, International Sex Survey Consortium, Grubbs JB.   +11 more
europepmc   +1 more source

Knowledge Sharing in the Mining Sector: Unlocking Employee Ambidexterity Through Psychological and Environmental Mediating Factors

Business Strategy and the Environment, EarlyView.
ABSTRACT This study examines how and why individual knowledge sharing fosters ambidextrous behavior among nonmanagerial employees in an operationally intensive, environmentally sensitive industry. We conducted a survey of 243 operators across 10 plants of an international lime producer, finding that knowledge sharing is positively related to individual
Laurent Scaringella, William Limousin, Morgane Scaringella   +2 more
wiley   +1 more source

WHO estimates of the global, regional, and national burden of 42 foodborne infectious and chemical hazards, 2000-21: an updated data synthesis. [PDF]

Lancet Glob Health
Lake RJ, Devleesschauwer B, Majowicz SE, Robertson LJ, Jakobsen LS, Agudo A, Pires SM, Kirk MD, Walter ES, Keddy KH, di Bari C, Vaes L, Havelaar AH, Roberts C, Gobena T, Kretzschmar ME, Nane GF, Hoffmann S, Mughini-Gras L, Sripa B, Kubota K, Founou LL, Bai L, Huthiel MA, Rachmawati T, Estrada-Garcia T, Kumar A, Natour FA, Jaffee S, Henson S, Ingenbleek L, Kumapley R, Borghi E, Minato Y, WHO Foodborne Disease Burden Epidemiology Reference Group for 2021–25.   +34 more
europepmc   +1 more source

The Synthesis Effects on the Performance of P2‐Na0.6Li0.27Mn0.73O2 Cathode Material for Sodium‐Ion Batteries

Battery Energy, Volume 4, Issue 2, March 2025.
The effect of reagents on the structure and performance of sodium‐layered oxides has not yet been thoroughly studied. This work explored this factor systematically through in situ high‐temperature XRD. The samples synthesized via MnCO3‐based precursors form the Li2MnO3 phase at evaluated temperature and perform better than those through MnO2‐based ...
Cuihong Zeng, Ziqin Zhang, Jiming Peng, Jia Qiao, Qichang Pan, Fenghua Zheng, Youguo Huang, Hongqiang Wang, Qingyu Li, Sijiang Hu   +9 more
wiley   +1 more source