GluN2A-NMDA receptor inhibition disinhibits the prefrontal cortex, reduces forced swim immobility, and impairs sensorimotor gating. [PDF]
Dong YP +15 more
europepmc +1 more source
Abstract Objective Conceptualizing functional/dissociative seizures (FDS) as resulting from dissociation, or conversion, we hypothesized that, compared to epileptic seizures (ES), FDS should carry more symbolic or communicative content and that this would allow observers to distinguish FDS from ES.
Nayrin Dissouky +8 more
wiley +1 more source
Food insecurity, food assistance, and physical and cognitive functioning among older Americans. [PDF]
Dhakal U, El Asmar K, Mendes deLeon CF.
europepmc +1 more source
Depressive symptoms as independent correlates of epilepsy‐related cognitive burden
Abstract Objective This study was undertaken to assess the relationship between the severity of depression and anxiety symptoms and epilepsy‐related variables and cognitive burden in people with epilepsy (PwE), as assessed using EpiTrack. Methods We prospectively enrolled a cohort of PwE who underwent EpiTrack and evaluation by Generalized Anxiety ...
Biagio Maria Sancetta +10 more
wiley +1 more source
Abstract Objective The thalamus is a key hub in seizure propagation, and its nuclei are emerging targets for neuromodulation. However, the contributions of individual nuclei to epileptic networks remain unclear, particularly in children, who are less studied than adults.
Xiyu Feng +11 more
wiley +1 more source
Abstract Objective Posttraumatic stress disorder (PTSD) is more prevalent in epilepsy than in the general population. However, it remains unclear whether this association is specific to epilepsy or a broader consequence of experiencing unpredictable acute episodes within chronic diseases.
Lisa‐Dounia Soncin +9 more
wiley +1 more source
Acceptance of weight loss medication in patients with atypical hyperplasia or carcinoma of the endometrium as part of the fertility preservation treatment: A qualitative study. [PDF]
Adeoye OO +4 more
europepmc +1 more source
Are seizure forecasts and cycles better than chance? What chance?
Abstract Objective There is a growing synergy between the lines of research on cycles in epilepsy and seizure forecasting. It has been conjectured, for instance, that incorporating information about significant seizure cycles into forecasting algorithms can lead to a better‐than‐chance forecasting performance.
Ralph G. Andrzejak +4 more
wiley +1 more source
Fronto-caudate and callosal microstructural alterations: unveiling multimodal MRI biomarkers in early Parkinson's disease. [PDF]
Bernabéu-Sanz Á +3 more
europepmc +1 more source
Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome
Overview of the phase 3 trial evaluating soticlestat as adjunctive therapy in children and young adults with Dravet syndrome. Abstract Objective This study evaluated the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in children and young adults with Dravet syndrome (DS).
Joseph Sullivan +14 more
wiley +1 more source

