Results 261 to 270 of about 1,398,610 (367)

Synchrotron‐generated microbeams as a radiosurgical alternative for drug‐resistant epilepsies: Proof of concept in a mouse model of mesiotemporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective One‐third of patients with epilepsy, particularly those with mesial temporal lobe epilepsy (MTLE), remain resistant to medication. Resective surgery, the gold standard, is highly invasive and carries significant risks. Here, using a mouse model, we explored the potential of microbeam radiation therapy (MRT), a new technique based on ...
Loan Samalens, Camille Beets, Clothilde Courivaud, Sarvenaz Keshmiri, Jean‐François Adam, Paolo Pellicioli, Emmanuel Luc Barbier, Raphaël Serduc, Antoine Depaulis   +8 more
wiley   +1 more source

Are single‐item global rating scales the same, better, or worse than multi‐item scales in epilepsy: A scoping review and meta‐analysis

Epilepsia, EarlyView.
Abstract Objective To examine the performance of single‐item global ratings (SIGRs) and multi‐item scales (MISs) in epilepsy research, and assess the influence of diverse constructs, study designs, and statistical methods. Methods Systematic scoping review following Preferred Reporting Items for Systematic reviews and Meta‐Analyses (PRISMA) and Joanna ...
Ann Subota, Mandavi Kashyap, Samuel Wiebe   +2 more
wiley   +1 more source

Regulation of the mechanoresponsive Neat1 and PSPC1 by substrate stiffness in TGF-β1-induced renal progenitor cell fate. [PDF]

J Biomed Sci
Huang HN, Lee LW, Kuo CH, Wong TY, Chiu WT, Tang MJ.   +5 more
europepmc   +1 more source

Weaning from ketogenic diet therapy in children with epilepsy: Insights from a retrospective study

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to describe weaning practices following ketogenic diet therapy (KDT) in children with epilepsy and to identify clinical factors associated with seizure exacerbation or antiseizure medication adjustments during or after weaning from KDT.
Noémie Donnard, Blandine Dozières‐Puyravel, Katia Geraldes, Céline Perrot, Virginie Quéméner, Estelle Goujon, Pierre Truchy, Hala Nasser, François‐Xavier Mauvais, Marion Danse, Stéphane Auvin   +10 more
wiley   +1 more source

Dual block evidence of the effects of topiramate, a sulfamate-substituted monosaccharide, on voltage-gated sodium current and hyperpolarization-activated cation current. [PDF]

BMC Pharmacol Toxicol
Tzeng RC, Lai MC, Wu SN, Huang CW.
europepmc   +1 more source

Sex‐specific elevated incidence of glaucoma associated with topiramate versus valproate or lamotrigine in epilepsy, not migraine: A population‐based cohort study

Epilepsia, EarlyView.
Abstract Objective Topiramate has been linked to increased glaucoma risk, potentially through mechanisms involving ocular fluid shifts. However, comparative risks vs other antiseizure medications (ASMs) and variation by sex or indication remain uncertain.
Cuiling Wei, Rachel Yui Ki Chu, Rachel Lancey Lai, Florinda Hui‐Ning Chu, Ian Yu Hin Leung, William Chun Yin Leung, Franco Wing Tak Cheng, Thomas Chi Ho Lam, Ian Chi Kei Wong, Esther Wai Yin Chan, Francisco Tsz Tsun Lai   +10 more
wiley   +1 more source

Air-coupled piezoelectric micromachined ultrasonic transducer array based on low-cost and large remnant polarization PZT thin film. [PDF]

Sci Rep
Lin JL, Liu YH, Kao CL, Wu SW, Hsu HJ, Lin HC, Li CY, Chen CY, Wang YH, Huang CH.   +9 more
europepmc   +1 more source

Memantine treatment in individuals with GRIN gain‐of‐function variants is associated with improvements in behavior, development, and seizure frequency

Epilepsia, EarlyView.
Abstract Objective GRIN‐related disorders due to pathogenic variants in GRIN1, GRIN2A, GRIN2B, or GRIN2D genes are associated with altered N‐methyl‐D‐aspartate receptor (NMDAR) function. Functional changes include gain (GoF) and loss of receptor function (LoF). Clinical reports describing the use of the NMDAR blocker memantine in GRIN‐related disorders
Maike Karnstedt, Riley E. Perszyk, Scott J. Myers, Ellington McDaniels, Marta Somorai, Ingo Borggraefe, Danielle C. M. Veenma, An‐Sofie Schoonjans, Pasquale Striano, Tadeu A. Fantaneanu, Steffen Syrbe, Kristen Park, Wenjuan Chen, Hongjie Yuan, Stephen F. Traynelis, Timothy A. Benke, Johannes R. Lemke, Ilona Krey   +17 more
wiley   +1 more source

Correction: Severe enterovirus A71 pathogenesis and immune responses in human nucleolin transgenic mice. [PDF]

Med Microbiol Immunol
Hsiao NE, Wang YF, Lin YC, Chou WT, Hsu LJ, Wang SM, Wang JR, Lai MD, Chen SH, Chang CF.   +9 more
europepmc   +1 more source

Seizure control after radiosurgical treatment in patients with cerebral arteriovenous malformations: An observational study

Epilepsia, EarlyView.
Abstract Objective Seizures are among the most common symptoms of cerebral arteriovenous malformations (AVMs). Although the main goal of AVM treatment remains complete obliteration, seizure control has become an important treatment aspect in recent years.
Philip Lederer, Muhammet Dogan, Dorian Hirschmann, Beate Kranawetter, Anna Cho, Philipp Goebl, Christian Dorfer, Brigitte Gatterbauer, Karl Rössler, Philippe Dodier, Wei‐Te Wang, Gerhard Bavinzski, Arthur Hosmann, Wolfgang Serles, Josa M. Frischer   +14 more
wiley   +1 more source