Results 1 to 10 of about 1,828,698 (329)

Identifying the counterpart of HESS J1858+020 [PDF]

Astronomy and Astrophysics, 2009
6 pages, 3 figures, accepted for publication in A&A ...
S. Parón, E. Giacani
openalex   +5 more sources

Efficient one-pot radiosynthesis of the ¹¹C-labeled aquaporin-4 inhibitor TGN-020. [PDF]

EJNMMI Radiopharm Chem
Background [11C]TGN-020 has been developed as a positron emission tomography (PET) tracer for imaging aquaporin-4 (AQP4) in the brain and used in clinical studies.
Kawamura K, Kumata K, Yamasaki T, Ogawa M, Kurihara Y, Nengaki N, Nakamura Y, Ono M, Takado Y, Igarashi H, Zhang MR.   +10 more
europepmc   +2 more sources

Acutely Inhibiting AQP4 With TGN-020 Improves Functional Outcome by Attenuating Edema and Peri-Infarct Astrogliosis After Cerebral Ischemia

Frontiers in Immunology, 2022
BackgroundIschemic stroke is one of the leading causes of human death and disability. Brain edema and peri-infarct astrocyte reactivity are crucial pathological changes, both involving aquaporin-4 (AQP4).
Chengfeng Sun, Luyi Lin, Lekang Yin, Xiaozhu Hao, Jiaqi Tian, Xiaoxue Zhang, Yan Ren, Chanchan Li, Yanmei Yang   +8 more
doaj   +1 more source

A Phase I, Randomized, Double‐Blind, Placebo‐Controlled, Single‐Dose and Multiple‐Rising‐Dose Study of the BTK Inhibitor TAK‐020 in Healthy Subjects

Clinical and Translational Science, 2021
Bruton’s tyrosine kinase (BTK) is a target for treatment of hematologic malignancies and autoimmune diseases. TAK‐020 is a highly selective covalent BTK inhibitor that inhibits both B cell receptor and fragment crystallizable receptor signaling.
Ehsanollah Esfandiari, Mary Chen, Glennda Smithson, Derek Blair, Helene Faessel, John Wagner, Lachy Mclean, Eric R. Fedyk   +7 more
doaj   +1 more source

A Novel Methodology for Developing Troubleshooting Chatbots Applied to ATM Technical Maintenance Support

Applied Sciences, 2023
The banking industry has been employing artificial intelligence (AI) technologies to enhance the quality of its services. More recently, AI algorithms, such as natural language understanding (NLU), have been integrated into chatbots to improve banking ...
Nádila Azevedo, Gustavo Aquino, Leonardo Nascimento, Leonardo Camelo, Thiago Figueira, Joel Oliveira, Ingrid Figueiredo, André Printes, Israel Torné, Carlos Figueiredo   +9 more
doaj   +1 more source

Pharmaceutical Cocrystal Development of TAK-020 with Enhanced Oral Absorption

Crystals, 2020
The objective of this study was to improve the solubility of poorly water-soluble drugs by pharmaceutical cocrystal engineering techniques and select the best pharmaceutical forms with high solubility and solubilized formulations for progress from the ...
Kouya Kimoto, Mitsuo Yamamoto, Masatoshi Karashima, Miyuki Hohokabe, Junpei Takeda, Katsuhiko Yamamoto, Yukihiro Ikeda   +6 more
doaj   +1 more source

A Comprehensive Framework for Industrial Sticker Information Recognition Using Advanced OCR and Object Detection Techniques

Applied Sciences, 2023
Recent advancements in Artificial Intelligence (AI), deep learning (DL), and computer vision have revolutionized various industrial processes through image classification and object detection.
Gabriella Monteiro, Leonardo Camelo, Gustavo Aquino, Rubens de A. Fernandes, Raimundo Gomes, André Printes, Israel Torné, Heitor Silva, Jozias Oliveira, Carlos Figueiredo   +9 more
doaj   +1 more source

Correction to: 10.1007/s40005-020-00480-1, 10.1007/s40005-020-00481-0, 10.1007/s40005-020-00482-z, and 10.1007/s40005-020-00484-x [PDF]

Journal of Pharmaceutical Investigation, 2020
The article Emerging nanoparticulate drug delivery systems of metformin, written by Yao Chen, Xinzhu Shan, Cong Luo and Zhonggui He, was originally published Online First without Open Access.
openaire   +1 more source

THE ROLE OF SCHOOL PRINCIPAL IN IMPROVING TEACHER'S PROFESSIONAL COMPETENCE IN THE ELEMENTARY SCHOOL

Jurnal PAJAR (Pendidikan dan Pengajaran), 2020
This research is motivated by the needs to increase teacher’s professional competence. This research was conducted at SDN 020 Serumpun Jaya. The subjects of this study were all teachers in SDN 020 Serumpun Jaya, totaling 9 teachers.
Raja Mista
doaj   +1 more source

Development of a Monitoring System against Illegal Deforestation in the Amazon Rainforest Using Artificial Intelligence Algorithms

Engineering Proceedings, 2023
The Amazon Rainforest represents one-third of the world’s tropical forest area. This makes it indispensable for maintaining global biodiversity. However, the increasing occurrences of wildfires and deforestation in the region are notorious. In this sense,
Thiago Almeida Teixeira, Neilson Luniere Vilaça, Andre Luiz Printes, Raimundo Claúdio Souza Gomes, Israel Gondres Torné, Thierry-Yves Alves Araújo, Arlley Gabriel Dias e Dias   +6 more
doaj   +1 more source