ApoJ regulates endothelial lipase activity and stability
Abstract Endothelial lipase (EL) is a key regulator of high‐density lipoprotein (HDL) metabolism. Many aspects of EL function remain incompletely understood due to challenges in purifying active EL. This study identifies apolipoprotein J (ApoJ) as a novel chaperone for EL, crucial for its solubility and activity.
Uriel L. Jean‐Baptiste +5 more
wiley +1 more source
Correction: Li et al. The Therapeutic Potential of Four Main Compounds of <i>Zanthoxylum nitidum</i> (Roxb.) DC: A Comprehensive Study on Biological Processes, Anti-Inflammatory Effects, and Myocardial Toxicity. <i>Pharmaceuticals</i> 2024, <i>17</i>, 524. [PDF]
Li X +11 more
europepmc +1 more source
ERRATUM: Impact of an educational intervention on postpartum depression for primary care nurses: a quasi-experimental study. [PDF]
europepmc +1 more source
Catatonia and elevated mortality: A population-wide cohort study with healthy, sibling, and schizophrenia spectrum controls. [PDF]
Hsu CW +7 more
europepmc +1 more source
Abstract While historically, the aim of propaganda was to convince the public of a certain agenda, many political commentators contend that modern forms of disinformation come with a different goal in mind: To confuse, rather than convince. It is believed that to secure this goal, informational spaces are diluted, rather than dominated, a strategy ...
Helen Fischer +5 more
wiley +1 more source
Unraveling the metabolic potential and roles of reductases in the omicsynin biosynthetic gene cluster. [PDF]
Li Y +8 more
europepmc +1 more source
We curate laccase‐substrate datasets and train five classifiers, from regularized logistic regression to tree‐based models and ChemBERTa, to predict whether a substrate will be oxidized. Feature importance and attention maps projected onto molecular substructures make the predictions interpretable and useful for pre‐screening before the bench ...
Yulia Kulagina +3 more
wiley +1 more source
ABSTRACT Background With population aging and extended healthy life expectancy, the management of acute cholecystitis (AC) in patients aged ≥ 85 years has evolved. However, the Tokyo Guidelines 2018 (TG18) for AC provide no specific risk assessment criteria for this population.
Yuta Kobayashi +9 more
wiley +1 more source
ABT-263, a BCL-2 inhibitor, selectively eliminates latently HIV-1-infected cells without viral reactivation. [PDF]
Kang JE +5 more
europepmc +1 more source

