Results 141 to 150 of about 41,517 (231)

ApoJ regulates endothelial lipase activity and stability

open access: yesProtein Science, Volume 35, Issue 4, April 2026.
Abstract Endothelial lipase (EL) is a key regulator of high‐density lipoprotein (HDL) metabolism. Many aspects of EL function remain incompletely understood due to challenges in purifying active EL. This study identifies apolipoprotein J (ApoJ) as a novel chaperone for EL, crucial for its solubility and activity.
Uriel L. Jean‐Baptiste   +5 more
wiley   +1 more source

Zone‐flooding, public confusion, and signal detection theory: A theoretical framework and registered report

open access: yesPolitical Psychology, Volume 47, Issue 2, April 2026.
Abstract While historically, the aim of propaganda was to convince the public of a certain agenda, many political commentators contend that modern forms of disinformation come with a different goal in mind: To confuse, rather than convince. It is believed that to secure this goal, informational spaces are diluted, rather than dominated, a strategy ...
Helen Fischer   +5 more
wiley   +1 more source

Unraveling the metabolic potential and roles of reductases in the omicsynin biosynthetic gene cluster. [PDF]

open access: yesNat Prod Bioprospect
Li Y   +8 more
europepmc   +1 more source

Machine Learning Prediction of Laccase‐Catalyzed Oxidation of Aromatic Compounds Using Curated Enzyme‐Specific Datasets

open access: yesJournal of Computational Chemistry, Volume 47, Issue 7, March 15, 2026.
We curate laccase‐substrate datasets and train five classifiers, from regularized logistic regression to tree‐based models and ChemBERTa, to predict whether a substrate will be oxidized. Feature importance and attention maps projected onto molecular substructures make the predictions interpretable and useful for pre‐screening before the bench ...
Yulia Kulagina   +3 more
wiley   +1 more source

Validation of the Safe Application of Tokyo Guideline 2018 (TG18) Severity Grading and Treatment Algorithm in Super‐Elderly Patients Aged 85 and Over With Acute Cholecystitis: A Study in the Japanese Tertiary Care Hospital

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 2, Page 570-577, March 2026.
ABSTRACT Background With population aging and extended healthy life expectancy, the management of acute cholecystitis (AC) in patients aged ≥ 85 years has evolved. However, the Tokyo Guidelines 2018 (TG18) for AC provide no specific risk assessment criteria for this population.
Yuta Kobayashi   +9 more
wiley   +1 more source

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