Results 21 to 30 of about 310,777 (333)

GX15–070 (Obatoclax), a Bcl-2 family proteins inhibitor engenders apoptosis and pro-survival autophagy and increases Chemosensitivity in neuroblastoma

BMC Cancer, 2019
Background Neuroblastoma (NB) is a frequent pediatric tumor associated with poor prognosis. The disregulation of Bcl-2, an anti-apoptotic protein, is crucial for the tumoral development and chemoresistance.
Sonia Cournoyer, Anissa Addioui, Assila Belounis, Mona Beaunoyer, Carine Nyalendo, Roxane Le Gall, Pierre Teira, Elie Haddad, Gilles Vassal, Hervé Sartelet   +9 more
doaj   +1 more source

Antimicrobial and Osteogenic Effects of Collagen Membrane Decorated with Chitosan–Nano-Hydroxyapatite

Biomolecules, 2023
Collagen membranes are routinely used in oral surgery for bone regeneration. Despite their numerous advantages, such as stimulating bone growth, bacterial contamination still remains one of the disadvantages of membrane use.
Milos Lazarevic, Sanja Petrovic, Tania Vanessa Pierfelice, Nenad Ignjatovic, Adriano Piattelli, Tamara Vlajic Tovilovic, Milena Radunovic   +6 more
doaj   +1 more source

A New ZZ Ceti White Dwarf Pulsator: G30-20 [PDF]

, 2002
We report the discovery of a new hydrogen atmosphere variable white dwarf (DAV; ZZ Ceti), G30-20, a high-amplitude, long-period pulsator. The Fourier transform of its light curve shows power around 1050-1125 s.
Bergeron, P., Kepler, S. O., Mukadam, Anjum S., Winget, D. E.   +3 more
core   +1 more source

Performance Analysis of Interval Type-2 Fuzzy $\overline{\mathbf{X}}$ and R Control Charts

Applied Sciences, 2023
Statistical process control (SPC) is one of the most powerful techniques for improving quality, as it is able to detect special causes of problems in processes, products and services with a remarkable degree of accuracy. Among SPC tools, X¯ and R control
Túlio S. Almeida, Amanda dos Santos Mendes, Paloma M. S. Rocha Rizol, Marcela A. G. Machado   +3 more
doaj   +1 more source

Antimetastatic Properties of Prodigiosin and the BH3-Mimetic Obatoclax (GX15-070) in Melanoma

Pharmaceutics, 2022
Metastasis is the primary cause of death in cancer patients. Many current chemotherapeutic agents only show cytotoxic, but not antimetastatic properties. This leads to a reduction in tumor size, but allows cancer cells to disseminate, which ultimately causes patient death. Therefore, novel anticancer compounds with both effects need to be developed. In
Margarita Espona-Fiedler, Pilar Manuel-Manresa, Cristina Benítez-García, Pere Fontova, Roberto Quesada, Vanessa Soto-Cerrato, Ricardo Pérez-Tomás   +6 more
openaire   +6 more sources

Intracranial Compliance Assessed by Intracranial Pressure Pulse Waveform

Brain Sciences, 2021
Background: Morphological alterations in intracranial pressure (ICP) pulse waveform (ICPW) secondary to intracranial hypertension (ICP >20 mmHg) and a reduction in intracranial compliance (ICC) are well known indicators of neurological severity.
Sérgio Brasil, Davi Jorge Fontoura Solla, Ricardo de Carvalho Nogueira, Manoel Jacobsen Teixeira, Luiz Marcelo Sá Malbouisson, Wellingson Silva Paiva   +5 more
doaj   +1 more source

Long‐term prognosis is associated with residual disease after neoadjuvant systemic therapy but not with initial nodal status

BJS (British Journal of Surgery), EarlyView., 2020
This long‐term follow‐up study determined survival rates in a Swedish national cohort of 417 patients with breast cancer who all had neoadjuvant systemic therapy (NAST). Sentinel lymph node biopsy (SLNB) was performed before NAST in clinically node‐negative and after NAST in clinically node‐positive patients.
L. Zetterlund, F. Celebioglu, T. Hatschek, J. Frisell, J. de Boniface   +4 more
wiley   +1 more source

Evaluation of the Microbial Profile on the Polydioxanone Membrane and the Collagen Membrane Exposed to Multi-Species Subgingival Biofilm: An In Vitro Study

Membranes, 2023
Dehiscence in surgeries involving membranes often leads to bacterial contamination, hindering the healing process. This study assessed bacterial colonization on various membrane materials.
Marcus Vinícius Cintra Moreira, Luciene C. Figueiredo, Marcelo Augusto Ruiz da Cunha Melo, Fabio Hideaki Uyeda, Lucas Daylor Aguiar da Silva, Tatiane Tiemi Macedo, Roberto Sacco, Carlos Fernando Mourão, Jamil A. Shibli, Bruno Bueno-Silva   +9 more
doaj   +1 more source

Clean Cut (adaptive, multimodal surgical infection prevention programme) for low‐resource settings: a prospective quality improvement study

BJS (British Journal of Surgery), EarlyView., 2020
Clean Cut is a multimodal, adaptive, checklist‐based infection prevention programme designed to improve compliance with six critical perioperative infection prevention practices. After introducing the programme at five hospitals in Ethiopia, compliance with critical infection prevention standards significantly improved and the relative risk of ...
J. A. Forrester, N. Starr, T. Negussie, D. Schaps, M. Adem, S. Alemu, D. Amenu, N. Gebeyehu, T. Habteyohannes, F. Jiru, A. Tesfaye, E. Wayessa, R. Chen, A. Trickey, S. Bitew, A. Bekele, T. G. Weiser   +16 more
wiley   +1 more source

ESLO - Omelette bande 070

, 2011
Extrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960. Le sous-corpus "omelette" représente les 96 réponses à la question sur la recette de l'omelette posée au cours des entretiens en face-à-face.
Blanc, Michel, Biggs, Patricia, Ross, John, Kay, Jack, Dalwood, Mary, Centre Orléanais de Recherche en Anthropologie et Linguistique   +5 more
openaire   +2 more sources