Results 131 to 140 of about 84,221 (197)

Antimicrobial Activities of some 4H-1,2,4-triazoles

, 2019
A series of 3,5-dialkyl-4-ethoxycarbonylamino-4H-1,2,4-triazoles and 3,5-dialkyl-4-tert-butoxycarbonylamino-4H-1,2,4-triazoles were tested for their in vitro antibacterial and antifungal activities in solid agar cultures against eight microorganisms. In tests, some of the compounds were shown to be very potent in vitro antifungal activity against the ...
Ucar F., Ikizler A.A., Demirbas N.D., Yasa I., Demirbas A., Genzer T.   +5 more
openaire   +3 more sources

Scientific support for preparing an EU position in the 56th Session of the Codex Committee on Pesticide Residues (CCPR)

EFSA Journal, Volume 23, Issue 10, October 2025.
Abstract The European Commission asked EFSA to provide support in the framework of Article 43 of Regulation (EC) No 396/2005 for the preparation of the EU position for 56th Session of the Codex Committee on Pesticide Residues (CCPR). In the current report, EFSA provided comments and recommendations on the Codex maximum residue limit (CXL) proposals ...
EFSA (European Food Safety Authority)
wiley   +1 more source

Mechanism of action of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent.

Proceedings of the National Academy of Sciences of the United States of America, 1973
D. Streeter, J. T. Witkowski, G. Khare, R. Sidwell, R. J. Bauer, R. K. Robins, L. Simon   +6 more
semanticscholar   +1 more source

Nitrogen-rich salts based on the combination of 1,2,4-triazole and 1,2,3-triazole rings: a facile strategy for fine tuning energetic properties

, 2018
Zhen Xu, G. Cheng, Shun-guan Zhu, Qiu-han Lin, Hongwei Yang   +4 more
semanticscholar   +1 more source

1,2,4‐Triazole‐3‐thione Compounds as Inhibitors of Dizinc Metallo‐β‐lactamases

ChemMedChem, 2017
Laurent Sevaille, Laurent Gavara, C. Bebrone, F. De Luca, L. Nauton, M. Achard, P. Mercuri, Silvia Tanfoni, Luisa Borgianni, C. Guyon, Pauline Lonjon, G. Turan-Zitouni, Julia Dzieciolowski, K. Becker, L. Bénard, C. Condon, L. Maillard, Jean Martinez, J. Frère, O. Dideberg, M. Galleni, J. Docquier, Jean‐François Hernandez   +22 more
semanticscholar   +1 more source

Electrochemical synthesis of 1,2,4-triazole-fused heterocycles

, 2018
Zenghui Ye, Mingruo Ding, Yanqi Wu, Yong Li, Wen-Jun Hua, Fengzhi Zhang   +5 more
semanticscholar   +1 more source

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Strategies for synthesis of 1,2,4-triazole-containing scaffolds using 3-amino-1,2,4-triazole

Molecular Diversity, 2021
1,2,4-Triazole-containing scaffolds are unique heterocyclic compounds present in an array of pharmaceuticals and biologically important compounds used in the drug-discovery studies against cancer cells, microbes, and various types of disease in the human body.
Shima Nasri, M. Bayat, Khudaidad Kochia
semanticscholar   +3 more sources

1,5-Diaryl-1,2,4-triazole Ureas as New SLC-0111 Analogues Endowed with Dual Carbonic Anhydrase and VEGFR-2 Inhibitory Activities.

Journal of Medicinal Chemistry, 2023
Presently, dual targeting by a single small molecule stands out as an effective cancer-fighting weapon. Carbonic anhydrase (CA) and vascular-endothelial growth factor (VEGF) are hypoxia-activatable genes that are implicated in tumorigenesis and ...
Ahmed E Elsawi, Mostafa M. Elbadawi, A. Nocentini, Hadia Almahli, Simone Giovannuzzi, M. Shaldam, Rofaida Salem, Tamer M. Ibrahim, H. Abdel‐Aziz, C. Supuran, Wagdy M. Eldehna   +10 more
semanticscholar   +1 more source

The antibacterial activity of 1,2,3-triazole- and 1,2,4-triazole-containing hybrids against Staphylococcus aureus: An updated review (2020-present).

Current Topics in Medicinal Chemistry, 2021
Staphylococcus aureus (S. aureus), a prominent, highly contagious nosocomial and community-acquired bacterial pathogen, can cause a broad spectrum of diseases. Antibiotic-resistant S. aureus strains, which pose potential causes of morbidity and mortality,
Jie Li, Junwei Zhang
semanticscholar   +1 more source

Synthetic and Medicinal Perspective of 1,2,4‐Triazole as Anticancer Agents

Chemistry and Biodiversity, 2022
Cancer is still one of the leading causes of death worldwide. Many researchers are working to design and develop heterocyclic‐based drugs with the potential to treat cancer at various stages. There is always an unmet need to discover new anticancer drugs
B. Rathod, K. Kumar
semanticscholar   +1 more source