Results 111 to 120 of about 18,261 (204)

Structure-Guided Optimization and Biological Validation of 1,3,4-Thiadiazole-Based SIRT2 Inhibitors Reinforcing Channel Entrance Interactions. [PDF]

Drug Dev Res
Aksel AB, Ozgencil F, Bakar-Ates F, Gunindi HB, Massarotti A, Ozkan E, Kaya SG, Gozelle M, Ozkan Y, Eren G.   +9 more
europepmc   +1 more source

Design synthesis and evaluation of a novel 1,3,4-thiadiazole derivative as a potent anticancer and antibacterial agent supported by electronic property analysis and simulation studies. [PDF]

Sci Rep
Alawam AS, Rajesh R, Verma AK, Dadhich A, Choudri V, Rudayni HA, Alamri MA, Bohra MK.   +7 more
europepmc   +1 more source

Structural design and cytotoxic profiling of a novel 1,3,4-thiadiazole derivative targeting MCF-7 and HCT-116 cell lines: synthesis, cytotoxicity, and <i>in silico</i> study. [PDF]

RSC Adv
Sayed M, Mohammed E, Aboubaker DH, El-Rashedy AA, Hassanien R, Tolba MS, Ahmed M.   +6 more
europepmc   +1 more source

Exploring Novel Nitrofuryl-1,3,4-Thiadiazole-Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity. [PDF]

Arch Pharm (Weinheim)
Mousavi A, Slapničková M, Norouzbahari M, D'Alessandro S, Foroumadi P, Peytam F, Perego F, Doleželová E, Emamgholipour Z, Tehrani MB, Sadat-Ebrahimi SE, Hosseinzadeh E, Ahadi EM, Firoozpour L, Bijanzadeh H, Basilico N, Zíková A, Foroumadi A.   +17 more
europepmc   +1 more source

Corrosion inhibition of ductile iron in hydrochloric acid using 5-amino-1,3,4-thiadiazole-2-thiol: electrochemical and computational studies. [PDF]

Sci Rep
Helmy M, El-Zomrawy AA, Mogoda AS, Nasser A, Mahmoud M, Mohamed TA.   +5 more
europepmc   +1 more source

Thiazolyl-Methylthio-1,3,4-Thiadiazole Hybrids as Halicin Analogues with Antimicrobial and Antibiofilm Activities: Chemical Development, Biological Assessment, and 2D-QSAR Study. [PDF]

Antibiotics (Basel)
Ungureanu D, Marc G, Duma MN, Vodnar DC, Martău GA, Vlase L, Pîrnău A, Tiperciuc B, Moldovan C, Ionuț I, Stana A, Oniga I, Oniga O.   +12 more
europepmc   +1 more source

Synthesis, characterization, molecular docking and in vitro anti-arthritic activity of some novel spiro [1,3,4] thiadiazole derivatives based on thioxoacetamides. [PDF]

BMC Chem
El-Saghier AM, Abdul-Baset A, El-Hady OM, Abdou A, Hamed AM, Kadry AM.   +5 more
europepmc   +1 more source

Synthesis, Structure, and Magnetic and Biological Properties of Copper(II) Complexes with 1,3,4-Thiadiazole Derivatives. [PDF]

Int J Mol Sci, 2023
Lavrenova LG, Sukhikh TS, Glinskaya LA, Trubina SV, Zvereva VV, Lavrov AN, Klyushova LS, Artem'ev AV.   +7 more
europepmc   +1 more source

An Imidazo[2,1-b][1,3,4]thiadiazole Derivative Inhibits the Virulence Factor α-Hemolysin by Blocking the Pullout of Its Stem Domain. [PDF]

ChemMedChem
Korotkov VS, Lukat P, Di Lucrezia R, Shekhar A, Degenhart C, Diestel R, Bilitewski U, Dinkel K, Blankenfeldt W, Brönstrup M.   +9 more
europepmc   +1 more source

Synthesis, biological and molecular modelling for 1,3,4-thiadiazole sulfonyl thioureas: bacterial and fungal activity. [PDF]

RSC Med Chem, 2023
Dinh Thanh N, Ngoc Toan V, Thi Kim Giang N, Thi Kim Van H, Son Hai D, Minh Tri N, Ngoc Toan D.   +6 more
europepmc   +1 more source