Results 11 to 20 of about 5,199 (169)

Polysaccharide utilization loci and nutritional specialization in a dominant group of butyrate-producing human colonic Firmicutes [PDF]

, 2015
Acknowledgements The Rowett Institute of Nutrition and Health (University of Aberdeen) receives financial support from the Scottish Government Rural and Environmental Sciences and Analytical Services (RESAS).
Bernalier-Donadille, Annick, Browne, Hilary P., Duncan, Sylvia H., Flint, Harry J., Harris, Hugh M. B., Lawley, Trevor D., Martin, Jennifer C., O'Toole, Paul W., Scott, Karen P., Sheridan, Paul O.   +9 more
core   +3 more sources

Assembly of α-Glucan by GlgE and GlgB in Mycobacteria and Streptomycetes [PDF]

, 2016
Actinomycetes, such as mycobacteria and streptomycetes, synthesize α-glucan with α-1,4 linkages and α-1,6 branching to help evade immune responses and to store carbon.
Abdul M. Rashid, Bailey J. M., Cywes C., Farzana Miah, Guzman L. M., Hendrik Koliwer-Brandl, J. Elaine Barclay, Karl Syson, Karol P. Nartowski, Kieser T., Kim C. Findlay, McCleary B. V., Misaki A., Preiss J., Rainer Kalscheuer, Sibyl F. D. Batey, Stephen Bornemann, Summer R., Yaroslav Z. Khimyak   +18 more
core   +2 more sources

ApuA, a multifunctional x-glucan-degrading enzyme of Streptococcus suis, mediates adhesion to porcine epithelium and mucus [PDF]

, 2010
We have identified apuA in Streptococcus suis, which encodes a bifunctional amylopullulanase with conserved -amylase and pullulanase substrate-binding domains and catalytic motifs.
Ferrando, M.L., Fuentes, S., Greeff, A., de, Smith, H.E., Wells, J.   +4 more
core   +2 more sources

Abundant copathologies of polyglucosan bodies, frontotemporal lobar degeneration with TDP‐43 inclusions and ageing‐related tau astrogliopathy in a family with a GBE1 mutation

Neuropathology and Applied Neurobiology, 2022
Adult polyglucosan body disease (APBD) is a progressive neurogenetic disorder caused by 1,4‐alpha‐glucan branching enzyme 1 (GBE1) mutation with an accumulation of polyglucosan bodies (PBs) in the central and peripheral nervous systems as a pathological ...
Maiko T Uemura, Eunran Suh, J. Robinson, K. Brunden, M. Grossman, D. Irwin, V. Lee, J. Trojanowski, Eddie B. Lee, V. V. Van Deerlin   +9 more
semanticscholar   +1 more source

Functional and structural characterization of plastidic starch phosphorylase during barley endosperm development [PDF]

, 2017
The production of starch is essential for human nutrition and represents a major metabolic flux in the biosphere. The biosynthesis of starch in storage organs like barley endosperm operates via two main pathways using different substrates: starch ...
Cuesta-Seijo, Jose A., Hägglund, Per, Krucewicz, Katarzyna, Meier, Sebastian, Palcic, Monica M., Ruzanski, Christian, Svensson, Birte   +6 more
core   +2 more sources

Plant cell walls: impact on nutrient bioaccessibility and digestibility [PDF]

, 2020
Cell walls are important structural components of plants, affecting both the bioaccessibility and subsequent digestibility of the nutrients that plant-based foods contain.
Edwards, Cathrina H., Grundy, Myriam M.-L., Holland, Claire, Ryden, Peter   +3 more
core   +3 more sources

Actinomyces spp. gene expression in root caries lesions [PDF]

, 2016
Background: studies of the distribution of Actinomyces spp. on carious and non-carious root surfaces have not been able to confirm the association of these bacteria with root caries, although they were extensively implicated as a prime suspect in root ...
Damé-Teixeira, N, Devine, DA, Do, T, Maltz, M, Parolo, CCF, Tugnait, A   +5 more
core   +2 more sources

Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET

Nature Communications, 2019
Iron Regulatory Protein 1 (IRP1) is a bifunctional cytosolic iron sensor. When iron levels are normal, IRP1 harbours an iron-sulphur cluster (holo-IRP1), an enzyme with aconitase activity.
Nhan Huynh, Q. Ou, Pendleton J M Cox, R. Lill, K. King-Jones   +4 more
semanticscholar   +1 more source

Whole-exome sequencing in 16,511 individuals reveals a role of the HTRA1 protease and its substrate EGFL8 in brain white matter hyperintensities

medRxiv, 2021
White matter hyperintensities (WMH) are among the most common radiological abnormalities in the ageing population and an established risk factor for stroke and dementia. While common variant association studies have revealed multiple genetic loci with an
R. Malik, Nathalie Beaufort, S. Frerich, B. Gesierich, Marios K. Georgakis, Kristiina Rannikmäe, Amy Ferguson, C. Haffner, M. Traylor, M. Ehrmann, C. Sudlow, M. Dichgans   +11 more
semanticscholar   +1 more source

Synthesis of α-glucan in mycobacteria involves a hetero-octameric complex of trehalose synthase TreS and Maltokinase Pep2 [PDF]

, 2013
Recent evidence established that the cell envelope of Mycobacterium tuberculosis, the bacillus causing tuberculosis (TB), is coated by an α-glucan-containing capsule that has been implicated in persistence in a mouse infection model.
Alderwick, Luke J., Besra, Gurdyal S., Fütterer, Klaus, Hyde, Eva I., Kermani, Ali, Roy, Rana, Scott, David J., Usha, Veeraraghavan   +7 more
core   +2 more sources