Results 161 to 170 of about 1,529,781 (393)

THE IMPACT OF RESEARCH LED AGRICULTURAL PRODUCTIVITY GROWTH ON POVERTY REDUCTION IN AFRICA, ASIA AND LATIN AMERICA [PDF]

open access: yes
Twenty percent of the world population, or 1.2 billion live on less than $1 per day; 70% of these are rural and 90% in Asia and Sub-Saharan Africa. Research led technological change in agriculture generates sufficient productivity growth to give high ...
Lin, Lin   +2 more
core   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Rural Poverty in China: Problem and Policy [PDF]

open access: yes
This paper describes the economic conditions of rural China regarding poverty. By dividing the problem of rural poverty into three components it explains why rural poverty is China’s No.
Gregory C. Chow
core  

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Aid, the incentive regime, and poverty reduction [PDF]

open access: yes
Spurring growth in the developing world is one stated objective of foreign aid. Another, more commonly cited, objective is reducing poverty. Generally poverty reduction and growth go hand in hand, but could aid mitigate poverty without measurably ...
Burnside, Craig, Dollar, David
core  

Local Source Tsunami Inundation Modelling for Poverty Bay, Gisborne [PDF]

open access: yes, 2008
After the Boxing Day 2004 Sumatran Tsunami, a review of tsunami hazard and risk for New Zealand identified Gisborne as the urban area with the greatest risk.
Henderson, David Ronald
core   +1 more source

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