Results 121 to 130 of about 17,541,326 (249)

UK Medical Cannabis Registry: A Clinical Outcomes Analysis for Autism Spectrum Disorder. [PDF]

Neuropsychopharmacol Rep
Aggarwal A, Erridge S, Varadpande M, Clarke E, McLachlan K, Coomber R, Asghar M, Bhoskar U, Crews M, De Angelis A, Imran M, Kamal F, Korb L, Mwimba G, Sachdeva-Mohan S, Shaya G, Rucker JJ, Sodergren MH.   +17 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Cryogen-Aided Chromatographic Purification of Millimole Quantities of Methane for Spectroscopic Clumped Isotope Analysis. [PDF]

Rapid Commun Mass Spectrom
Kueter N, Meissner JGC, Zhang N, Msonnereau L, Emmenegger L, Mohn J, Bernasconi SM.   +6 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Cultural Adaptation and Measurement Properties of the Iranian Version of the Families' Importance in Nursing Care-Nurses Attitudes Questionnaire Based on COSMIN Checklist: A Methodological Study. [PDF]

Int J Methods Psychiatr Res
Dahouri A, Hosseinzadeh M, Sahebihagh MH, Meinag FM.   +3 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

柱塞泵液缸自增强工艺研究

Shiyou jixie, 2014
, 1, 〓
doaj  

The Kia Tīmata Pai Randomized Controlled Trial: ENRICH Early Childhood Teacher Training Improves Toddlers' Oral Language and Self-Regulation. [PDF]

Dev Sci
Reese E, Bakir-Demir T, Moses LJ, Marshall S, Schaughency E, Salmon K, Taumoepeau M, McLauchlan J, Edgeler C, Guiney H, Kokaua J, Jose PE, Clifford A, Maruariki N, Dorana Y, Zhang Y, Mollan S, McNaughton S.   +17 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Developing a Set of Core Patient-Reported Outcomes for Kidney Replacement Therapy: A Modified Delphi Study. [PDF]

J Ren Care
Nikolovski J, Smyth B, Muthuramalingam S, McDonald S, Roydhouse J, Aiyegbusi OL, Rutherford C, Luchterhand A, Cardelli P, Morton RL, ANZDATA PROMs Delphi Group.   +10 more
europepmc   +1 more source