Results 101 to 110 of about 17,541,326 (249)
Shiyou jixie, 2014 水下采油树油管悬挂器是水下生产系统的关键设备，其密封性能关系到深水石油开发的成败。介绍了国外ABB Vetco Gray公司、Cameron公司、DrilQuip公司和FMC公司的水下油管悬挂器密封技术，阐述了密封作用的原理，并对国外公司不同类型密封圈的性能进行了对比。同时分析了水下油管悬挂器密封的关键技术，总结了高温、高压、强腐蚀环境下油管悬挂器密封的发展趋势，最后指出金属与非金属组合的密封形式是当前水下油管悬挂器密封设计的主流，PTFE和PEEK等密封材料的发展将大大增强悬挂器的密封性能 ...
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Shiyou jixie, 2014 套铣存在施工持续时间长、卡钻风险高、受井况及落鱼材质影响制约施工效率等缺点。为此，针对渤海油田井况，通过数学建模和室内试验模拟井下套铣作业，对套铣管柱进行力学、水力学和材料学分析计算，得到了适合井眼直径、轨迹及落鱼材质的套铣工具尺寸、钻具组合的选择方法,以及影响套铣时效的钻压、转速和排量等重要参数的优化计算方法。采用该方法对套铣技术进行优化，优化后的套铣现场应用结果表明，在防砂井和注水井大修施工时，采用分段套铣解卡技术成功率很高，而且对于出砂、结垢和落物等造成的卡钻适用性较强 ...
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Shiyou jixie, 2014 对P110与TP140 2种不同的套管材料与超级13Cr油管材料的磨损性能进行了试验研究。通过对失质量、摩擦因数和往复磨损效率的对比研究，揭示了超级13Cr油管材料与不同套管材料的磨损特性。试验结果表明，TP140钢由于硬度比P110钢高，所以在单位时间内对超级13Cr钢造成的磨损更为严重。在恒定介质中，2对摩擦副的摩擦因数随着接触力和摩擦频率的改变变化不大。分析磨损表面形貌，结果表明超级13Cr油管材料表面磨损形貌为片状剥落和犁沟共存。
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doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Analysis of Bond Strength of Bioceramic Sealer Following Irrigation with Chlorhexidine. [PDF]
Iran Endod JCosta LG +5 more
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Short communication: performance of beef cows fed Kernza intermediate wheatgrass straw mixed with alfalfa haylage. [PDF]
Transl Anim SciPizarro DM +3 more
europepmc +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source