Results 51 to 60 of about 26,640,317 (249)
Zhongshan Daxue xuebao. Yixue kexue ban, 1994 介绍ＡＢＡ－１００型自动生化分析仪测定血中果糖胺的方法，对能引起果糖胺值波动，且在各实验室使用不一致的某些反应条件（如温度、比色时间、显色剂浓度、样品与试剂体积比等）进行了观察与分析。利用此法测定果糖胺，方法线性良好，批内与批间变异系数分别为１．３２％和２．４１％，回收率平均为９７％，优于手工测定，成人血清果糖胺的正常参考值（ｘ±ｓ）为２．２４±０．２６ｍｍｏｌ／Ｌ（１．７～２．８ｍｍｏｌ／Ｌ，ｎ＝１４４），与国外多数报道近似．
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Shiyou jixie, 2014 为配套海上采油平台而设计了2 250 kN海洋钻修机模块。2 250 kN海洋钻修机模块在设计上充分满足平台布局要求紧凑性和模块化的要求，采用联合驱动的传动系统设计也满足用户对钻机模块经济性的要求。井架结构设计打破常规，采用从基段两侧进钻杆的方案及自升式结构，可满足钻机在不同区位作业的便捷性要求。绞车采用交流变频联合驱动的传动形式，底座采用大模块化的结构形式，从而满足CEPI和CEPJ固定式采油平台钻机作业区域小和移动跨距大的需求。该钻机设计中采用的一些新方法可降低固定式平台钻修机模块的建造成本 ...
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Shiyou jixie, 2014 加大隔水管处理系统技术研究力度，快速实现该系统的国产化对推动我国海洋石油装备的全面发展意义深远。在介绍国内、外隔水管处理系统发展现状的基础上，对隔水管处理系统进行了技术分析，主要包括卧式隔水管处理系统和立式隔水管处理系统，并将两者进行了对比，其主要不同为存储方式对平台结构的影响、工作效率与安全性、隔水管移运吊机和存储指梁。我国要开发具有自主知识产权的隔水管处理系统，需攻克的关键技术有隔水管移运载荷分析、控制系统设计及系统安全性设计。建议我国从立式隔水管处理系统入手，研究试制其重要单元设备 ...
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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Shiyou jixie, 2014 针对现有的偏心分注工具不能满足薄互层油藏小卡距细分注水、原K344型偏心封隔配水器不适应大斜度注水井分注的问题，研制了P2Y341-115型细分层封隔配水器。该工具将1个压缩式封隔器与2台偏心配水器的功能集成一体，实现多个连续薄夹层注水井的分注，并大幅提高测试调配效率。现场应用7口井，封卡最薄油层4.4 m，最大井斜31.75°，均完成了分层验封、分层流量测试及水嘴投捞，平均配注符合率达到89.8%，平均使用寿命达到1 a以上。
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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Shiyou jixie, 2015 针对页岩气“井工厂”的高效开发模式及关键技术，在详细阐述国外“井工厂”钻机技术特点的基础上，介绍了国产钻机在涪陵页岩气示范基地的应用现状，分析了国产钻机在“井工厂”作业中的不足，梳理了国内钻机制造厂商对钻机全方位高效移运技术和钻机自动化升级改造技术的探索研发情况，提出了适合我国今后页岩气开发的“井工厂”钻机一体化解决方案，从而形成适合我国页岩气开发特色的“井工厂”钻机技术。最后指出了页岩气“井工厂”钻机的发展趋势和钻机自动化发展重点。
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
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