Results 91 to 100 of about 7,265,567 (217)

Health economic considerations for pharmacogenomic services in the United Kingdom: The Centre for Excellence in Regulatory Science and Innovation in Pharmacogenomics

British Journal of Clinical Pharmacology, EarlyView.
Dyfrig A. Hughes, Henry Fong, Grace Hampson, Catrin O. Plumpton, Chris Sampson   +4 more
wiley   +1 more source

The effects of royal jelly on human health: A narrative review of clinical studies

JSFA reports, EarlyView.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras, Andreas Thrasyvoulou, Evanthia Tsilimpokou   +2 more
wiley   +1 more source

Assessing the hidden risks of non‐thermal processing: Ultrasound‐induced toxicity of cashew apple juice in a zebrafish model

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Background High‐intensity ultrasound is widely advocated for the preservation of liquid foods; however, the potential formation or release of toxic compounds during processing remains under‐investigated. This study evaluated the toxicological profile of cashew apple juice processed by high‐intensity ultrasound (1250, 1875, and 2500 W;L⁻¹ ...
Thaiz Batista Azevedo Rangel Miguel, Sergimar Kennedy de Paiva Pinheiro, Jorge Henrique de Andrade Vieira, Fabiano André Narciso Fernandes, Sueli Rodrigues, Emilio de Castro Miguel   +5 more
wiley   +1 more source

A Phase 1 Study of Convection‐Enhanced Delivery of Intraputaminal AAV2‐GDNF in Advanced Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is a progressive neurodegenerative disorder. Neurotrophic therapeutic approaches have been limited in part by incomplete delivery to the putamen. We developed image‐guided convection‐enhanced delivery with real‐time monitoring to improve intraputaminal distribution of neurotrophic gene therapy. Objectives To
John D. Heiss, Debra J. Ehrlich, Codrin Lungu, Joseph Y. Choi, Gretchen Scott, Irene Dustin, Dima A. Hammoud, Peter Herscovitch, Russell R. Lonser, Kareem A. Zaghloul, Krystof Bankiewicz   +10 more
wiley   +1 more source

Exploring fatty acids from royal jelly as a source of histone deacetylase inhibitors: from the hive to applications in human well-being and health

Epigenetics
A differential diet with royal jelly (RJ) during early larval development in honeybees shapes the phenotype, which is probably mediated by epigenetic regulation of gene expression.
Fernanda Aparecida dos Santos France, Debora Kazumi Maeda, Ana Beatriz Rodrigues, Mai Ono, Franciele Lopes Nogueira Marchetti, Marcos Martins Marchetti, Allana Cristina Faustino Martins, Roberto da Silva Gomes, Cláudia Aparecida Rainho   +8 more
doaj   +1 more source

Increasing Obesity Severity Is Associated With Less Surgical Care in the United States

Obesity, EarlyView.
ABSTRACT Objective Approximately 41% of the US population has obesity, though the prevalence of the highest BMI populations (e.g., ≥ 60 kg/m2) is increasing most rapidly. Given the association between obesity and surgical disease burden, we hypothesized that higher BMI groups would account for a growing proportion of operative volume over time.
Michael Kachmar, Florina Corpodean, Hector J. Garcia Navas, Molly Perkins, Carlos Galvani, Michael W. Cook, Denise M. Danos, David A. Hughes, Philip R. Schauer, Vance L. Albaugh   +9 more
wiley   +1 more source

Loss of ATP synthase restores growth of Hda deficient cells. [PDF]

, 2017
A) The hda::cat mutation was introduced into wild-type,ΔatpA and ΔatpB cells under anaerobic conditions, restreaked on LB plates and incubated under aerobic and anaerobic conditions.
Christopher Campion (3700816), Godefroid Charbon (539647), Louise Bjørn (3700810), Luís Cláudio Nascimento da Silva (3740716), Siu Hung Joshua Chan (538114), Anders Løbner-Olesen (59353), Peter Ruhdal Jensen (168177), Allan Weimann (350362)   +7 more
core   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

Environmental Toxicology, EarlyView.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa, Analía Ale, Azael Francisco Silva Neto, Lorena De Mendonça Lucena, Marcelo Estrella Josende, Milena Ferreira de Lima, Rhayanny Kethylly Pereira Santos, Martín Federico Desimone, Priscila Gubert, José María Monserrat   +9 more
wiley   +1 more source

Interaction of the sliding clamp -subunit and Hda, a DnaA related protein [PDF]

, 2004
In Escherichia coli, interactions between the replication initiation protein DnaA, the subunit of DNA polymerase III (the sliding clamp protein), and Hda, the recently identified DnaA-related protein, are required to convert the active ATP-bound form of
Brian Dalrymple, Gene Wijffels, Mareike Kurz, Kritaya Kongsuwan   +3 more
core  

Audiological Characteristics in Vestibular Schwannoma Patients

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Vestibular schwannoma (VS) is a benign tumor that originates from the Schwann cells of the vestibular nerve sheath in the internal auditory canal. This retrospective study collected data from patients with VS who underwent surgical treatment to identify their demographic characteristics and audiometric features.
Shan Zeng, Yi‐Yun Lou, Hui‐Qian Yu, Wei‐Dong Zhao, Wen‐Yan Li   +4 more
wiley   +1 more source