Results 71 to 80 of about 7,265,567 (217)

Dynamic assembly of Hda and the sliding clamp in the regulation of replication licensing [PDF]

, 2019
Regulatory inactivation of DnaA (RIDA) is one of the major regulatory mechanisms of prokaryotic replication licensing. In RIDA, the Hda-sliding clamp complex loaded onto DNA directly interacts with adenosine triphosphate (ATP)-bound DnaA and stimulates ...
Sutton, M.D., Chodavarapu, S., Kaguni, J.M., Chung, S., Cho, Y., Jin, K.S., Kim, J.S., Nanfara, M.T., Babu, V.M.P., Ghazy, M.A.   +9 more
core   +1 more source

Ten-year radiographic and functional outcomes in rheumatoid arthritis patients in remission compared to patients in low disease activity

Arthritis Research & Therapy, 2023
Background To compare the 10-year structural and functional prognosis between patients in sustained remission versus patients in sustained low disease activity (LDA) in early rheumatoid arthritis (RA).
Adeline Ruyssen-Witrand, Gregory Guernec, Julia Dupont, Diane Lapuyade, Frédéric Lioté, Olivier Vittecoq, Yannick Degboé, Arnaud Constantin   +7 more
doaj   +1 more source

High Density Area (HDA) 10-Spawning Stock Biomass (SSB) time series (left) and associated cross correlation functions (right). [PDF]

, 2015
These show maximum cross correlation between HDA 10 and SSB at a lag h = -1 for Western Scotian Shelf (WSS) cod and Eastern Scotian Shelf (ESS) cod and h = -6 for American plaice (See Table 4 for the models used to create the time series residuals).
Jeffrey A. Hutchings (635211), Emilie Reuchlin-Hugenholtz (706374), Nancy L. Shackell (531235)   +2 more
core   +1 more source

Mutations in hda-4 restore kin-29 mutant sleep and foraging phenotypes. [PDF]

, 2020
(A) Time course of minutes of quiescence in 1-hr bins after UVC irradiation (1,500 J/m2) of single and double mutants between kin-29 and hda-4 compared with wild type. Data are represented as the mean ± SEM (n > 10 animals).
David M. Raizen (8742261), Alexander M. van der Linden (8742258), Lindsey E. Lopes (6034133), Jeremy J. Grubbs (8742255)   +3 more
core   +1 more source

Cost‐effectiveness of DPYD genotyping prior to fluoropyrimidine‐based treatment for colorectal cancer in Wales

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background Regulatory guidance in the United Kingdom advises DPYD genotyping prior to fluoropyrimidine‐based treatment. This economic evaluation estimated the costs and outcomes associated with DPYD screening prior to prescribing fluoropyrimidines for colorectal cancer in Wales and also considers additional variants to those included in ...
Catrin O. Plumpton, Sian M. Morgan, Richard A. Adams, Samantha Cox, Angharad A. Rudkin, Megan Fealey, Craig Barrington, Michelle D. Wood, Dyfrig A. Hughes   +8 more
wiley   +1 more source

Interaural attenuation for Sennheiser HDA 200 circumaural earphones. [PDF]

, 2010
Interaural attenuation (IA) was evaluated for pure tones (frequency range 125 to 16000 Hz) using Sennheiser HDA 200 circumaural earphones and Telephonics TDH-39P earphones in nine unilaterally deaf subjects.
Brännström, Jonas, Lantz, Johannes
core   +1 more source

Design of Experiments-Assisted Development of Clotrimazole-Loaded Ionic Polymeric Micelles Based on Hyaluronic Acid

Nanomaterials, 2020
Polymeric micelles based on amphiphilic polysaccharides have some advantages as a carrier of poorly soluble lipophilic drugs thanks to their characteristic "core–shell" structure.
Laura Catenacci, Giorgio Marrubini, Milena Sorrenti, Silvia Rossi, Giuseppina Sandri, Franca Ferrari, Valentina Fagnani, Caterina Valentino, Maria Cristina Bonferoni   +8 more
doaj   +1 more source

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Abstract Irinotecan, a topoisomerase I inhibitor, is available as both non‐pegylated and pegylated formulations. The non‐pegylated formulation is licensed for use in advanced colorectal cancer either in combination with other agents or as monotherapy.
Dharmisha Chauhan, Cinzia Dello Russo, Jack Thompson, Dyfrig A. Hughes, Katherine Payne, Maria Tsakiroglou, Paul Ross, Rena Chauhan, Simon Jenkinson, Jessica Keen, Sophie Harding, Eleanor Lau, Michael Braun, Roshan Agarwal, Richard Adams, Elisabeth Rolf, Farah Al‐Sheikhli, Sarah Mitchell, Ruth Hammond, Rosie Roberts, Lorna Cairns, Shirley Heggarty, Janet Graham, Justin Mencel, Munir Pirmohamed   +24 more
wiley   +1 more source

Efficient and Durable Sulfion Oxidation Coupled With Hydrogen Production via Cu@Cu2S Heterostructured Nanowires

Carbon Energy, EarlyView.
We present a facile and liquid‐phase approach to synthesize Cu@Cu2S core‐shell heterostructure nanowires derived from copper nanowires at room temperature for robust sulfide oxidation reaction (SOR)‐assisted H2 generation. The Cu@Cu2S core‐shell heterostructure nanowires exhibit superior SOR activity with an ultralow potential of 0.3 V (vs.
Hongling Zhang, Jiangna Guo, Mengqi Yang, Xingyu Li, Ruixue Weng, Guanyu Liu, Sen Luo, Xiaoyu Dong, Chaowei Ma, Xun Cui, Peng Xiao, Wenjing Yang, Yihuang Chen, Yunhuai Zhang, Ming Zhou   +14 more
wiley   +1 more source

Synthesis of cyclopentadienyl capped polyethylene and subsequent block copolymer formation via hetero diels-alder (HDA) chemistry [PDF]

, 2011
In the current contribution it is demonstrated - for the first time - that poly(ethylene) (M̄=1 400 as well as 2 800 g a · mol -1, PDI=1.2) can be readily equipped with highly reactive cyclopentadienyl (Cp) end groups.
Christophe Boisson, Christopher Barner-Kowollik, D'Agosto, F., Boisson, C., Espinosa, Edgar, Glassner, Mathias, Edgar Espinosa, Barner-Kowollik, C., Glassner, M., D'Agosto, Franck, Franck D'Agosto, Espinosa, E., Barner-Kowollik, Christopher, Mathias Glassner, Boisson, Christophe   +14 more
core   +1 more source